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Lyth, Johan
Publications (10 of 19) Show all publications
Lyth, J., Lind, L., Karlsson, D., Persson, L. H. & Wiréhn, A.-B. (2018). Can a telemonitoring system lead to decreased hospital admissions in elderly patients?. In: : . Paper presented at ERS International Congress 2018, Paris, France, 15-19 September, 2018.
Open this publication in new window or tab >>Can a telemonitoring system lead to decreased hospital admissions in elderly patients?
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2018 (English)Conference paper, Oral presentation with published abstract (Refereed)
Abstract [en]

Background: Populations of elderly patients with chronic obstructive pulmonary disease (COPD) or heart failure (HF) are growing. To prevent exacerbations leading to inpatient care, a 4 year (2013-2017) telehealth intervention non-randomized single-centre clinical study was performed. We hypothesized that the patients, grouped by advanced COPD or HF, would exhibit decreased need of hospital admissions.

Objective: To study hospital admissions in patients with COPD or HF using a telemonitoring system, the Health Diary.

Methods: A telemonitoring system, the Health Diary, based on digital pen technology, was employed. Patients with COPD or HF treated at the University Hospital in Linköping were included if they had at least 2 hospital admissions the previous year. Data on hospital admissions was obtained from the administrative healthcare database. Expected number of hospital admissions for the study year was calculated using 5-year data for a group of patients with matching diagnosis and history of hospital admissions and was compared to the actual value in the intervention group using Poisson regression.

Results: Together with the included patients, 159 HF and 136 COPD non-intervention patients was used to calculate the expected values for hospital admissions. For the 58 included HF patients, the average number of hospital admissions of 0.81 was 32.8 percent (p=0.04) lower than expected. For the 36 included COPD patients, the average number of hospital admissions of 1.44 was 37.0 percent (p=0.02) lower than expected.

Conclusions: Use of the telemonitoring system, the Health Diary, decreases hospital admissions in elderly with COPD and HF.

National Category
Respiratory Medicine and Allergy
Identifiers
urn:nbn:se:liu:diva-153784 (URN)10.1183/13993003.congress-2018.PA1998 (DOI)
Conference
ERS International Congress 2018, Paris, France, 15-19 September, 2018
Available from: 2019-01-10 Created: 2019-01-10 Last updated: 2019-01-17Bibliographically approved
Lyth, J. (2018). Conditional recurrence-free survival in patients with primary stage I-II cutaneous malignant melanoma - a population-based study. Melanoma research, 28(6), 637-640
Open this publication in new window or tab >>Conditional recurrence-free survival in patients with primary stage I-II cutaneous malignant melanoma - a population-based study
2018 (English)In: Melanoma research, ISSN 0960-8931, E-ISSN 1473-5636, Vol. 28, no 6, p. 637-640Article in journal (Refereed) Published
Abstract [en]

Conditional survival in patients with localized primary cutaneous malignant melanoma (CMM) is well described. However, conditional recurrence-free survival (RFS) has not been investigated before. The aim of this study was to determine conditional RFS and test for time dependency in prognostic factors in patients with localized stage I-II CMM. This study included 1437 CMM patients registered in one region of Sweden during 1999-2012 followed up through 31 December 2012. To identify first recurrence of CMM disease, data from a care data warehouse, the pathology and radiology department registries were used. Patients were also followed through a Census Register and the National Cause of Death Register. The time-dependent risk of recurrence was analysed in a Coxs proportional hazard regression. The 5-year conditional RFS increased from 86% (95% confidence interval: 84-88) at diagnosis to 96% (95% confidence interval: 94-98) at 5 years after diagnosis. Women showed a 60% lower risk of recurrence than men and this effect was stable over time (P = 0.39). Patients aged greater than or equal to 65 years had a 40% higher risk of recurrence than patients aged less than 65 years, and this effect was stable over time (P = 0.65). Patients with tumour ulceration showed a 70% higher risk of recurrence than nonulcerated patients, but this effect disappeared after 2 years (P = 0.04). For patients with T3-T4 CMM, the hazard ratios decreased over time and were similar to hazard ratio of patients with T2 CMM after 2 years and later. The decreasing impact of tumour thickness and ulceration over time could have important implications for CMM patients in terms of counselling and follow-up. Copyright (C) 2018 Wolters Kluwer Health, Inc. All rights reserved.

Place, publisher, year, edition, pages
LIPPINCOTT WILLIAMS & WILKINS, 2018
Keywords
conditional survival; malignant melanoma; melanoma recurrence; metastases; population based
National Category
Surgery
Identifiers
urn:nbn:se:liu:diva-153158 (URN)10.1097/CMR.0000000000000479 (DOI)000449641700020 ()29994850 (PubMedID)
Available from: 2018-12-01 Created: 2018-12-01 Last updated: 2019-05-01
Lind, L., Lyth, J., Karlsson, D. M. G., Wiréhn, A.-B. & Persson, L. (2018). COPD patients require more health care than heart failure patients. In: ERS International Congress 2018: . Paper presented at ERS International Congress 2018, Paris, France, 15-19 September, 2018.
Open this publication in new window or tab >>COPD patients require more health care than heart failure patients
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2018 (English)In: ERS International Congress 2018, 2018Conference paper, Oral presentation with published abstract (Refereed)
Abstract [en]

Background: Populations of elderly patients with advanced stages of chronic obstructive pulmonary disease (COPD) or heart failure (HF) are growing, urging the need for specialized health care in the patients’ home. A 4 year (2013-2017) telehealth intervention single-centre clinical study has been completed. We hypothesized that the two groups of patients, advanced COPD or HF, would exhibit differences regarding exacerbations and the need of health care.

Objective: To study exacerbations of COPD or HF, and patients’ need of health care.

Methods: A telemonitoring system, the Health Diary, which is based on digital pen technology, was employed. Patients with at least 2 hospital admissions the previous year were included. Responsible nurses and physicians at a specialized home care unit at a university hospital checked all daily patient reports. Physicians identified exacerbations using information provided through the telemonitoring system and patient contacts. Consumed health care was assessed as the number of patient contacts (home visits or telephone consultations).

Results: Totally, 94 patients with advanced disease were enrolled (36 COPD and 58 HF patients) of which 53 patients (19 COPD and 34 HF patients) completed the 1-yr study period. The major reason for not completing the study was death (13 COPD, 15 HF patients). Average numbers of exacerbations were 3.1 and 0.8 and patient contacts were 94 and 67 per COPD and HF patient, respectively.

Conclusions: Compared to HF patients, COPD patients exhibit exacerbations more frequently and demand much more home health care. This difference of health care consumption is mainly due to disease characteristics.

National Category
Respiratory Medicine and Allergy
Identifiers
urn:nbn:se:liu:diva-153785 (URN)10.1183/13993003.congress-2018.PA743 (DOI)
Conference
ERS International Congress 2018, Paris, France, 15-19 September, 2018
Available from: 2019-01-10 Created: 2019-01-10 Last updated: 2019-01-17
Utjes, D., Lyth, J., Lapins, J. & Eriksson, H. (2017). Reduced disease-specific survival following a diagnosis of multiple primary cutaneous malignant melanomas-a nationwide, population-based study. International Journal of Cancer, 141(11), 2243-2252
Open this publication in new window or tab >>Reduced disease-specific survival following a diagnosis of multiple primary cutaneous malignant melanomas-a nationwide, population-based study
2017 (English)In: International Journal of Cancer, ISSN 0020-7136, E-ISSN 1097-0215, Vol. 141, no 11, p. 2243-2252Article in journal (Refereed) Published
Abstract [en]

Outcome data comparing patients with multiple primary invasive cutaneous malignant melanomas (MPMs) to single primary invasive cutaneous malignant melanomas (SPMs) show conflicting results. We have analyzed differences in disease-specific survival between these patients in a nationwide population-based setting. From the Swedish Melanoma Register, 27,235 patients were identified with a first invasive cutaneous malignant melanoma (CMM) between 1990 and 2007, followed-up through 2013. Of these, 700 patients developed MPMs. Cox proportional hazard regression was used for adjusted cause-specific hazard ratios (HRs). An interval of amp;lt;= 5 years between CMM diagnoses was significantly correlated to a decreased CMM-specific survival in Stage I-II MPM-vs. SPM-patients (HR 1.32; 95% CI 1.04-1.67; p=0.02). MPM-patients with longer time interval between diagnoses experienced similar risk of CMM-death as SPM-patients. The risk of CMM-death increased by almost 50% above the expected outcome according to stage of the index CMM by the diagnosis of a second CMM (HR 1.48; 95% CI 1.19-1.85; p amp;lt; 0.001). MPM vs. SPM-patients had a worse outcome (HR 1.38; 95% CI 1.05-1.83; p=0.001). This emphasizes the importance of prevention efforts in SPM-patients to decrease the risk of subsequent CMMs and has implications for more vigilant follow-up in MPM-patients.

Place, publisher, year, edition, pages
WILEY, 2017
Keywords
cutaneous malignant melanoma; multiple melanomas; disease-specific survival; interval-time; population-based
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:liu:diva-142134 (URN)10.1002/ijc.30925 (DOI)000412473600008 ()28799271 (PubMedID)
Note

Funding Agencies|Swedish Cancer Society [CAN 2010/225, CAN 2011/883]; Radiumhemmet Research Funds [124083, 124092]; Sigurd and Elsa Goljes Memorial Foundation [LA2016-0389]; KI funds [2016fobi50190]

Available from: 2017-10-24 Created: 2017-10-24 Last updated: 2018-05-03
Simberg-Danell, C., Lyth, J., Mansson-Brahme, E., Frohm-Nilsson, M., Carstensen, J., Hansson, J. & Eriksson, H. (2016). Prognostic factors and disease-specific survival among immigrants diagnosed with cutaneous malignant melanoma in Sweden. International Journal of Cancer, 139(3), 543-553
Open this publication in new window or tab >>Prognostic factors and disease-specific survival among immigrants diagnosed with cutaneous malignant melanoma in Sweden
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2016 (English)In: International Journal of Cancer, ISSN 0020-7136, E-ISSN 1097-0215, Vol. 139, no 3, p. 543-553Article in journal (Refereed) Published
Abstract [en]

Little is known about cutaneous malignant melanoma (CMM) among immigrants in Europe. We aimed to investigate clinical characteristics and disease-specific survival among first-and second-generation immigrants in Sweden. This nationwide population-based study included 27,235 patients from the Swedish Melanoma Register diagnosed with primary invasive CMM, 1990-2007. Data were linked to nationwide, population-based registers followed up through 2013. Logistic regression and Cox regression models were used to determine the association between immigrant status, stage and CMM prognosis, respectively. After adjustments for confounders, first generation immigrants from Southern Europe were associated with significantly more advanced stages of disease compared to Swedish-born patients [Stage II vs. I: Odds ratio (OR) = 2.37, 95% CI = 1.61-3.50. Stage III-IV vs I: OR=2.40, 95% CI = 1.08-5.37]. The ORs of stage II-IV versus stage I disease were increased among men (OR = 1.9; 95% CI = 1.1-3.3; p = 0.020), and women (OR = 4.8; 95% CI = 2.6-9.1; pamp;lt;0.001) in a subgroup of immigrants from former Yugoslavia compared to Swedish-horn patients. The CMM-specific survival was significantly decreased among women from former Yugoslavia versus Swedish-born women [hazard ratio (HR)=2.2; 95 h CI = 1.1-4.2; p = 0.043]. After additional adjustments including stage, the survival difference was no longer significant. No survival difference between the second generation immigrant group and Swedish-born patients were observed. In conclusion, a worse CMM-specific survival in women from former Yugoslavia was associated with more advanced stages of CMM at diagnosis. Secondary prevention efforts focusing on specific groups may be needed to further improve the CMM prognosis.

Place, publisher, year, edition, pages
WILEY-BLACKWELL, 2016
Keywords
cutaneous malignant melanoma; population-based; prognosis; immigrants; nationwide
National Category
Cancer and Oncology
Identifiers
urn:nbn:se:liu:diva-130258 (URN)10.1002/ijc.30103 (DOI)000378418100007 ()27004457 (PubMedID)
Note

Funding Agencies|Swedish Cancer Society [CAN 2010/225, CAN 2011/883]; Radiumhemmet Research [124083, 124092]; Sigurd and Elsa Golijes Memorial Foundation [LA2012-0112]; Stockholm County Council [20100032]

Available from: 2016-08-01 Created: 2016-07-28 Last updated: 2017-05-03
Lyth, J., Mikiver, R., Nielsen, K., Isaksson, K. & Ingvar, C. (2016). Prognostic instrument for survival outcome in melanoma patients: based on data from the population-based Swedish Melanoma Register. European Journal of Cancer, 59, 171-178
Open this publication in new window or tab >>Prognostic instrument for survival outcome in melanoma patients: based on data from the population-based Swedish Melanoma Register
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2016 (English)In: European Journal of Cancer, ISSN 0959-8049, E-ISSN 1879-0852, Vol. 59, p. 171-178Article in journal (Refereed) Published
Abstract [en]

Background: Several major analyses have identified a consistent set of independent risk factors for cutaneous malignant melanoma (CMM). A few prognostic models have been presented but some are based on a limited number of patients and others are based on selected groups of patients referred to major institutions. No nationwide population-based prognostic instrument for survival of CMM has been presented. The Swedish Melanoma Register (SMR) database covers 99% of CMM diagnosed in Sweden and includes today >50,000 cases. Objectives: To create a prognostic instrument based on SMR data to give highly reliable risk profiles for patients diagnosed with localised CMM. Methods: Clinicopathological data were linked to the cause of death registry for calculation of CMM-specific survival. A generalised gamma method was used to derive 1, 5 and 10year probabilities of death for each combination of patient and tumour data: age, sex, tumour site, tumour thickness, tumour ulceration, Clarks level of invasion and when applicable also outcome of sentinel node biopsy (SNB). Results: Tumour thickness had the highest prognostic impact, explaining 77% of the model. Women had 30% lower risk of death because of CMM than men. Presence of ulceration nearly doubled the risk. If the patient had a positive SNB status the risk of death due to CMM increased three times versus a negative SNB status. Conclusion: This unique population-based prognostic model for primary CMM shows better survival than the American Joint Commission on Cancer prognostic model widely used. The reason is probably that the referral bias is eliminated in a population-based cohort.

Place, publisher, year, edition, pages
ELSEVIER SCI LTD, 2016
Keywords
Prognostic instrument; Malignant melanoma; Population-based; Generalised gamma method
National Category
Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-128735 (URN)10.1016/j.ejca.2016.02.029 (DOI)000375138200019 ()27046697 (PubMedID)
Note

Funding Agencies|Regional Cancer Centre South East in Linkoping; Hudfonden; S.R Gorthon foundation; Paulsson Trust; G. Nilsson foundation

Available from: 2016-06-01 Created: 2016-05-30 Last updated: 2017-11-30
Lyth, J., Carstensen, J., Synnerstad, I. & Lindholm, C. (2016). Stage-specific direct healthcare costs in patients with cutaneous malignant melanoma. Journal of the European Academy of Dermatology and Venereology, 30(5), 789-793
Open this publication in new window or tab >>Stage-specific direct healthcare costs in patients with cutaneous malignant melanoma
2016 (English)In: Journal of the European Academy of Dermatology and Venereology, ISSN 0926-9959, E-ISSN 1468-3083, Vol. 30, no 5, p. 789-793Article in journal (Refereed) Published
Abstract [en]

Background Clinical stage at diagnosis is a strong prognostic factor for death in cutaneous malignant melanoma (CMM), with worse prognosis at higher stages. However, few studies have investigated how direct healthcare cost per patient varies with clinical stage.

Objective The aim of this study was to determine the stage-specific direct healthcare costs for CMM patients compared to the healthcare costs in the general population in the County of Östergötland, Sweden.

Methods CMM patients in the County of Östergötland diagnosed 2005-2012 were identified from the Swedish cancer registry. Information on clinical stage was collected from the Swedish Melanoma Register (SMR) and cost data from the Cost per Patient database (CPP) for 1 075 CMM patients in Östergötland. CPP contains costs associated with all healthcare contacts per patient including inpatient, outpatient, and primary care. The CMM-related costs were defined as the difference in mean healthcare costs between CMM patients and general population.

Results The first year after CMM diagnosis, the average healthcare costs for CMM patients was 2.8 times higher than in the general population. The healthcare cost ratio varied from 2.0 (stage I) to 10.1 (stage IV) and the CMM-related costs per patient-year varied from €2 670 (stage I) to €29 291 (stage IV). The mean healthcare costs decreased over time but remained significantly higher than in the general population for all clinical stages. During the first year after diagnosis, patients in clinical stage III-IV (7% of CMM patients) accounted for 27% of the total CMM-related healthcare costs.

Conclusions The direct healthcare costs for CMM patients were significantly higher than in the general population independent of clinical stage. CMM patients diagnosed in clinical stage III-IV were associated with particularly high costs and the healthcare system may save resources by finding CMM patients in earlier stages.

National Category
Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:liu:diva-113144 (URN)10.1111/jdv.13110 (DOI)000374554200007 ()
Note

Funding agencies:Regional cancer center South East in Linkoping

Vid tiden för disputation förelåg publikationen som manuskript

Available from: 2015-01-12 Created: 2015-01-12 Last updated: 2017-05-03
Lyth, J. (2015). Clinical-epidemiological studies on cutaneous malignant melanoma: A register approach. (Doctoral dissertation). Linköping: Linköping University Electronic Press
Open this publication in new window or tab >>Clinical-epidemiological studies on cutaneous malignant melanoma: A register approach
2015 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The incidence of cutaneous malignant melanoma (CMM) is steadily increasing. Most of the patients have thin CMM with a good prognosis and a 5-year survival of about 90%. The prognosis is highly related to tumour thickness and clinical stage at diagnosis. Effective systemic treatment for patients with metastatic disease has only recently been available. This thesis aims to increase knowledge of trends in tumour thickness, prognostic factors, socioeconomic differences and medical costs in patients with CMM.

The population-based Swedish melanoma register is the main source of data in all papers in the thesis. Papers I-III include patients from all of Sweden while paper IV is delimited to the County of Östergötland. Cox regression and logistic regression are the main multivariable methods used. Paper IV is focused on stage-specific costs of CMM by comparing direct healthcare costs to a general population.

For men, there has been a shift over time towards thinner tumours at diagnosis accompanied by an improved survival. Women are still diagnosed with considerably thinner tumours and they experience a better survival than men. Tumour ulceration, tumour thickness and Clark’s level of invasion all showed significant independent long-term prognostic information in T1 CMMs. By combining these factors, three distinct prognostic subgroups were identified. Lower level of education was associated with reduced CMM-specific survival, which may at least partially be attributed to a more advanced stage at diagnosis. The direct healthcare costs for CMM patients were significantly higher than for the general population, independent of clinical stage. CMM patients diagnosed in clinical stage III-IV were associated with particularly high costs.

Even though the survival among Swedish patients with CMM is among the highest in the world and still seems to improve, the results of this thesis emphasise the need of improved early detection strategies. This may be of particular concern in men, older women, and groups with a low level of education. The results also imply that the costs for the management of CMM patients may be reduced if early detection efforts are successful and lead to a more favourable stage distribution. The finding of a better risk stratification of thin CMMs may help to improve the management of this large patient group.

Place, publisher, year, edition, pages
Linköping: Linköping University Electronic Press, 2015. p. 51
Series
Linköping University Medical Dissertations, ISSN 0345-0082 ; 1428
Keywords
Melanoma, early detection, population-based, registers, time trends, survival, prognostic factors, tumour thickness, stage at diagnosis, level of education, socioeconomic status, healthcare costs
National Category
Dermatology and Venereal Diseases Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:liu:diva-113145 (URN)10.3384/diss.diva-113145 (DOI)978-91-7519-191-1 (ISBN)
Public defence
2015-02-13, Eken, ingång 65, Campus US, Linköpings Universitet, Linköping, 09:00 (Swedish)
Opponent
Supervisors
Available from: 2015-01-28 Created: 2015-01-12 Last updated: 2016-04-01Bibliographically approved
Krynitz, B., Lundh Rozell, B., Lyth, J., Smedby, K. E. & Lindelof, B. (2015). Cutaneous malignant melanoma in the Swedish organ transplantation cohort: A study of clinicopathological characteristics and mortality. The Journal of American Academy of Dermatology, 73(1), 106-U190
Open this publication in new window or tab >>Cutaneous malignant melanoma in the Swedish organ transplantation cohort: A study of clinicopathological characteristics and mortality
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2015 (English)In: The Journal of American Academy of Dermatology, ISSN 0190-9622, E-ISSN 1097-6787, Vol. 73, no 1, p. 106-U190Article in journal (Refereed) Published
Abstract [en]

Background: Risk of cutaneous melanoma is increased among organ transplant recipients (OTRs) but outcome has rarely been evaluated. Objective: We sought to assess melanoma characteristics and prognosis among OTRs versus the general population. Methods: Using Swedish health care registers, we identified melanomas in OTRs (n = 49) and in the general population (n = 22,496), given a diagnosis between 1984 and 2008 and followed up through December 31, 2012. Tumor slides of posttransplantation melanomas were reviewed. Odds ratios for comparison of histopathological characteristics and hazard ratios of melanoma-specific death were calculated. Results: Among OTRs the trunk was the most common anatomic melanoma site (50% among female vs 51% among male) and 73% (n = 36) of all melanomas were histologically associated with a melanocytic nevus, 63% (n = 31) atypical/dysplastic. Compared with population melanomas, posttransplantation melanomas were more advanced at diagnosis (Clark level III-V: odds ratio 2.2 [95% confidence interval 1.01-4.7, P = .03], clinical stages III-IV: odds ratio 4.2 [1.6-10.8, P = .003]). Risk of melanoma-specific death was increased among OTRs: adjusted hazard ratio 3.0 (1.7-5.3, P = .0002). Limitations: Only posttransplantation melanoma slides were reviewed. Conclusions: Melanomas were more advanced at diagnosis and melanoma-specific survival was poorer in OTRs than in the general population. Prophylactic excision of truncal nevi among OTRs may be advised.

Place, publisher, year, edition, pages
Elsevier, 2015
Keywords
histopathology; immunosuppression; melanocytic nevi; melanoma; melanoma-specific mortality; population-based study; posttransplantation; Swedish Melanoma Register
National Category
Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-120038 (URN)10.1016/j.jaad.2015.03.045 (DOI)000356314100031 ()25929720 (PubMedID)
Note

Funding Agencies|Welander Foundation; Westerberg Foundation; Strategic Research Program in Epidemiology at Karolinska Institutet, Stockholm, Sweden

Available from: 2015-07-06 Created: 2015-07-06 Last updated: 2017-12-04
Lyth, J., Eriksson, H., Hansson, J., Ingvar, C., Jansson, M., Lapins, J., . . . Lindholm, C. (2015). Trends in cutaneous malignant melanoma in Sweden 1997-2011: Thinner tumours and improved survival among men. British Journal of Dermatology, 172(3), 700-706
Open this publication in new window or tab >>Trends in cutaneous malignant melanoma in Sweden 1997-2011: Thinner tumours and improved survival among men
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2015 (English)In: British Journal of Dermatology, ISSN 0007-0963, E-ISSN 1365-2133, Vol. 172, no 3, p. 700-706Article in journal (Refereed) Published
Abstract [en]

Background: Both patient survival and the proportion of patients diagnosed with thin cutaneous malignant melanoma (CMM) have been steadily rising in Sweden as in most western countries, though the rate of improvement in survival appears to have declined in Sweden at the end of last millennium.

Objectives: To analyse the most recent trends in the distribution of tumour thickness (T-category) as well as CMM-specific survival in Swedish patients diagnosed 1997-2011.

Methods: This nationwide population-based study included 30 590 patients registered in the Swedish Melanoma Register (SMR) and diagnosed with a first primary invasive CMM 1997-2011. The patients were followed through 2012 in the national Cause-of-Death Register.

Results: Logistic and Cox regression analyses adjusting for age at diagnosis, tumour site, and health care region were carried out. The odds ratio for being diagnosed with thicker tumours was significantly reduced (P = 0·0008) and the CMM-specific survival significantly improved in men diagnosed 2007-2011 compared to men diagnosed 1997-2001 (hazard ratio=0·81; 95% CI 0·72-0·91, P = 0·0009) while the corresponding differences for women were not significant. Women were diagnosed with significantly thicker tumours during 2002-2006 and a tendency towards decreased survival was observed compared to those diagnosed earlier 1997-2001 and later 2007-2011.

Conclusion: In Sweden, the CMMs of men are detected earlier over time and this seems to be followed by an improved CMM-specific survival for men. Women are still diagnosed with considerably thinner tumours and they experience a better survival than men.

Place, publisher, year, edition, pages
Wiley-Blackwell, 2015
Keywords
malignant melanoma, time trend, survival, tumour thickness, population based
National Category
Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:liu:diva-113143 (URN)10.1111/bjd.13483 (DOI)000351400500029 ()25323770 (PubMedID)
Available from: 2015-01-12 Created: 2015-01-12 Last updated: 2017-12-05Bibliographically approved
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