liu.seSearch for publications in DiVA
Change search
Link to record
Permanent link

Direct link
BETA
Nilsson, David
Alternative names
Publications (10 of 28) Show all publications
Toss, H., Lönnqvist, S., Nilsson, D., Sawatdee, A., Nissa, J., Fabiano, S., . . . Simon, D. T. (2017). Ferroelectric Surfaces for Cell Release. Synthetic metals, 228, 99-104
Open this publication in new window or tab >>Ferroelectric Surfaces for Cell Release
Show others...
2017 (English)In: Synthetic metals, ISSN 0379-6779, E-ISSN 1879-3290, Vol. 228, p. 99-104Article in journal (Refereed) Published
Abstract [en]

Adherent cells cultured in vitro must usually, at some point, be detached from the culture substrate. Presently, the most common method of achieving detachment is through enzymatic treatment which breaks the adhesion points of the cells to the surface. This comes with the drawback of deteriorating the function and viability of the cells. Other methods that have previously been proposed include detachment of the cell substrate itself, which risks contaminating the cell sample, and changing the surface energy of the substrate through thermal changes, which yields low spatial resolution and risks damaging the cells if they are sensitive to temperature changes. Here cell culture substrates, based on thin films of the ferroelectric polyvinylidene fluoride trifluoroethylene (PVDF-TrFE) co-polymer, are developed for electroactive control of cell adhesion and enzyme-free detachment of cells. Fibroblasts cultured on the substrates are detached through changing the direction of polarization of the ferroelectric substrate. The method does not affect subsequent adhesion and viability of reseeded cells.

Place, publisher, year, edition, pages
Elsevier, 2017
National Category
Physical Sciences Electrical Engineering, Electronic Engineering, Information Engineering Clinical Science
Identifiers
urn:nbn:se:liu:diva-121804 (URN)10.1016/j.synthmet.2017.04.013 (DOI)000401599600015 ()
Note

Funding agencies: Swedish Governmental Agency for Innovation Systems (VINNOVA) [2010-00507]; Knut and Alice Wallenberg Foundation; Onnesjo Foundation

Available from: 2015-10-07 Created: 2015-10-07 Last updated: 2018-04-13Bibliographically approved
Isaksson, J., Nilsson, D., Kjäll, P., Robinson, N., Richter-Dahlfors, A. & Berggren, M. (2008). Electronically Controlled pH Gradients and Proton Oscillations. Organic electronics, 9(3), 303-309
Open this publication in new window or tab >>Electronically Controlled pH Gradients and Proton Oscillations
Show others...
2008 (English)In: Organic electronics, ISSN 1566-1199, E-ISSN 1878-5530, Vol. 9, no 3, p. 303-309Article in journal (Refereed) Published
Abstract [en]

An organic electronic ion pump, including poly(3,4-ethylenedioxythiophene) as the active material has been used to electronically control the transport of protons between two electrolytes and to change the pH of the target solution from 7 to 3 in a few minutes. The number of transported protons equals the time-integrated current between the two addressing electrodes. If no voltage is applied the leakage due to diffusion is not detectable, which indicates an overall proton delivery on/off ratio exceeding 1000. Locally, the pH drop can be even larger and the relationship between the proton delivery rate of the pump and proton diffusion in the electrolyte forms pH gradients. If the device is instead addressed with short pulses, local pH oscillations are created. The transport of protons presented here can be extended to other small sized ions, which in combination with the biocompatibility of the delivery surface make the device promising for cell communication studies and lab-on-a-chip applications.

Keywords
Conjugated polymer, Electronic ion pump, Ion oscillations, pH
National Category
Engineering and Technology
Identifiers
urn:nbn:se:liu:diva-14645 (URN)10.1016/j.orgel.2007.11.011 (DOI)
Available from: 2008-11-12 Created: 2008-11-12 Last updated: 2017-12-13
Isaksson, J., Kjäll, P., Nilsson, D., Robinson, N., Berggren, M. & Richter-Dahlfors, A. (2007). Electronic Control of Ca2+ Signalling in Neuronal Cells using an Organic Electronic Ion Pump. Nature Materials, 6(9), 673-679
Open this publication in new window or tab >>Electronic Control of Ca2+ Signalling in Neuronal Cells using an Organic Electronic Ion Pump
Show others...
2007 (English)In: Nature Materials, ISSN 1476-1122, Vol. 6, no 9, p. 673-679Article in journal (Refereed) Published
Abstract [en]

Cells and tissues use finely regulated ion fluxes for their intra- and intercellular communication. Technologies providing spatial and temporal control for studies of such fluxes are however, limited. We have developed an electrophoretic ion pump made of poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulphonate) (PEDOT:PSS) to mediate electronic control of the ion homeostasis in neurons. Ion delivery from a source reservoir to a receiving electrolyte via a PEDOT:PSS thin-film channel was achieved by electronic addressing. Ions are delivered in high quantities at an associated on/off ratio exceeding 300. This induces physiological signalling events that can be recorded at the single-cell level. Furthermore, miniaturization of the device to a 50-um-wide channel allows for stimulation of individual cells. As this technology platform allows for electronic control of ion signalling in individual cells with proper spatial and temporal resolution, it will be useful in further studies of communication in biological systems.

National Category
Engineering and Technology
Identifiers
urn:nbn:se:liu:diva-14644 (URN)10.1038/nmat1963 (DOI)
Available from: 2008-11-12 Created: 2008-11-12 Last updated: 2017-02-03
Berggren, M., Nilsson, D. & Robinson, N. D. (2007). Organic materials for printed electronics. Nature Materials, 6(1), 3-5
Open this publication in new window or tab >>Organic materials for printed electronics
2007 (English)In: Nature Materials, ISSN 1476-1122, E-ISSN 1476-4660, Vol. 6, no 1, p. 3-5Article in journal (Refereed) Published
Abstract [en]

Organic materials can offer a low-cost alternative for printed electronics and flexible displays. However, research in these systems must exploit the differences — via molecular-level control of functionality — compared with inorganic electronics if they are to become commercially viable.

Introduction

Conducting and semiconducting organic materials, both polymers and molecules, are being considered for a vast array of electronic applications. The first examples, such as displays in mobile appliances, have found their way to market as replacements for traditional components in existing products. Organic electronics distinguishes itself from traditional electronics because one can define functionality at the molecular level, process the materials from solution, and make displays and circuits that are completely flexible. So far, very little of the uniqueness of organic electronics is expressed in the products promoted as manufacturable; why?

One important opportunity for organic electronics is the area of radiofrequency identification (RFID) manufactured using an all-in-line printing process. This technology comprises fast-switching transistors, antennas operating at frequencies above 100 kHz, memory, and so on, all integrated into a plastic foil. The present target in many organic electronics labs around the world is to develop the high-speed (>10 kHz) transistors critical for such devices. The use of organic transistors instead of their inorganic equivalents is motivated by cost. So far, little effort has been devoted to exploring organic electronics in terms of its true unique electronic functionality and the possibility to add electronics to surfaces previously considered electronically inactive. For instance, paper is produced at speeds exceeding 100 km h-1 and is converted into packages and printed media at manufacturing flows typically above 100 m min-1. Adding organic electronics onto, for instance, the paper surface during the paper conversion process would demonstrate the true uniqueness of organic electronics, both from a manufacturing and an application point of view. Retail chains and transportation companies desperately seek a printed electronic technology to provide better safety and security features on packages and automatically track and trace products all the way from the manufacturer to the end customer. The financial losses related to counterfeiting, failure in transportation and damaged packages is comparable to the overall profits made on the product contained in the package. In addition, printed electronics could potentially guide the end-user to properly use the product and to guarantee brand authenticity, for example through an interactive user's guide, and electronic features to replace existing security devices such as the holographic stickers commonly used in packages and bank notes today. It turns out that, for many of these applications, high-frequency signal-processing is not required; 10 ms to 1 s response times are appropriate. These are goals that a very simple printed electronics technology may be able to fill. Silicon-based RFID devices are currently used in high-end products, but are prohibitively expensive for commodities such as food at the consumer package level. Thus, the potential value for printed organic electronics seems to exist if the expense can be kept down. For instance, TetraPak, who produces more than 100 billion packages every year, estimates that the costs for additional security and safety features cannot exceed about 0.2 Eurocents per package (Istvan Ulvros, TetraPak, private communication).

Much of the research in organic electronics aims to optimise inherent charge transport and efficiency characteristics of the materials already in use in individual devices. This work has pushed the solar energy-to-electricity power-conversion efficiency in organic solar cells close to 5% (ref. 1) and the luminous efficiency of plastic luminescent devices to around 25 cd A-1 (ref. 2). Organic electrochromic displays now perform extraordinarily well in terms of colour contrast, memory and stability3, and polymer transistors easily run at speeds beyond 100 kHz (ref.4). These results have been achieved by improving the performance at the individual device level. Rarely are integrated circuits or high-volume manufacturing conditions considered in the research. Typically, a series of more than ten patterning, material deposition and post-processing steps are required to make one kind of device. The tradition has been to develop specific materials that exclusively function well in only one device type. RFID circuits (for example) typically require rectifiers, antennas, powering devices, transistors for signal processing, encapsulation layers and in some cases also displays. Merging today's efforts conducted at the organic electronics device level would then result in a production route that would include perhaps 50 (or even more) discrete manufacturing steps. Unfortunately, the cost for a label requiring several tens of patterning steps including exotic organic electronic materials is not compatible with the value and costs of packages.

In traditional printers, typically five to ten printing stations are available in series (Fig. 1). Each station also includes one or two convection, infrared or ultraviolet curing steps. At ordinary printing speeds (10 to 200 m min-1) the substrate spends on the order of a tenth to several seconds in each printing station. During this time, registration, material deposition and post-processing must take place. The value structure in printing technology means that the cost for printing scales at least linearly with the number of printing steps. The yield and systematic errors in printing technology becomes a nightmare beyond ten printing steps. The cost for materials such as inks, substrates and coatings is a considerable part of the entire product value. Our own calculations indicate that each individual RFID label would cost more than 10 Eurocents (Lars-Olov Hennerdal, Acreo, private communication).

National Category
Natural Sciences
Identifiers
urn:nbn:se:liu:diva-75589 (URN)10.1038/nmat1817 (DOI)
Available from: 2012-03-09 Created: 2012-03-09 Last updated: 2017-12-07
Robinson, N. D., Svensson, P.-O., Nilsson, D. & Berggren, M. (2006). On the Current Saturation Observed in Electrochemical Polymer Transistors. Journal of the Electrochemical Society, 153, 39-44
Open this publication in new window or tab >>On the Current Saturation Observed in Electrochemical Polymer Transistors
2006 (English)In: Journal of the Electrochemical Society, ISSN 0013-4651, E-ISSN 1945-7111, Vol. 153, p. 39-44Article in journal (Refereed) Published
Abstract [en]

Electrochemical transistors based on conjugated polymers are proposed as a path to printed electronics on paper. The electrochemical doping/dedoping of conjugated polymers clearly plays a role in the current vs potential (I-V) characteristics of these devices, however, the mechanism of current saturation (often referred to as pinch-off) is not clearly understood, and the relationship between electrochemical devices and field-effect transistors is unclear. This paper offers a semiempirical model of the steady-state behavior of electrochemical transistors and compares this model with experimental observations of potential and electrochromic measurements within a device to illustrate the science behind the functionality observed. ©2006 The Electrochemical Society

Keywords
electrochemical devices; transistors; conducting polymers; organic semiconductors; semiconductor doping
National Category
Engineering and Technology
Identifiers
urn:nbn:se:liu:diva-32350 (URN)10.1149/1.2172534 (DOI)18245 (Local ID)18245 (Archive number)18245 (OAI)
Available from: 2009-10-09 Created: 2009-10-09 Last updated: 2017-12-13
Andersson, P., Tehrani, P., Forchheimer, R., Nilsson, D., Robinson, N. D. & Berggren, M. (2005). All-Organic Active Matrix Addressed Displays Based on Electrochromic Polymers and Flexible Substrate. In: MRS Fall Meeting,2005.
Open this publication in new window or tab >>All-Organic Active Matrix Addressed Displays Based on Electrochromic Polymers and Flexible Substrate
Show others...
2005 (English)In: MRS Fall Meeting,2005, 2005Conference paper, Published paper (Refereed)
National Category
Engineering and Technology
Identifiers
urn:nbn:se:liu:diva-32391 (URN)18291 (Local ID)18291 (Archive number)18291 (OAI)
Available from: 2009-10-09 Created: 2009-10-09 Last updated: 2017-02-03
Nilsson, D. (2005). An Organic Electrochemical Transistor for Printed Sensors and Logic. (Doctoral dissertation). : Institutionen för teknik och naturvetenskap
Open this publication in new window or tab >>An Organic Electrochemical Transistor for Printed Sensors and Logic
2005 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Conducting polymers entered the research field in late 70´s and efforts aimed at achieving printed electronics started a decade later. This thesis treats printable organic electrochemical transistors (OECT). Some conjugated polymers can be switched between a high conducting and a low conducting state in an electrochemical cell. In this thesis, the work carried out using poly(3,4-ethylenedioxythiophene) (PEDOT) as the active material in an electrochemical transistor is reported. The electrochemical transistors, presented, can be designed into a bi-stable and dynamic mode of operation. These transistors operates at voltages below 2V and current on/off ratios are typically 5000, but 105 have been reached. The transistor device can be built up from all-organic materials using common printing techniques such as with screen-printing. The bi-stable transistor can be combined with an electrochromic (EC) display cell to form a smart pixel circuit. Combining several of these smart pixels yield an actively addressed cross-point matrix display. From this an all-organic active matrix display printable on paper has been achieved. The OECT, combined with a resistor network was successfully used in inverter and logic circuits.

One important feature of these organic electrochemical devices is that both ions and electrons are used as the charge (signal) carriers. This is of particular interest and importance for chemical sensors. By combining a proton-conducting electrolyte (Nafion®) that changes its conductivity upon exposure to humidity, a simple OECT humidity sensor was achieved. This proves the use of this OECT as the ion-to-electron transducer.

Place, publisher, year, edition, pages
Institutionen för teknik och naturvetenskap, 2005
Series
Linköping Studies in Science and Technology. Dissertations, ISSN 0345-7524 ; 921
Keywords
printable organic electrochemical transistors (OECT), polymers, charge (signal) carriers, proton-conducting electrolyte (Nafion)
National Category
Organic Chemistry
Identifiers
urn:nbn:se:liu:diva-5024 (URN)91-85297-26-7 (ISBN)
Public defence
2005-02-17, K3, Kåkenhus, Campus Norrköping, Linköpings universitet, Linköping, 10:00 (English)
Opponent
Supervisors
Available from: 2005-03-10 Created: 2005-03-10 Last updated: 2017-02-03
Nilsson, D., Robinson, N., Berggren, M. & Forchheimer, R. (2005). Electrochemical Logic Circuits. Advanced Materials, 17(3), 353-358
Open this publication in new window or tab >>Electrochemical Logic Circuits
2005 (English)In: Advanced Materials, ISSN 0935-9648, Vol. 17, no 3, p. 353-358Article in journal (Refereed) Published
Keywords
Logic gates, organic, Transistors, electrochemical
National Category
Engineering and Technology
Identifiers
urn:nbn:se:liu:diva-13563 (URN)10.1002/adma.200401273 (DOI)
Available from: 2008-11-12 Created: 2008-11-12 Last updated: 2017-02-03
Robinson, N. D., Svensson, P.-O., Nilsson, D. & Berggren, M. (2005). Electrochromism as a tool for understanding the electrochemical polymer transistor. In: MRS Fall Meeting,2005.
Open this publication in new window or tab >>Electrochromism as a tool for understanding the electrochemical polymer transistor
2005 (English)In: MRS Fall Meeting,2005, 2005Conference paper, Published paper (Refereed)
National Category
Engineering and Technology
Identifiers
urn:nbn:se:liu:diva-32388 (URN)18288 (Local ID)18288 (Archive number)18288 (OAI)
Available from: 2009-10-09 Created: 2009-10-09 Last updated: 2017-02-03
Berggren, M., Hennerdal, L.-O., Nilsson, D., Sawatdee, A., Forchheimer, R. & Robinson, N. D. (2005). Printed Integrated Electronic and Electrochemical Systems on Paper. In: MRS Fall Meeting,2005.
Open this publication in new window or tab >>Printed Integrated Electronic and Electrochemical Systems on Paper
Show others...
2005 (English)In: MRS Fall Meeting,2005, 2005Conference paper, Published paper (Refereed)
National Category
Engineering and Technology
Identifiers
urn:nbn:se:liu:diva-32387 (URN)18287 (Local ID)18287 (Archive number)18287 (OAI)
Available from: 2009-10-09 Created: 2009-10-09 Last updated: 2017-02-03
Organisations

Search in DiVA

Show all publications