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  • Rostedt, Josefin
    Linköping University, Department of Social and Welfare Studies. Linköping University, Faculty of Educational Sciences.
    Förskollärare planerar barns möten med matematik: Ett reflektivt skoldidaktiskt perspektiv2019Licentiate thesis, monograph (Other academic)
    Abstract [en]

    Nyckelord: förskola, planering, didaktik, matematikundervisning  This Licentiate thesis focuses on planning in Swedish preschool. The aim is to describe and analyze pre-school teacher's authentic planning of children's meetings with mathematics. The theoretical framing of the study consists of the reflective school didactic theory emphasizing, regardless of school form, teachers' responsibility for teaching. With the reflective school didactic theory, the planning process is described as important for teaching. The planning process consists of three pedagogical activities: intention – action – reflection. This study focuses on the pedagogical work that takes place away from action, which makes intention and reflection to the central concept of the study.

    The empirical material of the study has been produced using participatory observation. Field work has been carried out in a preschool on part time for two semesters in the academic year 2012/13 in a regular and authentic planning conversation. The results show that the pre-school teachers do plan children's meetings with mathematics by taking their starting point in reflection on planned and documented pedagogical events. There is thus a link between intention and reflection. The result shows that the team has construct a planning model of their own. The planning is not based on explicit expressed goal formulations about what to learn. The reasoning of possible learning comes in as part of their conversations about activities. The result also shows that planning creates conditions for meetings with a multitude of mathematics. However, the results discussion shows that there is room to develop reasoning about the ways in which children can make transitions from everyday mathematical representations to more abstract. The result also shows that there is a need to develop a mathematics didactic language in preschool.

    Nyckelord: förskola, planering, didaktik, matematikundervisning  This Licentiate thesis focuses on planning in Swedish preschool. The aim is to describe and analyze pre-school teacher's authentic planning of children's meetings with mathematics. The theoretical framing of the study consists of the reflective school didactic theory emphasizing, regardless of school form, teachers' responsibility for teaching. With the reflective school didactic theory, the planning process is described as important for teaching. The planning process consists of three pedagogical activities: intention – action – reflection. This study focuses on the pedagogical work that takes place away from action, which makes intention and reflection to the central concept of the study.

    The empirical material of the study has been produced using participatory observation. Field work has been carried out in a preschool on part time for two semesters in the academic year 2012/13 in a regular and authentic planning conversation. The results show that the pre-school teachers do plan children's meetings with mathematics by taking their starting point in reflection on planned and documented pedagogical events. There is thus a link between intention and reflection. The result shows that the team has construct a planning model of their own. The planning is not based on explicit expressed goal formulations about what to learn. The reasoning of possible learning comes in as part of their conversations about activities. The result also shows that planning creates conditions for meetings with a multitude of mathematics. However, the results discussion shows that there is room to develop reasoning about the ways in which children can make transitions from everyday mathematical representations to more abstract. The result also shows that there is a need to develop a mathematics didactic language in preschool.

  • Public defence: 2019-09-06 09:00 Originalet, Qulturum, Jönköping
    Taxbro, Knut
    Linköping University, Department of Medical and Health Sciences, Division of Drug Research. Linköping University, Faculty of Medicine and Health Sciences.
    Vascular access in cancer patients – clinical implications2019Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Central venous catheters (CVC) are vital for patients receiving chemotherapy not compatible with peripheral infusion. Thousands of centrally and peripherally inserted central venous catheters are inserted into patients with cancer each year. All types of intravascular catheters are associated with complications. These complications may be divided into infectious, thrombotic, mechanical and occlusive events. All of these events have the potential to harm patients and cause additional expense for the health-care system. Furthermore, the above-mentioned complications are largely avoidable through proper patient selection, insertion technique, hygiene precautions and catheter maintenance.

    Catheter-related infections and deep venous thrombosis are the two most common and feared CVC related complications. Infection in a catheter can cause lifethreatening bacteraemia, and thrombosis can lead to pulmonary embolisation, post-thrombotic syndrome and stenosis of the vessel affected. Many studies describing methods to minimise infectious complications associated with central venous catheters have been carried out. These methods appear to have been implemented in most modern advanced healthcare facilities resulting in a continual decrease in catheter-related infections over the last two decades. New implantation techniques, fewer infections and better catheter materials are likely to have contributed to the reduction in the incidence of catheter-related deep venous thrombosis (CR-DVT). Peripherally inserted central venous catheters (PICC) and subcutaneously implanted vascular access ports (PORT) are two very commonly used catheter devices for delivery of chemotherapy. International guidelines are unclear as to which device to choose due to the paucity of controlled trials.

    The aim of this thesis was to study complications related to central venous access devices used over long periods of time, usually for the delivery of chemotherapy. Vascular access in cancer patients – clinical implications We prospectively studied PORT complications (Study 1) over a six-month follow- up period. In Study 2, we assessed the number of common CVC-related micro- organisms that are transferred across PORT membrane contaminated by a controlled suspension of micro-organisms when a non-coring access needle is inserted using two different techniques. In the largest randomised controlled trial published on this topic (Study 3), we compared PICC with PORT regarding CRDVT and other catheter-related complications. The economic implications of using PICC or PORT were assessed from health-care system´s perspective (Study 4), using data on adverse events and clinical factors (implantation, treatments and dwell-time) from Study 3.

    Chemotherapy against various forms of cancer is very common. Implantation of PORT is one of the ten most common surgical procedures in Sweden according to the Swedish Perioperative Register. Hence, the topic in this thesis may be clinically relevant to many patients and their health care providers.

    We found that the incidence of catheter-related blood stream infection was very low in the cohorts studied. In general, PICCs are associated with significantly more CR-DVTs and adverse events than PORTs. The cost to the health-care system when using PICC is higher than for PORT when complications are included. Given the choice, patients about to commence chemotherapy appear to prefer PORT to PICC. PORT implantation is more painful than PICC insertion, but PICC appears to influence activities of daily life more than PORT.

    List of papers
    1. A prospective observational study on 249 subcutaneous central vein access ports in a Swedish county hospital
    Open this publication in new window or tab >>A prospective observational study on 249 subcutaneous central vein access ports in a Swedish county hospital
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    2013 (English)In: Acta Oncologica, ISSN 0284-186X, E-ISSN 1651-226X, Vol. 52, no 5, p. 893-901Article in journal (Refereed) Published
    Abstract [en]

    Background. Reliable central vein access is a fundamental issue in modern advanced oncological care. The aim of this study was to determine the incidence of complications and patient perception regarding central vein access ports. Methods. We prospectively studied 249 single lumen access ports implanted between 1 July 2008 and 15 March 2010 in a mixed patient population at a 500-bed secondary level hospital in Sweden. We determined the number of catheter days, infection rate and mechanical complications, as well as patient satisfaction regarding the access port, over a six-month follow-up period. Results. Two hundred and forty-four different patients received 249 ports yielding a total of 37 763 catheter days. Ultrasound and fluoroscopic guidance was used in 98% of procedures. Vein access was obtained percutanously by an anaesthesiologist in all cases. There was no case of pneumo- or haemothorax. The incidence of catheter-related bloodstream infection, was 0.05/1000 catheter days and the incidence of pocket/tunnel infection was 0.39/1000 catheter days. Clinically apparent deep vein thrombosis occurred in four patients (1.6%). Patient satisfaction was overall high. Conclusion. These results confirm that our team-based approach with written easily accessible evidence-based guidelines and a structured education programme leads to a very low complication rate and a high degree of patient satisfaction.

    Place, publisher, year, edition, pages
    Informa Healthcare, 2013
    National Category
    Medical and Health Sciences
    Identifiers
    urn:nbn:se:liu:diva-93959 (URN)10.3109/0284186X.2013.770601 (DOI)000318655300003 ()
    Note

    Funding Agencies|Futurum - the Academy for Healthcare, Jonkoping County Council, Jonkoping, Sweden||

    Available from: 2013-06-13 Created: 2013-06-13 Last updated: 2019-07-23
    2. Clinical impact of peripherally inserted central catheters vs implanted port catheters in patients with cancer: an open-label, randomised, two-centre trial
    Open this publication in new window or tab >>Clinical impact of peripherally inserted central catheters vs implanted port catheters in patients with cancer: an open-label, randomised, two-centre trial
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    2019 (English)In: British Journal of Anaesthesia, ISSN 0007-0912, E-ISSN 1471-6771, Vol. 122, no 6, p. 734-741Article in journal (Refereed) Published
    Abstract [en]

    Background

    Centrally inserted totally implanted vascular access ports (PORTs) and peripherally inserted central catheters (PICCs) are widely used for the administration of chemotherapy. Our aim was to study the incidence of catheter-related deep venous thrombosis in patients with cancer receiving chemotherapy through either a PICC or a PORT.

    Methods

    Adults with non-haematological cancer (mainly breast and colorectal) from two Swedish oncology centres were included and followed for up to 1 yr. Patients were randomly assigned to receive a single-lumen PICC or PORT. The primary end point was the occurrence of a clinically significant catheter-related deep venous thrombosis, and the secondary end point was a composite of adverse events related to the catheter: insertion complication, thrombosis, occlusion, infection, and mechanical problems.

    Results

    The trial recruited 399 participants (PICC, n=201; PORT, n=198) between March 2013 and February 2017. The PICCs were associated with 16 (8%) deep venous thromboses compared with two (1%) in the PORT group (HR=10.2; 95% confidence interval, 2.3–44.6; P=0.002). The overall incidence of composite adverse events was higher for patients with a PICC compared with those with a PORT (HR=2.7; 95% confidence interval, 1.6–4.6; P<0.001).

    Conclusions

    PICCs are associated with higher risk for catheter-related deep venous thrombosis and other adverse events when compared with PORTs. This increased risk should be considered when choosing a vascular access device for chemotherapy, especially in patients with solid malignancy.

    Place, publisher, year, edition, pages
    Elsevier, 2019
    Keywords
    central venous catheter; central venous catheter thrombosis; peripherally inserted central catheter line insertion; vascular access devices
    National Category
    Surgery
    Identifiers
    urn:nbn:se:liu:diva-158319 (URN)10.1016/j.bja.2019.01.038 (DOI)000467806400034 ()31005243 (PubMedID)2-s2.0-85064326103 (Scopus ID)
    Note

    Funding Agencies|Futurum (Academy for Healthcare, Jonkoping County Council, Sweden) [767451]; FORSS (Research Council in South East Sweden) [295881]

    Available from: 2019-07-02 Created: 2019-07-02 Last updated: 2019-08-12Bibliographically approved
  • Public defence: 2019-09-02 13:00 Belladonnasalen, Linköping
    Bergkvist, Max
    Linköping University, Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics and Oncology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Hand and Plastic Surgery.
    Studies on Polarised Light Spectroscopy2019Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    This thesis project focuses on measurements of dermal microcirculation during vascular provocations with polarised light spectroscopy. This is done with a non-invasive method commercially available as Tissue viability imaging (TiVi) which measures concentration and oxygenation of red blood cells in the papillary dermis. Three studies were done with human subjects and one with an animal model, to validate and compare the TiVi technique with laser Doppler flowmetry, which is an established method of measuring dermal microcirculation.

    The TiVi consists of a digital camera with polarisation filters in front of the flash and lens, with software for analysis of the picture. When taking a picture with the TiVi, the polarised light that is reflected on the skin surface is absorbed by the second filter over the lens (which is perpendicular to the first filter) but a portion of light penetrates the surface of the skin and is scattered when it is reflected on tissue components. This makes the light depolarised, passes the second filter, and produces a picture for analysis. The red blood cell (RBC) has a distinct absorption pattern that differs between red and green colour compared to melanin and other components of tissue. This difference is used by the software that calculates differences in each picture element and produces a measure of output which is proportional to the concentration of red blood cells. The oxygenation of RBC can also be calculated, as there is a difference in absorption depending on oxygen state.

    The first paper takes up possible sources of error such as ambient light, and the angle and distance of the camera. The main experiment was to investigate how the local heating reaction is detected with TiVi compared to LDF.

    In the second paper arterial and venous stasis are examined in healthy subjects with TiVi.

    The Third paper is an animal study where skin flaps were raised on pigs, and the vascular pedicle is isolated to enable control of inflow and outflow of blood.The measurements were made during partial venous, total venous, and total arterial occlusion. The TiVi recorded changes in the concentration of RBC, oxygenation and heterogeneity and the results were compared with those of laser Doppler flowmetry.

    In the fourth paper oxygenation and deoxygenation of RBC: s was studied. Studies were made on the forearms of healthy subjects who were exposed to arterial and venous occlusion. Simultaneous measurements were made with TiVi and Enhanced perfusion and oxygen saturation or EPOS, which is a new device that combines laser Doppler flowmetry and diffuse reflectance spectroscopy in one probe.

    With TiVi, one can measure RBC concentration and oxygenation in the area of an entire picture or in one or multiple user defined regions of interest (ROI). Methods such as laser Doppler flowmetry makes single point measurements, which is a potential source of error both because of the heterogeneity of the microcirculation, and that the circulation be insufficient in the margins of the investigated area. TiVi has been able to measure venous stasis more accurately than laser Doppler flowmetry, and venous stasis is the more common reason for flaps to fail.

    The TiVi is an accurate way to measure the concentration of RBC and trends in oxygenation of the dermal microcirculation. It has interesting possible applications for microvascular and dermatological research, monitoring of flaps, and diagnosis of peripheral vascular disease. Future clinical studies are needed as well as development of the user interface.  

    List of papers
    1. Polarized Light Spectroscopy for Measurement of the Microvascular Response to Local Heating at Multiple Skin Sites
    Open this publication in new window or tab >>Polarized Light Spectroscopy for Measurement of the Microvascular Response to Local Heating at Multiple Skin Sites
    2012 (English)In: Microcirculation, ISSN 1073-9688, E-ISSN 1549-8719, Vol. 19, no 8, p. 705-713Article in journal (Refereed) Published
    Abstract [en]

    Objective: To evaluate whether TiVi, a technique based on polarized light, could measure the change in RBC concentration during local heating in healthy volunteers. Methods: Using a custom-made transparent heater, forearm skin was heated to 42 degrees C for 40 minutes while the change in RBC concentration was measured with TiVi. The perfusion response during local heating was measured at the same time with Laser Doppler flowmetry. Results: Mean RBC concentration increased (91 +/- 34 vs. 51 +/- 34 A.U. at baseline, p less than 0.001). The spatial heterogeneity of the RBC concentration in the measured skin areas was 26 +/- 6.4% at baseline, and 23 +/- 4.6% after 40 minutes of heating. The mean RBC concentrations in two skin sites were highly correlated (0.98 at baseline and 0.96 after 40 minutes of heating). The change in RBC concentration was less than the change in perfusion, measured with LDF. Unlike with LDF, a neurally mediated peak was not observed with TiVi in most of the test subjects. Conclusions: TiVi is a valuable technique for measuring the microvascular response to local heating in the skin, and offers a high reproducibility for simultaneous measurements at different skin sites, provided carefully controlled experiments are ensured.

    Place, publisher, year, edition, pages
    Informa Healthcare / John Wiley and Sons, 2012
    Keywords
    tissue viability imaging; polarization light spectroscopy; local heating; red blood cell concentration; reproducibility
    National Category
    Medical and Health Sciences
    Identifiers
    urn:nbn:se:liu:diva-87225 (URN)10.1111/j.1549-8719.2012.00203.x (DOI)000311373400004 ()
    Available from: 2013-01-14 Created: 2013-01-14 Last updated: 2019-07-23
    2. Assessment of microcirculation of the skin using Tissue Viability Imaging: A promising technique for detecting venous stasis in the skin
    Open this publication in new window or tab >>Assessment of microcirculation of the skin using Tissue Viability Imaging: A promising technique for detecting venous stasis in the skin
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    2015 (English)In: Microvascular Research, ISSN 0026-2862, E-ISSN 1095-9319, Vol. 101, p. 20-25Article in journal (Refereed) Published
    Abstract [en]

    Background: : Venous occlusion in the skin is difficult to detect by existing measurement techniques. Our aim was to find out whether Tissue Viability Imaging (TiVi) was better at detecting venous occlusion by comparing it with results of laser Doppler flowmetry (LDF) during graded arterial and venous stasis in human forearm skin. Methods: : Arterial and venous occlusions were simulated in 10 healthy volunteers by inflating a blood pressure cuff around the upper right arm. Changes in the concentration of red blood cells (RBC) were measured using TiVi, while skin perfusion and concentration of moving red blood cells (CMBC) were measured using static indices of LDF during exsanguination and subsequent arterial occlusion, postocclusive reactive hyperaemia, and graded increasing and decreasing venous stasis. Results: : During arterial occlusion there was a significant reduction in the mean concentration of RBC from baseline, as well as in perfusion and CMBC (p less than 0.008). Venous occlusion resulted in a significant 28% increase in the concentration of RBC (p = 0.002), but no significant change in perfusion (mean change -14%) while CMBC decreased significantly by 24% (p = 0.02). With stepwise increasing occlusion pressures there was a significant rise in the TiVi index and reduction in perfusion (p = 0.008), while the reverse was seen when venous flow was gradually restored. Conclusion: : The concentration of RBC measured with TiVi changes rapidly and consistently during both total and partial arterial and venous occlusions, while the changes in perfusion, measured by LDF, were less consistent This suggests that TiVi could be a more useful, non-invasive clinical monitoring tool for detecting venous stasis in the skin than LDF.

    Place, publisher, year, edition, pages
    Elsevier, 2015
    Keywords
    Tissue viability imaging; Laser Doppler flowmetry; Post-occusive hyperaemia; Venous occlusion; Arterial occlusion
    National Category
    Clinical Medicine
    Identifiers
    urn:nbn:se:liu:diva-121302 (URN)10.1016/j.mvr.2015.06.002 (DOI)000360028500004 ()26092681 (PubMedID)
    Note

    Funding Agencies|County Council of Ostergotland, Sweden [2014JZ0004]

    Available from: 2015-09-16 Created: 2015-09-14 Last updated: 2019-07-23Bibliographically approved
    3. Vascular Occlusion in a Porcine Flap Model: Effects on Blood Cell Concentration and Oxygenation.
    Open this publication in new window or tab >>Vascular Occlusion in a Porcine Flap Model: Effects on Blood Cell Concentration and Oxygenation.
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    2017 (English)In: Plastic and reconstructive surgery. Global open, ISSN 2169-7574, Vol. 5, no 11, article id e1531Article in journal (Refereed) Published
    Abstract [en]

    Background: Venous congestion in skin flaps is difficult to detect. This study evaluated the ability of tissue viability imaging (TiVi) to measure changes in the concentration of red blood cells (CRBC), oxygenation, and heterogeneity during vascular provocations in a porcine fasciocutaneous flap model.

    Methods: In 5 pigs, cranial gluteal artery perforator flaps were raised (8 flaps in 5 pigs). The arterial and venous blood flow was monitored with ultrasonic flow probes. CRBC, tissue oxygenation, and heterogeneity in the skin were monitored with TiVi during baseline, 50% and 100% venous occlusion, recovery, 100% arterial occlusion and final recovery, thereby simulating venous and arterial occlusion of a free fasciocutaneous flap. A laser Doppler probe was used as a reference for microvascular perfusion in the flap.

    Results: During partial and complete venous occlusion, increases in CRBC were seen in different regions of the flap. They were more pronounced in the distal part. During complete arterial occlusion, CRBC decreased in all but the most distal parts of the flap. There were also increases in tissue oxygenation and heterogeneity during venous occlusion.

    Conclusions: TiVi measures regional changes in CRBC in the skin of the flap during arterial and venous occlusion, as well as an increase in oxygenated hemoglobin during venous occlusion that may be the result of reduced metabolism and impaired delivery of oxygen to the tissue. TiVi may provide a promising method for measuring flap viability because it is hand-held, easy to-use, and provides spatial information on venous congestion.

    Place, publisher, year, edition, pages
    Wolters Kluwer, 2017
    National Category
    Radiology, Nuclear Medicine and Medical Imaging Surgery
    Identifiers
    urn:nbn:se:liu:diva-145391 (URN)10.1097/GOX.0000000000001531 (DOI)29263951 (PubMedID)2-s2.0-85038559789 (Scopus ID)
    Available from: 2018-02-27 Created: 2018-02-27 Last updated: 2019-07-23Bibliographically approved
  • Palonen, H.
    et al.
    Uppsala Univ, Sweden.
    Mukhamedov, B. O.
    Natl Univ Sci and Technol MISIS, Russia.
    Ponomareva, A. V.
    Natl Univ Sci and Technol MISIS, Russia.
    Palsson, G. K.
    Uppsala Univ, Sweden.
    Abrikosov, Igor
    Linköping University, Department of Physics, Chemistry and Biology, Theoretical Physics. Linköping University, Faculty of Science & Engineering.
    Hjorvarsson, B.
    Uppsala Univ, Sweden.
    The magnetization profile induced by the double magnetic proximity effect in an Fe/Fe0.30V0.70 superlattice2019In: Applied Physics Letters, ISSN 0003-6951, E-ISSN 1077-3118, Vol. 115, no 1, article id 012406Article in journal (Refereed)
    Abstract [en]

    The double magnetic proximity effect (MPE) in an Fe/Fe0.30V0.70 superlattice is studied by a direct measurement of the magnetization profile using polarized neutron reflectivity. The experimental magnetization profile is shown to qualitatively agree with a profile calculated using density functional theory. The profile is divided into a short range interfacial part and a long range tail. The interfacial part is explained by charge transfer and induced magnetization, while the tail is attributed to the inhomogeneous nature of the FeV alloy. The long range tail in the magnetization persists up to 170% above the intrinsic ordering temperature of the FeV alloy. The observed effects can be used to design systems with a direct exchange coupling between layers over long distances through a network of connected atoms. When combined with the recent advances in tuning and switching, the MPE with electric fields and currents, the results can be applied in spintronic devices. Published under license by AIP Publishing.

  • Koppel, Lina
    et al.
    Linköping University, Department of Management and Engineering, Economics. Linköping University, Faculty of Arts and Sciences. Linköping University, Department of Clinical and Experimental Medicine, Center for Social and Affective Neuroscience. Linköping University, Faculty of Medicine and Health Sciences.
    Andersson, David
    Linköping University, Department of Management and Engineering, Economics. Linköping University, Faculty of Arts and Sciences. Linköping University, Department of Clinical and Experimental Medicine, Center for Social and Affective Neuroscience. Linköping University, Faculty of Medicine and Health Sciences.
    Västfjäll, Daniel
    Linköping University, Department of Behavioural Sciences and Learning, Psychology. Linköping University, Faculty of Arts and Sciences. Linköping University, Department of Clinical and Experimental Medicine, Center for Social and Affective Neuroscience. Linköping University, Faculty of Medicine and Health Sciences. Decis Res, OR USA.
    Tinghög, Gustav
    Linköping University, Department of Management and Engineering, Economics. Linköping University, Faculty of Arts and Sciences. Linköping University, Department of Clinical and Experimental Medicine, Center for Social and Affective Neuroscience. Linköping University, Faculty of Medicine and Health Sciences.
    No Effect of Ego Depletion on Risk Taking2019In: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 9, article id 9724Article in journal (Refereed)
    Abstract [en]

    We investigated the effect of ego depletion on risk taking. Specifically, we conducted three studies (total n= 1,716) to test the prediction that ego depletion results in decisions that are more strongly in line with prospect theory, i.e., that ego depletion reduces risk taking for gains, increases risk taking for losses, and increases loss aversion. Ego depletion was induced using two of the most common manipulations from previous literature: the letter e task (Studies 1 and 3) and the Stroop task (Study 2). Risk taking was measured using a series of standard, incentivized economic decision-making tasks assessing risk preferences in the gain domain, risk preferences in the loss domain, and loss aversion. None of the studies revealed a significant effect of ego depletion on risk taking. Our findings cast further doubts about the ability of ego-depletion manipulations to affect actual behavior in experimental settings.

  • Aho, Anna Carin
    et al.
    Malmo Univ, Sweden.
    Hultsjö, Sally
    Linköping University, Department of Medical and Health Sciences, Division of Nursing Science. Linköping University, Faculty of Medicine and Health Sciences. Cty Hosp Ryhov, Sweden.
    Hjelm, Katarina
    Uppsala Univ, Sweden.
    Perceptions of the transition from receiving the diagnosis recessive limb-girdle muscular dystrophy to becoming in need of human support and using a wheelchair: an interview study2019In: Disability and Rehabilitation, ISSN 0963-8288, E-ISSN 1464-5165, Vol. 41, no 19, p. 2289-2298Article in journal (Refereed)
    Abstract [en]

    Purpose: To describe perceptions of the transition from receiving the diagnosis recessive limb-girdle muscular dystrophy to becoming in need of human support to manage daily life and using a wheelchair for ambulation, from the affected young adults and their parents perspectives. Method: A qualitative and descriptive study design was used. Semi-structured interviews were held with 14 young adults diagnosed with recessive limb-girdle muscular dystrophy and 19 parents. Phenomenography was used for data analysis. Results: The diagnosis was described as being a shock and difficult to comprehend but also as a relief and a tool for information. Beginning to use a wheelchair was perceived to be mentally difficult but it also provided freedom. New ways of living involved physical, emotional, practical, and social difficulties as well as experiences of learning to adapt to the disease. The transition was overshadowed by concern about disease progression and influenced by facilitating factors, which were young adult being seen as a person; supportive family and friends; mobilized internal resources; meaningful daily activities; adapted environment; and professional support. Conclusions: The different perceptions expressed in this study highlight the importance of identifying personal perceptions and needs in order to optimize support provided by healthcare professionals.

  • Hoppe, Jens
    et al.
    Royal Inst Technol, Sweden; Inst Hautes Etud Sci, France.
    Tkatjev, Vladimir
    Linköping University, Department of Mathematics, Mathematics and Applied Mathematics. Linköping University, Faculty of Science & Engineering.
    New construction techniques for minimal surfaces2019In: Complex Variables and Elliptic Equations, ISSN 1747-6933, E-ISSN 1747-6941, Vol. 64, no 9, p. 1546-1563Article in journal (Refereed)
    Abstract [en]

    It is pointed out that despite the nonlinearity of the underlying equations, there do exist rather general methods that allow to generate new minimal surfaces from known ones.