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Druvefors, Pelle
Publications (3 of 3) Show all publications
Myrelid, P., Druvefors, P. & Andersson, P. (2014). Recurrent volvulus of an ileal pouch requiring repeat pouchopexy: a lesson learnt.. Case Reports in Surgery, 2014, 807640
Open this publication in new window or tab >>Recurrent volvulus of an ileal pouch requiring repeat pouchopexy: a lesson learnt.
2014 (English)In: Case Reports in Surgery, ISSN 2090-6919, E-ISSN 2090-6900, Vol. 2014, p. 807640-Article in journal (Refereed) Published
Abstract [en]

Introduction. Restorative surgery for ulcerative colitis with ileal pouch anal anastomosis (IPAA) is frequently accompanied by complications. Volvulus of the ileal pouch is one of the most rarely reported late complications and to our knowledge no report exists on reoperative surgery for this condition. Case Report. A 58-year-old woman who previously had undergone restorative proctocolectomy due to ulcerative colitis with an IPAA presented with volvulus of the pouch. She was operated with a single row pouchopexy to the presacral fascia. Two months later she returned with a recurrent volvulus. At reoperation, the pouch was found to have become completely detached from the fascia. A new pexy was made by firmly anchoring the pouch with two rows of sutures to the presacral fascia as well as with sutures to the lateral pelvic walls. At follow-up after five months she was free of symptoms. Conclusion. This first report ever on reoperative surgery for volvulus of a pelvic pouch indicates that a single row pouchopexy might be insufficient for preventing retwisting. Several rows seem to be needed.

Place, publisher, year, edition, pages
Hindawi Publishing Corporation, 2014
National Category
Other Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-115299 (URN)10.1155/2014/807640 (DOI)25110603 (PubMedID)
Available from: 2015-03-12 Created: 2015-03-12 Last updated: 2017-12-04Bibliographically approved
Escobar Kvitting, J.-P., Andersson, P. & Druvefors, P. (2009). A phytobezoar in the acute abdomen. American Journal of Surgery, 197(2), e21-e22
Open this publication in new window or tab >>A phytobezoar in the acute abdomen
2009 (English)In: American Journal of Surgery, ISSN 0002-9610, E-ISSN 1879-1883, Vol. 197, no 2, p. e21-e22Article in journal (Refereed) Published
Abstract [en]

A phytobezoar is a rare differential diagnosis in the acute abdomen. An 89-year-old woman presented with lower abdominal pain. A computed tomography scan and ultrasound suggested the presence of a bezoar. A phytobezoar was extracted surgically, and a resection was performed of the perforated small bowel segment. The etiology and management of phytobezoars are discussed.

Place, publisher, year, edition, pages
Elsevier, 2009
Keywords
Phytobezoar; Small intestinal perforation
National Category
Surgery
Identifiers
urn:nbn:se:liu:diva-18744 (URN)10.1016/j.amjsurg.2008.02.013 (DOI)18789409 (PubMedID)
Available from: 2009-06-03 Created: 2009-06-03 Last updated: 2017-12-13Bibliographically approved
Clinchy, B., Fransson, A., Druvefors, P., Hellsten, A., Håkansson, A., Gustafsson, B., . . . Håkansson, L. (2007). Preoperative interleukin-6 production by mononuclear blood cells predicts survival after radical surgery for colorectal carcinoma. Cancer, 109(9), 1742-1749
Open this publication in new window or tab >>Preoperative interleukin-6 production by mononuclear blood cells predicts survival after radical surgery for colorectal carcinoma
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2007 (English)In: Cancer, ISSN 0008-543X, E-ISSN 1097-0142, Vol. 109, no 9, p. 1742-1749Article in journal (Refereed) Published
Abstract [en]

BACKGROUND. Colorectal cancer is one of the most common forms of cancer in the Western world. Staging based on histopathology is currently the most accurate predictor of outcome after surgery. Colorectal cancer is curable if treated at an early stage (stage I-III). However, for tumors in stages II and III there is a great need for tests giving more accurate prognostic information defining the patient population in need of closer follow-up and/or adjuvant therapy. Furthermore, tests that provide prognostic information preoperatively could provide a guide both for preoperative oncologic treatment and the surgical procedure. METHODS. Peripheral blood mononuclear cells (PBMCs) were isolated preoperatively, within a week before primary surgery, from 39 patients undergoing surgery for colorectal cancer. The PBMCs were cultured in vitro for 24 hours in the presence of autologous serum and lipopolysaccharide (LPS). Interleukin-6 (IL-6) production was measured with enzyme-linked immunosorbent assay (ELISA). Staging based on histopathology was performed in all patients. Patients were followed for at least 54 months. RESULTS. A production of >5000 pg/mL of IL-6 identified colorectal cancer patients with a poor prognosis. Eight out of 13 patients with >5000 pg/mL IL-6 died from cancer within the follow-up period, whereas no cancer-related deaths were recorded among 21 patients with 5000 pg/mL IL-6 or less. A multivariate Cox regression analysis, stratified for T- and N-stage, identified IL-6 production as an independent prognostic factor. CONCLUSIONS. IL-6 production in vitro by PBMC can predict survival after radical surgery for colorectal cancer. © 2007 American Cancer Society.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-39824 (URN)10.1002/cncr.22623 (DOI)51413 (Local ID)51413 (Archive number)51413 (OAI)
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2017-12-13
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