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Friberg, Örjan
Publications (10 of 18) Show all publications
Tajik, B., Vidlund, M., Sundbom, P., Friberg, Ö., Holm, J., Vanky, F. & Svedjeholm, R. (2014). Intravenous glutamatereduces the need for inotropes in patients with heart failure after CABG foracute coronary syndrome?. In: : . Paper presented at 29th Annual meeting of the European Association of Cardiothoracic Anesthesiologists, Florence, Italy.
Open this publication in new window or tab >>Intravenous glutamatereduces the need for inotropes in patients with heart failure after CABG foracute coronary syndrome?
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2014 (English)Conference paper, Poster (with or without abstract) (Other academic)
National Category
Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-114367 (URN)
Conference
29th Annual meeting of the European Association of Cardiothoracic Anesthesiologists, Florence, Italy
Available from: 2015-02-19 Created: 2015-02-19 Last updated: 2015-11-09
Svedjeholm, R., Tajik, B., Vidlund, M., Friberg, Ö., Holm, J., Vanky, F. & Håkansson, E. (2014). Intravenous glutamatereduces the need for inotropes in patients with heart failure after CABG foracute coronary syndrome?. In: : . Paper presented at 6th Joint Scandinavian conference in Cardiothoracic Surgery, Gothenburg, Sweden.
Open this publication in new window or tab >>Intravenous glutamatereduces the need for inotropes in patients with heart failure after CABG foracute coronary syndrome?
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2014 (English)Conference paper, Poster (with or without abstract) (Other academic)
National Category
Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-114365 (URN)
Conference
6th Joint Scandinavian conference in Cardiothoracic Surgery, Gothenburg, Sweden
Available from: 2015-02-19 Created: 2015-02-19 Last updated: 2015-03-31
Holm, J., Vidlund, M., Vanky, F., Friberg, Ö., Håkanson, E. & Svedjeholm, R. (2013). Does preoperative NT-proBNP provide additional prognostic information to EuroSCORE II in patients undfergoing CABG?. In: : . Paper presented at 28th Annual meeting of the European Association of Cardiothoracic Anesthesiologists, Barcelona, Spain, June 6-8, 2013.
Open this publication in new window or tab >>Does preoperative NT-proBNP provide additional prognostic information to EuroSCORE II in patients undfergoing CABG?
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2013 (English)Conference paper, Poster (with or without abstract) (Other academic)
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-103348 (URN)
Conference
28th Annual meeting of the European Association of Cardiothoracic Anesthesiologists, Barcelona, Spain, June 6-8, 2013
Available from: 2014-01-17 Created: 2014-01-17 Last updated: 2014-02-04
Holm, J., Vidlund, M., Vanky, F., Friberg, Ö., Håkansson, E., Walther, S. & Svedjeholm, R. (2013). NT-proBNP provides additional prognostic information to Euroscoe II in patients undergoing CABG. In: : . Paper presented at Thoraxmöte, 16-18 oktober 2013, Linköping.
Open this publication in new window or tab >>NT-proBNP provides additional prognostic information to Euroscoe II in patients undergoing CABG
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2013 (Swedish)Conference paper, Oral presentation with published abstract (Other academic)
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-100827 (URN)
Conference
Thoraxmöte, 16-18 oktober 2013, Linköping
Available from: 2013-11-13 Created: 2013-11-13 Last updated: 2015-05-04
Svedjeholm, R., Vidlund, M., Håkanson, E., Friberg, Ö., Juhl-Andersen, S., Holm, J., . . . Sharma, R. (2011). GLUTAMICS: A RANDOMIZED CLINICAL TRIAL ON GLUTAMATE INFUSION IN PATIENTS OPERATED FOR ACUTE CORONARY SYNDROME in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol 57, issue 14, pp E938-E938. In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (pp. E938-E938). Elsevier Science, 57(14)
Open this publication in new window or tab >>GLUTAMICS: A RANDOMIZED CLINICAL TRIAL ON GLUTAMATE INFUSION IN PATIENTS OPERATED FOR ACUTE CORONARY SYNDROME in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol 57, issue 14, pp E938-E938
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2011 (English)In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Elsevier Science , 2011, Vol. 57, no 14, p. E938-E938Conference paper, Published paper (Refereed)
Abstract [en]

n/a

Place, publisher, year, edition, pages
Elsevier Science, 2011
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-69919 (URN)000291695100939 ()
Available from: 2011-08-09 Created: 2011-08-08 Last updated: 2011-08-19
Friberg, Ö. & Svedjeholm, R. (2008). Letter: Post-sternotomy percutaneous tracheostomy and risky multivariable analyses [Letter to the editor]. European Journal of Cardio-Thoracic Surgery, 34(4), 930-931
Open this publication in new window or tab >>Letter: Post-sternotomy percutaneous tracheostomy and risky multivariable analyses
2008 (English)In: European Journal of Cardio-Thoracic Surgery, ISSN 1010-7940, E-ISSN 1873-734X, Vol. 34, no 4, p. 930-931Article in journal, Letter (Other academic) Published
Abstract [en]

  

Place, publisher, year, edition, pages
Oxford University Press, 2008
Keywords
cardiac surgery, postoperative complication, sternal wound infection, risk factors, tracheostomy, logistic regression analysis
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-44758 (URN)10.1016/j.ejcts.2008.07.022 (DOI)77542 (Local ID)77542 (Archive number)77542 (OAI)
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2017-12-13Bibliographically approved
Vidlund, M., Holm, J., Håkansson, E., Friberg, Ö., Sunnermalm, L., Vánky, F. & Svedjeholm, R. (2008). The S100-B substudy of the Glutamics-trial: Elevation of S-100B is linked to aortic calcification and postoperative confusion.. In: 57th Annual meeting of the Scandinavian Association for Thoracic Surgery,2008.
Open this publication in new window or tab >>The S100-B substudy of the Glutamics-trial: Elevation of S-100B is linked to aortic calcification and postoperative confusion.
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2008 (English)In: 57th Annual meeting of the Scandinavian Association for Thoracic Surgery,2008, 2008Conference paper, Published paper (Refereed)
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-44750 (URN)77528 (Local ID)77528 (Archive number)77528 (OAI)
Available from: 2009-10-10 Created: 2009-10-10
Friberg, Ö., Svedjeholm, R., Källman, J. & Söderquist, B. (2007). Incidence, microbiological findings and clinical presentation of sternal wound infections after cardiac surgery with and without local gentamicin prophylaxis. European Journal of Clinical Microbiology and Infectious Diseases, 26(2), 91-97
Open this publication in new window or tab >>Incidence, microbiological findings and clinical presentation of sternal wound infections after cardiac surgery with and without local gentamicin prophylaxis
2007 (English)In: European Journal of Clinical Microbiology and Infectious Diseases, ISSN 0934-9723, E-ISSN 1435-4373, Vol. 26, no 2, p. 91-97Article in journal (Refereed) Published
Abstract [en]

Sternal wound infection (SWI) is a serious complication after cardiac surgery. In a previous randomized controlled trial, the addition of local collagen-gentamicin in the sternal wound before wound closure was found to significantly reduce the incidence of postoperative wound infections compared with the routine intravenous prophylaxis of isoxazolyl-penicillin only. The aims of the present study were to analyse the microbiological findings of the SWIs from the previous trial as well as to correlate these findings with the clinical presentation of SWI. Differences in clinical presentation of SWIs, depending on the causative agent, could be identified. Most infections had a late, insidious onset, and the majority of these were caused by staphylococci, predominantly coagulase-negative staphylococci. The clinically most fulminant infections were caused by gram-negative bacteria and presented early after surgery. Local administration of gentamicin reduced the incidence of SWIs caused by all major, clinically important bacterial species. Propionibacterium acnes was identified as a possible cause of SWI and may be linked to instability in the sternal fixation. There was no indication of an increase in the occurrence of gentamicin-resistant bacterial isolates in the treatment group. Furthermore, the addition of local collagen-gentamicin reduced the incidence of SWIs caused by methicillin-resistant coagulase-negative staphylococci. This technique warrants further evaluation as an alternative to prophylactic vancomycin in settings with a high prevalence of methicillin-resistant Staphylococcus aureus.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-13927 (URN)10.1007/s10096-006-0252-6 (DOI)
Available from: 2006-07-20 Created: 2006-07-20 Last updated: 2017-12-13
Friberg, Ö., Dahlin, L.-G., Levin, L.-Å., Magnusson, A., Granfeldt, H., Källman, J. & Svedjeholm, R. (2006). Cost effectiveness of local collagen-gentamicin as prophylaxis for sternal wound infections in different risk groups. Scandinavian Cardiovascular Journal, 40(2), 117-125
Open this publication in new window or tab >>Cost effectiveness of local collagen-gentamicin as prophylaxis for sternal wound infections in different risk groups
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2006 (English)In: Scandinavian Cardiovascular Journal, ISSN 1401-7431, Vol. 40, no 2, p. 117-125Article in journal (Refereed) Published
Abstract [en]

Objectives. In a randomized trial addition of local collagen-gentamicin in the sternal wound reduced the rate of sternal wound infection (SWI) to about 50% compared to intravenous prophylaxis alone. The aim of the present study was to evaluate the economic rationale for its use in every-day clinical practice. This includes the question whether high-risk groups that may have particular benefit should be identified.

Design. For each patient with SWI in the trial the costs attributable to the SWI were calculated. Risk factors for SWI were identified and any heterogeneity of the effect of the prophylaxis examined.

Results. The mean cost of a SWI was about 14500 Euros. A cost effectiveness analysis showed that the prophylaxis was cost saving. The positive net balance was even higher in risk groups. Assignment to the control group, overweight, diabetes, younger age, mammarian artery use, left ventricular ejection fraction < 35% and longer operation time were independent risk factors for infection.

Conclusion. The addition of local collagen-gentamicin to intravenous antibiotic prophylaxis was dominant, i.e. resulted in both lower costs and fewer wound infections.

Keywords
Cardiac Surgery; Cardiology
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-13926 (URN)10.1080/14017430500363024 (DOI)
Available from: 2006-07-20 Created: 2006-07-20
Friberg, Ö., Dahlin, L.-G., Söderquist, B., Källman, J. & Svedjeholm, R. (2006). Influence of more than six sternal fixation wires on the incidence of deep sternal wound infection. The thoracic and cardiovascular surgeon, 54(7), 468-473
Open this publication in new window or tab >>Influence of more than six sternal fixation wires on the incidence of deep sternal wound infection
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2006 (English)In: The thoracic and cardiovascular surgeon, ISSN 0171-6425, E-ISSN 1439-1902, Vol. 54, no 7, p. 468-473Article in journal (Refereed) Published
Abstract [en]

Background: The aim of the present study was to examine the influence of the number of sternal fixation wires used on deep sternal wound infection rate and to analyze any possible interaction between this and local collagen-gentamicin prophylaxis evaluated in a previous trial. Methods: The number of sternal fixation wires in all patients from one of two participating centers was counted. The patients were categorized according to six or fewer (standard technique, ST group) vs. seven or more wires (extra wires, XW group). Results: The incidence of deep sternal wound infection was 4.2% in the ST group and 0.4% in the XW group (p = 0.001). An analysis of the effect of local gentamicin, excluding the ST group from the analysis, showed an approximately 70% reduction in sternal wound infection for all depths. Conclusion: This study supports the theory that additional fixation wires at the lower sternum actually reduce the incidence of deep wound infections. We suggest that a rigid sternal fixation is required to achieve the full benefit of local collagen-gentamicin prophylaxis. © Georg Thieme Verlag KG.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-36805 (URN)10.1055/s-2006-924437 (DOI)32646 (Local ID)32646 (Archive number)32646 (OAI)
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2017-12-13
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