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Savarese, G., Vasko, P., Jonsson, Å., Edner, M., Dahlström, U. & Lund, L. H. (2019). The Swedish Heart Failure Registry: a living, ongoing quality assurance and research in heart failure. Upsala Journal of Medical Sciences, 124(1), 65-69
Open this publication in new window or tab >>The Swedish Heart Failure Registry: a living, ongoing quality assurance and research in heart failure
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2019 (English)In: Upsala Journal of Medical Sciences, ISSN 0300-9734, E-ISSN 2000-1967, Vol. 124, no 1, p. 65-69Article, review/survey (Refereed) Published
Abstract [en]

Heart failure (HF) represents a global pandemic. Although in HF with reduced ejection fraction (HFrEF) randomized controlled trials have provided effective treatments, prognosis still remains poor, with signals of undertreatment. HF with mid-range EF (HFmrEF) has no evidence-based therapy, and its characterization is ongoing. Trials in HF with preserved EF (HFpEF) have failed to provide any effective treatment, but there are several concerns about their design. Thus, current challenges in the HF field are: 1) optimizing the use of existing treatments in HFrEF; 2) developing and proving efficacy of new treatments, and of new use of existing treatments in HFpEF and HFmrEF. Here we describe how registry-based research can improve knowledge addressing the unmet needs in HF, and in particular we focus on the contribution of the Swedish Heart Failure Registry to this field.

Place, publisher, year, edition, pages
Upsala Medical Society, 2019
Keywords
Heart failure; RiksSvikt; SwedeHF; registry
National Category
Cancer and Oncology
Identifiers
urn:nbn:se:liu:diva-156008 (URN)10.1080/03009734.2018.1490831 (DOI)30092697 (PubMedID)
Available from: 2019-04-01 Created: 2019-04-01 Last updated: 2019-04-01
Dahlström, U. (2018). Bröstsmärta. In: Ulf Dahlström, Stergios Kechagias, Leif Stenke (Ed.), Internmedicin: (pp. 97-100). Stockholm: Liber, Sidorna 97-100
Open this publication in new window or tab >>Bröstsmärta
2018 (English)In: Internmedicin / [ed] Ulf Dahlström, Stergios Kechagias, Leif Stenke, Stockholm: Liber, 2018, Vol. Sidorna 97-100, p. 97-100Chapter in book (Other academic)
Place, publisher, year, edition, pages
Stockholm: Liber, 2018
Keywords
Smärta, Bröst
National Category
Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-163167 (URN)9789147113262 (ISBN)
Available from: 2020-01-20 Created: 2020-01-20 Last updated: 2020-01-21Bibliographically approved
Dahlström, U. (2018). Chock (6ed.). In: Ulf Dahlström, Stergios Kechagias, Leif Stenke (Ed.), Internmedicin: (pp. 223-228). Stockholm: Liber, Sidorna 223-228
Open this publication in new window or tab >>Chock
2018 (Swedish)In: Internmedicin / [ed] Ulf Dahlström, Stergios Kechagias, Leif Stenke, Stockholm: Liber, 2018, 6, Vol. Sidorna 223-228, p. 223-228Chapter in book (Other academic)
Place, publisher, year, edition, pages
Stockholm: Liber, 2018 Edition: 6
Keywords
Chock
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:liu:diva-163174 (URN)9789147113262 (ISBN)
Available from: 2020-01-21 Created: 2020-01-21 Last updated: 2020-01-21Bibliographically approved
Dahlström, U. (2018). Dyspné (6ed.). In: Ulf Dahlström, Stergios Kechagias, Leif Stenke (Ed.), Internmedicin: (pp. 101-103). Stockholm: Liber, Sidorna 101-103
Open this publication in new window or tab >>Dyspné
2018 (Swedish)In: Internmedicin / [ed] Ulf Dahlström, Stergios Kechagias, Leif Stenke, Stockholm: Liber, 2018, 6, Vol. Sidorna 101-103, p. 101-103Chapter in book (Other academic)
Place, publisher, year, edition, pages
Stockholm: Liber, 2018 Edition: 6
Keywords
Andning
National Category
Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-163168 (URN)9789147113262 (ISBN)
Available from: 2020-01-20 Created: 2020-01-20 Last updated: 2020-01-21Bibliographically approved
Lund, L. H., Svennblad, B., Dahlström, U. & Ståhlberg, M. (2018). Effect of expanding evidence and evolving clinical guidelines on the prevalence of indication for cardiac resynchronization therapy in patients with heart failure. European Journal of Heart Failure, 20(4), 769-777
Open this publication in new window or tab >>Effect of expanding evidence and evolving clinical guidelines on the prevalence of indication for cardiac resynchronization therapy in patients with heart failure
2018 (English)In: European Journal of Heart Failure, ISSN 1388-9842, E-ISSN 1879-0844, Vol. 20, no 4, p. 769-777Article in journal (Refereed) Published
Abstract [en]

AIMS: To assess the prevalence of indication for cardiac resynchronization therapy (CRT) in patients with heart failure (HF) and reduced ejection fraction (EF) when recommendations from evolving European Society of Cardiology (ESC) guidelines are considered.

METHODS AND RESULTS: Unique patients (n=17 193) with EF ≤39% and key data available for evaluation of CRT indication from the Swedish HF Registry were included. Indication for CRT was defined as either CRT implanted or CRT device absent but fulfilling criteria for class I-IIa recommendations in ESC guidelines published between 2005/2007 and 2016. Prevalence was calculated as the ratio of patients with CRT indication to the study population. The prevalence of CRT indication increased from 24.5% when the 2005/2007 ESC guidelines were considered to a peak of 30.0% when the 2013 ESC guidelines were considered (P<0.001, 22.4% relative increase). Compared to the 2013 ESC guidelines, the prevalence declined significantly when the 2016 ESC guidelines were used as determinant for CRT indication (26.8%, 10.7% relative reduction, P<0.001). Actual CRT utilization was 6.8%.

CONCLUSION: Among patients with HF and reduced EF, the prevalence of CRT indication increased significantly comparing recommendations from ESC guidelines published between 2005/2007 and 2013, but then declined when the 2016 ESC guidelines were considered. The 2005-2013 increase may reflect the expansion of documented CRT efficacy to New York Heart Association class II, whereas the subsequent drop likely results from the more stringent criteria for QRS duration in the 2016 ESC guidelines. Actual CRT utilization is lower than indicated, regardless of which guidelines are considered.

Place, publisher, year, edition, pages
John Wiley & Sons, 2018
Keywords
Cardiac resynchronization therapy, Guidelines, Heart failure, Implementation, QRS width
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:liu:diva-144356 (URN)10.1002/ejhf.929 (DOI)000430105300024 ()28949083 (PubMedID)
Available from: 2018-01-16 Created: 2018-01-16 Last updated: 2018-07-23Bibliographically approved
Dahlström, U. (2018). Hjärt- lungräddning (HLR) (6ed.). In: Ulf Dahlström, Stergios Kechagias, Leif Stenke (Ed.), Internmedicin: (pp. 229-230). Stockholm: Liber, Sidorna 229-230
Open this publication in new window or tab >>Hjärt- lungräddning (HLR)
2018 (Swedish)In: Internmedicin / [ed] Ulf Dahlström, Stergios Kechagias, Leif Stenke, Stockholm: Liber, 2018, 6, Vol. Sidorna 229-230, p. 229-230Chapter in book (Other academic)
Place, publisher, year, edition, pages
Stockholm: Liber, 2018 Edition: 6
Keywords
Hjärt-lungräddning
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:liu:diva-163175 (URN)9789147113262 (ISBN)
Available from: 2020-01-21 Created: 2020-01-21 Last updated: 2020-01-21Bibliographically approved
Dahlström, U. (2018). Hjärtinsufficiens. In: Ulf Dahlström, Stergios Kechagias, Leif Stenke (Ed.), Internmedicin: (pp. 201-222). Stockholm: Liber, Sidorna 201-222
Open this publication in new window or tab >>Hjärtinsufficiens
2018 (Swedish)In: Internmedicin / [ed] Ulf Dahlström, Stergios Kechagias, Leif Stenke, Stockholm: Liber, 2018, Vol. Sidorna 201-222, p. 201-222Chapter in book (Other academic)
Place, publisher, year, edition, pages
Stockholm: Liber, 2018
Keywords
Hjärtinsufficiens
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:liu:diva-163172 (URN)9789147113262 (ISBN)
Available from: 2020-01-21 Created: 2020-01-21 Last updated: 2020-01-21Bibliographically approved
Dahlström, U. (2018). Hypotension (6ed.). In: Ulf Dahlström, Stergios Kechagias, Leif Stenke (Ed.), Internmedicin: (pp. 230-232). Stockholm: Liber, Sidorna 230-232
Open this publication in new window or tab >>Hypotension
2018 (Swedish)In: Internmedicin / [ed] Ulf Dahlström, Stergios Kechagias, Leif Stenke, Stockholm: Liber, 2018, 6, Vol. Sidorna 230-232, p. 230-232Chapter in book (Other academic)
Place, publisher, year, edition, pages
Stockholm: Liber, 2018 Edition: 6
Keywords
Hypotension
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:liu:diva-163176 (URN)9789147113262 (ISBN)
Available from: 2020-01-21 Created: 2020-01-21 Last updated: 2020-01-21Bibliographically approved
Dahlström, U., Kechagias, S. & Stenke, L. (Eds.). (2018). Internmedicin (6ed.). Stockholm: Liber
Open this publication in new window or tab >>Internmedicin
2018 (English)Collection (editor) (Other academic)
Alternative title[sv]
Med6
Abstract [sv]

Internmedicin beskriver uppkomstmekanismer, förlopp och medicinsk handläggning av den stora grupp sjukdomar som involverar kroppens centrala organsystem, inklusive hjärta-lungor-cirkulation, mage-tarm-lever, benmärg-blod, njurar, rörelseorgan och hormonsekretion.

Internmedicin utkom första gången 1978 och har sedan dess varit en uppskattad kunskapskälla för medicinstuderande under hela utbildningen liksom en oumbärlig uppslagsbok för kliniskt verksamma läkare. I denna sjätte reviderade upplaga är en majoritet av kapitlen nyskrivna eller grundligt uppdaterade. Som tidigare utgörs författarlistan av Sveriges ledande kliniska specialister och forskare inom sina respektive områden. Varje sjukdomstillstånd beskrivs detaljerat med uppgifter om bland annat etiologi, symtom, utredning och behandling. Framställningen är rikt illustrerad, och i varje kapitel belyser man den centrala handläggningen med kliniska patientfall.

Place, publisher, year, edition, pages
Stockholm: Liber, 2018. p. 1046 Edition: 6
Keywords
Internmedicin
National Category
Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-163148 (URN)9789147113262 (ISBN)
Available from: 2020-01-16 Created: 2020-01-16 Last updated: 2020-01-31Bibliographically approved
Dahlström, U. (2018). Ödem (6ed.). In: Ulf Dahlström, Stergios Kechagias, Leif Stenke (Ed.), Internmedicin: (pp. 105-106). Stockholm: Liber, Sidorna 105-106
Open this publication in new window or tab >>Ödem
2018 (Swedish)In: Internmedicin / [ed] Ulf Dahlström, Stergios Kechagias, Leif Stenke, Stockholm: Liber, 2018, 6, Vol. Sidorna 105-106, p. 105-106Chapter in book (Other academic)
Place, publisher, year, edition, pages
Stockholm: Liber, 2018 Edition: 6
Keywords
Ödem
National Category
Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-163171 (URN)9789147113262 (ISBN)
Available from: 2020-01-21 Created: 2020-01-21 Last updated: 2020-01-21Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0001-6353-8041

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