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Hass, Ursula A. M.
Alternative names
Publications (10 of 13) Show all publications
Dahlström, Ö., Timpka, T., Hass, U., Skogh, T. & Thyberg, I. (2008). A simple method for heuristic modeling of expert knowledge in chronic disease: identification of prognostic subgroups in rheumatology. In: eHealth Beyond the Horizon – Get IT There: . Paper presented at 21st International Congress of the European-Federation-for-Medical-Informatic (MIE2008), Gothenburg, Sweden, MAY 25-28, 2008 (pp. 157-162). IOS Press, 136
Open this publication in new window or tab >>A simple method for heuristic modeling of expert knowledge in chronic disease: identification of prognostic subgroups in rheumatology
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2008 (English)In: eHealth Beyond the Horizon – Get IT There, IOS Press, 2008, Vol. 136, p. 157-162Conference paper, Published paper (Refereed)
Abstract [en]

Identification of prognostic subgroups is of key clinical interest at the early stages of chronic disease. The aim of this study is to examine whether representation of physicians' expert knowledge in a simple heuristic model can improve data mining methods in prognostic assessments of patients with rheumatoid arthritis (RA). Five rheumatology consultants' experiences of clinical data patterns among RA patients, as distinguished from healthy reference populations, were formally represented in a simple heuristic model. The model was used in K-mean-clustering to determine prognostic subgroups. Cross-sectional validation using physician's global assessment scores indicated that the simple heuristic model performed better than crude data made in identification of prognostic subgroups of RA patients. A simple heuristic model of experts' knowledge was found useful for semi-automatic data mining in the chronic disease setting. Further studies using categorical baseline data and prospective outcome variables are warranted and will be examined in the Swedish TIRA-program.

Place, publisher, year, edition, pages
IOS Press, 2008
Series
Studies in Health Technology and Informatics, ISSN 0926-9630, E-ISSN 1879-8365 ; Vol. 136
Keywords
Knowledge engineering, Clinical Decision Support Systems, Semiautomated Data Mining, Rheumatoid Arthritis, Mathematical models in medicine
National Category
Social Work
Identifiers
urn:nbn:se:liu:diva-18106 (URN)000274308700026 ()18487724 (PubMedID)978-1-58603-864-9 (ISBN)978-1-60750-333-0 (ISBN)
Conference
21st International Congress of the European-Federation-for-Medical-Informatic (MIE2008), Gothenburg, Sweden, MAY 25-28, 2008
Available from: 2009-05-06 Created: 2009-05-06 Last updated: 2018-04-07Bibliographically approved
Dahlström, Ö., Thyberg, I., Hass, U., Skogh, T. & Timpka, T. (2006). Designing a decision support system for existing clinical organizational structures: Considerations from a rheumatology clinic. Journal of medical systems, 30(5), 325-331
Open this publication in new window or tab >>Designing a decision support system for existing clinical organizational structures: Considerations from a rheumatology clinic
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2006 (English)In: Journal of medical systems, ISSN 0148-5598, E-ISSN 1573-689X, Vol. 30, no 5, p. 325-331Article in journal (Refereed) Published
Abstract [en]

The aim of this study was to identify the social and organizational requirements for a decision support system (DSS) to be implemented in a clinical rheumatology setting, utilizing data-mining techniques. Field observations and focus group interviews were used for data collection. The decision-making was found to be situated, patient-focused, and long-term in nature. At the same time, the main part of peer-to-peer communication was informal. Patient records were involved in almost every decision. The conclusion is that the main challenges, when introducing a DSS at a rheumatology unit, are adapting the system to informal communication structures and integrating it with patient records. Considering incentive structures, understanding workflow and incorporating awareness are relevant issues when addressing these issues in future studies.

National Category
Social Work
Identifiers
urn:nbn:se:liu:diva-18111 (URN)10.1007/s10916-005-9000-1 (DOI)17068995 (PubMedID)
Available from: 2009-05-06 Created: 2009-05-06 Last updated: 2018-04-07Bibliographically approved
Roback, K., Nelson, N., Johansson, A., Hass, U. & Strömberg, T. (2005). A New Fiberoptical Respiratory Rate Monitor for the Neonatal Intensive Care Unit. Pediatric Pulmonology, 39(2), 120-126
Open this publication in new window or tab >>A New Fiberoptical Respiratory Rate Monitor for the Neonatal Intensive Care Unit
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2005 (English)In: Pediatric Pulmonology, ISSN 8755-6863, Vol. 39, no 2, p. 120-126Article in journal (Refereed) Published
Abstract [en]

A new technique for respiratory rate measurement in the neonatal intensive care unit, fiberoptic respirometry (FORE), was tested using a specially designed nasal adapter. The aim was to investigate the system's accuracy and compare it to the transthoracic impedance (TTI) method and manual counting (MC). Further, the relationship between accuracy and degree of body movement was investigated. Seventeen neonates of median gestational age 35 weeks were included in the study. Video recordings (synchronized with data recordings) were used for classification of body movement. Breaths per minute data were obtained for 23-32-min periods per child, and a subset of these included MC performed by experienced nurses. A Bland-Altman analysis showed low accuracy of both FORE and TTI. A >20% deviation from MC was found in 22.7% and 23.8% of observations for the two methods, respectively. Both methods had accuracy problems during body movement. FORE tended to underestimate respiratory rate due to probe displacement, while TTI overestimated due to motion artefacts. The accuracy was also strongly subject-dependent. The neonates were undisturbed by the FORE device. In some cases, though, it was difficult to keep the adapter positioned in the airway. Further development should, therefore, focus on FORE adapter improvements to maintain probe position over time.

Keywords
respiratory rate, neonatal monitoring, prematurity, optical sensors, intensive care, apnea
National Category
Engineering and Technology
Identifiers
urn:nbn:se:liu:diva-14141 (URN)10.1002/ppul.20137 (DOI)
Available from: 2006-11-13 Created: 2006-11-13 Last updated: 2009-05-29
Thyberg , I., Hass, U. A. M., Nordenskiöld, U., Gerdle, B. & Skogh, T. (2005). Activity limitation in rheumatoid arthritis correlates with reduced grip force regardless of sex: The Swedish TIRA project. Arthritis Care and Research, 53(6), 886-896
Open this publication in new window or tab >>Activity limitation in rheumatoid arthritis correlates with reduced grip force regardless of sex: The Swedish TIRA project
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2005 (English)In: Arthritis Care and Research, ISSN 0893-7524, Vol. 53, no 6, p. 886-896Article in journal (Refereed) Published
Abstract [en]

Objective: To evaluate activity limitations 3 years after diagnosis of early rheumatoid arthritis (RA) in relation to grip force and sex.

Methods: A total of 217 patients, 153 women and 64 men, with recent-onset RA were included. Activity limitations were reported using the Health Assessment Questionnaire (HAQ) and the Evaluation of Daily Activities Questionnaire (EDAQ). The relationships between activity limitations versus grip force (measured by the Grippit), walking speed, functional impairment, grip ability, pain, plasma C-reactive protein, the 28-joint disease activity score and its components, the physician's global assessment of disease activity, and sex were analyzed by partial least squares (PLS).

Results: Women had significantly lower grip force and more activity limitations (HAQ and EDAQ) than men. The PLS analyses demonstrated that grip force was the strongest regressor of activity limitation, closely followed by walking speed. However, within subgroups based on grip force (group 1 = grip force <114 N, group 2 = 116-206 N, group 3 = 214-321 N, group 4 = grip force >328 N) and including sexes, women and men had corresponding degrees of activity limitation as reported by the HAQ and EDAQ.

Conclusion: Our results indicate that the more pronounced activity limitations seen in women with RA, as compared with men, may be explained by lower grip force rather than sex.

Place, publisher, year, edition, pages
Wiley InterScience, 2005
Keywords
Activity limitation, Grip force, Health Assessment Questionnaire, Evaluation of Daily Activities Questionnaire, Rheumatoid arthritis, Sex
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-16671 (URN)10.1002/art.21595 (DOI)
Available from: 2009-02-10 Created: 2009-02-10 Last updated: 2015-08-31Bibliographically approved
Thyberg, I., Skogh, T., Hass, U. A. M. & Gerdle, B. (2005). Recent-onset rheumatoid arthritis: A 1-year observational study of correlations between health‐related quality of life and clinical/laboratory data. Journal of Rehabilitation Medicine, 37(3), 159-165
Open this publication in new window or tab >>Recent-onset rheumatoid arthritis: A 1-year observational study of correlations between health‐related quality of life and clinical/laboratory data
2005 (English)In: Journal of Rehabilitation Medicine, ISSN 1650-1977, E-ISSN 1651-2081, Vol. 37, no 3, p. 159-165Article in journal (Refereed) Published
Abstract [en]

Objective: To analyse correlations within and between clinical/laboratory assessments and health-related quality of life variables for recent-onset rheumatoid arthritis at the time of diagnosis and 12 months later.

Methods: A total of 297 patients with recent-onset (?12 months) rheumatoid arthritis were included at diagnosis and followed up for 12 months. Clinical/laboratory assessment was performed by erythrocyte sedimentation rate, C-reactive protein, 28-joint count of tender/swollen joints, physician's global assessment, grip force, grip ability, functional impairment and walking speed. The self-reported health-related quality of life included symptoms (pain, morning stiffness), patients estimated general health, Health Assessment Questionnaire and SF-36.

Results: All tested variables improved within 6 months of diagnosis and then remained stable but still affected at the 12-month follow-up. Multivariate correlations between clinical/laboratory variables and health-related quality of life were weak. At inclusion, clinical/laboratory assessments explained 18% of health-related quality of life at the same time-point and predicted 7% of the variation in health-related quality of life after 12 months.

Conclusion: The time-course followed similar patterns for most variables, but only a small part of the variation in health-related quality of life was explained or predicted by the clinical/laboratory variables. This implies that health-related quality of life adds important information to clinical/laboratory assessments in clinical practice and should be considered in goal setting together with clinical/laboratory assessment in order to optimize healthcare and outcome.

Place, publisher, year, edition, pages
Taylor & Francis, 2005
Keywords
Outcome, early rheumatoid arthritis, health‐related quality of life, HAQ, SF‐36, grip force, walking speed
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-16666 (URN)10.1080/16501970410023344 (DOI)
Available from: 2009-02-10 Created: 2009-02-10 Last updated: 2017-12-14Bibliographically approved
Thyberg, I., Hass, U. A. M., Nordenskiöld , U. & Skogh, T. (2004). A Survey of the use and effect of assistive devices in patients with early rheumatoid arthritis: A two-year followup of women and men. Arthritis Care and Research, 51(3), 413-421
Open this publication in new window or tab >>A Survey of the use and effect of assistive devices in patients with early rheumatoid arthritis: A two-year followup of women and men
2004 (English)In: Arthritis Care and Research, ISSN 0893-7524, E-ISSN 1529-0123, Vol. 51, no 3, p. 413-421Article in journal (Refereed) Published
Abstract [en]

Objective: To identify activity limitation in early rheumatoid arthritis (RA) to detect patients needing assistive devices. To evaluate the effects of assistive devices.

Methods: A multicenter cohort of 284 early RA patients was examined using the Evaluation of Daily Activity Questionnaire 12 and 24 months after diagnosis.

Results: The extent of activity limitation was stable over time for both women and men. Most limitations concerned eating and drinking. Women reported more difficulties than did men. The use of assistive devices was related to subgroups with severe disease and more disability. Use of assistive devices reduced difficulties significantly. For both women and men, assistive devices were mostly used in activities related to eating and drinking.

Conclusion: Already 1 year after diagnosis, RA patients reported activity limitation that remained stable over time. Use of assistive devices was related to more severe disease and more pronounced disability. Use of devices reduced difficulties significantly.

Place, publisher, year, edition, pages
Wiley InterScience, 2004
Keywords
Assistive devices, Early rheumatoid arthritis, Activity limitation, Sex
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-16668 (URN)10.1002/art.20410 (DOI)
Available from: 2009-02-10 Created: 2009-02-10 Last updated: 2017-12-14Bibliographically approved
Hallert, E., Thyberg, I., Hass, U., Skargren, E. & Skogh, T. (2003). Comparison between women and men with recent onset rheumatoid arthritis of disease activity and functional ability over two years (the TIRA project). Annals of the rheumatic diseases, 62, 667-670
Open this publication in new window or tab >>Comparison between women and men with recent onset rheumatoid arthritis of disease activity and functional ability over two years (the TIRA project)
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2003 (English)In: Annals of the rheumatic diseases, ISSN 0003-4967, Vol. 62, p. 667-670Article in journal (Refereed) Published
Abstract [en]

Objective: To describe the course of recent onset rheumatoidarthritis (RA) and to compare consequences of the disease inmen and women.

Methods: 284 patients with recent onset RA were followed upprospectively for two years from the time of diagnosis. Measuresof disease activity (for example, 28 joint disease activityscore (DAS28), C reactive protein, morning stiffness, physician’sglobal assessment) and function outcome (for example, rangeof movement, hand function, walking time) were determined. Thepatients’ self reported assessment of functional capacity(Health Assessment Questionnaire (HAQ)) and grading of wellbeingand pain (visual analogue scale) were registered. Changes overtime and differences between men and women were evaluated.

Results: Improvements were seen for all variables within thefirst three months. Disease activity then remained unchanged.Function variables followed the same pattern during the firstyear, but then tended to worsen. HAQ scores were similar atbaseline, but significantly worse in women than in men at theone and two year follow ups.

Conclusions: Disease activity was well managed and had improvedsubstantially after two years, whereas function seemed slowlyto deteriorate. Although disease variables were similar formen and women, functional ability (HAQ) had a less favourablecourse in women.

Keywords
early rheumatoid arthritis, outcome, disability, sex
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-14282 (URN)
Available from: 2007-02-01 Created: 2007-02-01 Last updated: 2015-08-31
Roback, K., Persson, J. & Hass, U. (2003). Spridning och implementering av medicintekniska produkter: Bakgrundsrapport. Linköping: Linköpings universitet
Open this publication in new window or tab >>Spridning och implementering av medicintekniska produkter: Bakgrundsrapport
2003 (Swedish)Report (Other academic)
Place, publisher, year, edition, pages
Linköping: Linköpings universitet, 2003
Series
CMT rapport ; 1
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-41586 (URN)58013 (Local ID)58013 (Archive number)58013 (OAI)
Available from: 2009-10-10 Created: 2009-10-10
Roback, K., Hass, U. & Persson, J. (2001). Transfer of health care technology in university-industry research collaboration environment. In: Engineering in Medicine and Biology Society. Proceedings of the 23rd Annual International Conference of the IEEE: (pp. 3938-3941). , 4
Open this publication in new window or tab >>Transfer of health care technology in university-industry research collaboration environment
2001 (English)In: Engineering in Medicine and Biology Society. Proceedings of the 23rd Annual International Conference of the IEEE, 2001, Vol. 4, p. 3938-3941Conference paper, Published paper (Refereed)
Abstract [en]

The traditional innovation research has focused on the diffusion process and adoption of new technologies. This paper deals with health care technology in the early innovation stages preceding targeted development and marketing. A model of early research processes in the biomedical field and determinants of technology transfer will be presented. The study material is eleven projects in the Competence Center Noninvasive Medical Measurements (NIMED), Linkoping University, which is a collaboration center where academic researchers cooperate with industry and clinical departments. Data collection was made through semi-structured interviews. A qualitative approach has been adopted for data analysis. Research initiatives of the investigated projects do in most cases originate in the academic knowledge base and earlier connections in industry and health care play an important role in the formation of cooperation constellation. A number of internal factors are perceived as positive to project advancement, such as stable economy, proximity to clinical departments, and positive feedback from collaboration partners. Significant negative factors are all related to changes in cooperation structure. Clusters of related projects seem to be beneficial to research work and is an evident external factor which has to be added in a new model of technology transfer.

National Category
Medical Laboratory and Measurements Technologies
Identifiers
urn:nbn:se:liu:diva-14140 (URN)
Available from: 2006-11-13 Created: 2006-11-13
Hass, U., Ask, P. & Wårdell, K. (1999). Competence Centre NIMED and it's graduate education - collaboration between university and industry.. In: Ann Int Conf of the IEEE Engineering in Medicine and Biology Society,1999.
Open this publication in new window or tab >>Competence Centre NIMED and it's graduate education - collaboration between university and industry.
1999 (English)In: Ann Int Conf of the IEEE Engineering in Medicine and Biology Society,1999, 1999Conference paper, Published paper (Other academic)
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-29739 (URN)15138 (Local ID)15138 (Archive number)15138 (OAI)
Available from: 2009-10-09 Created: 2009-10-09 Last updated: 2016-05-04
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