Open this publication in new window or tab >>Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Department of Clinical, Educational and Health Psychology, University College London, London, UK; Faculty of Psychology and Educational Sciences, University of Leuven, Leuven, Belgium.
Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Gordon F. Derner School of Psychology, Adelphi University, Garden City, NY, USA.
Department of Psychology, Chestnut Hill College, Philadelphia, PA, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Weill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medicine, New York, NY, USA.
School of Psychology and Clinical Language Science, University of Reading, Reading, UK.
Department of Psychological Science, University of Liverpool, Liverpool, UK; Department of Psychology, University of Bologna, Bologna, Italy.
Department of Psychology, Stockholm University, Stockholm, Sweden.
Linköping University, Department of Behavioural Sciences and Learning, Psychology. Linköping University, Faculty of Arts and Sciences. Linköping University, Department of Biomedical and Clinical Sciences. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Otorhinolaryngology. Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Anna Freud National Center for Children and Families, London, UK.
Center for Emotions & Health, Dalhousie University, Halifax, Nova Scotia, Canada.
Center for Emotions & Health, Dalhousie University, Halifax, Nova Scotia, Canada.
Department of Psychology, Faculty of Human Science, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
National Institute of Psychiatry, Mexico City, Mexico.
National Institute of Psychiatry, Mexico City, Mexico.
Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; Psychiatric Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy.
Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; Psychiatric Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy.
Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Department of Developmental Psychology, Behavioural Science Institute, Radboud University, Nijmegen, the Netherlands.
Department of Clinical Psychology, Behavioural Science Institute, Radboud University, Nijmegen, Netherlands; Depression Expertise Center, Pro Persona Mental Health Care, Nijmegen, the Netherlands.
Department of Clinical, Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Department of Clinical Psychology, Behavioural Science Institute, Radboud University, Nijmegen, Netherlands; Depression Expertise Center, Pro Persona Mental Health Care, Nijmegen, the Netherlands.
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2023 (English)In: Clinical Psychology Review, ISSN 0272-7358, E-ISSN 1873-7811, Vol. 101, article id 102269Article, review/survey (Refereed) Published
Abstract [en]
BACKGROUND: Short-term psychodynamic psychotherapy (STPP) is frequently used to treat depression, but it is unclear which patients might benefit specifically. Individual participant data (IPD) meta-analyses can provide more precise effect estimates than conventional meta-analyses and identify patient-level moderators. This IPD meta-analysis examined the efficacy and moderators of STPP for depression compared to control conditions.
METHODS: PubMed, PsycInfo, Embase, and Cochrane Library were searched September 1st, 2022, to identify randomized trials comparing STPP to control conditions for adults with depression. IPD were requested and analyzed using mixed-effects models.
RESULTS: IPD were obtained from 11 of the 13 (84.6%) studies identified (n = 771/837, 92.1%; mean age = 40.8, SD = 13.3; 79.3% female). STPP resulted in significantly lower depressive symptom levels than control conditions at post-treatment (d = -0.62, 95%CI [-0.76, -0.47], p < .001). At post-treatment, STPP was more efficacious for participants with longer rather than shorter current depressive episode durations.
CONCLUSIONS: These results support the evidence base of STPP for depression and indicate episode duration as an effect modifier. This moderator finding, however, is observational and requires prospective validation in future large-scale trials.
Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Depression, Efficacy, Individual participant data Meta-analysis, Moderators, Outcome, Short-term psychodynamic psychotherapy
National Category
Applied Psychology
Identifiers
urn:nbn:se:liu:diva-193638 (URN)10.1016/j.cpr.2023.102269 (DOI)000958413900001 ()36958077 (PubMedID)2-s2.0-85150446223 (Scopus ID)
Note
Funding: Fund for Psychoanalytic Research of the American Psycho-analytic Association; Netherlands Organization of Scientific Research (NWO) [016]
2023-05-102023-05-102023-09-15Bibliographically approved