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Nyström Kronander, Ulla
Publications (9 of 9) Show all publications
Nyström, U. & Ahlbeck, L. (2018). Allergi och annan överkänslighet (6ed.). In: Ulf Dahlström, Stergios Kechagias, Leif Stenke (Ed.), Internmedicin: (pp. 31-58). Stockholm: Liber
Open this publication in new window or tab >>Allergi och annan överkänslighet
2018 (English)In: Internmedicin / [ed] Ulf Dahlström, Stergios Kechagias, Leif Stenke, Stockholm: Liber, 2018, 6, p. 31-58Chapter in book (Other academic)
Place, publisher, year, edition, pages
Stockholm: Liber, 2018 Edition: 6
National Category
Respiratory Medicine and Allergy
Identifiers
urn:nbn:se:liu:diva-154642 (URN)9789147113262 (ISBN)
Available from: 2019-02-24 Created: 2019-02-24 Last updated: 2020-01-17Bibliographically approved
Nyström Kronander, U. & Ahlbeck, L. (2018). Atopi, allergi och överkänslighet. In: Läkemedelsboken: . Läkemedelsverket
Open this publication in new window or tab >>Atopi, allergi och överkänslighet
2018 (Swedish)In: Läkemedelsboken, Läkemedelsverket , 2018Chapter in book (Other academic)
Place, publisher, year, edition, pages
Läkemedelsverket, 2018
Series
Läkemedelsboken, ISSN 0347-8343
National Category
Respiratory Medicine and Allergy
Identifiers
urn:nbn:se:liu:diva-154641 (URN)
Available from: 2019-02-24 Created: 2019-02-24 Last updated: 2019-03-08
Ahlbeck, L., Ahlberg, E., Nyström Kronander, U., Björkander, J. & Jenmalm, M. (2018). Intralymphatic allergen immunotherapy against pollen allergy. A 3-year open follow-up study of 10 patients. Annals of Allergy, Asthma & Immunology, 121(5), 626-627
Open this publication in new window or tab >>Intralymphatic allergen immunotherapy against pollen allergy. A 3-year open follow-up study of 10 patients
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2018 (English)In: Annals of Allergy, Asthma & Immunology, ISSN 1081-1206, E-ISSN 1534-4436, Vol. 121, no 5, p. 626-627Article in journal (Refereed) Published
Abstract [en]

To date, allergen immunotherapy (AIT) is the only treatment that affects the long-term development of allergic rhinoconjunctivitis and induces clinical tolerance primarily by stimulating regulatory T (Treg) cells, attenuating T helper 2 (Th2) responses and synthesis of blocking antibodies1. Conventional AIT with subcutaneous injections, sublingual tablets or drops is effective, but consumes time and resources 2.

Place, publisher, year, edition, pages
Elsevier, 2018
Keywords
Immunotherapy, Intralymphatic, Allergy, Rhinoconjunctivitis, T-cells
National Category
Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-150594 (URN)10.1016/j.anai.2018.07.010 (DOI)000448665400022 ()30021119 (PubMedID)
Note

Funding agencies: Region Ostergotland; Allergy Center in Linkoping; Medical Research Council of Southeast Sweden (FORSS); Bergh Foundation; Asthma and Allergy Association of Sweden

Available from: 2018-08-28 Created: 2018-08-28 Last updated: 2019-04-09Bibliographically approved
Bergfors, E., Hermansson, G., Nyström Kronander, U., Falk, L., Valter, L. & Trollfors, B. (2014). How common are long-lasting, intensely itching vaccination granulomas and contact allergy to aluminium induced by currently used pediatric vaccines? A prospective cohort study. European Journal of Pediatrics, 173(10), 1297-1307
Open this publication in new window or tab >>How common are long-lasting, intensely itching vaccination granulomas and contact allergy to aluminium induced by currently used pediatric vaccines? A prospective cohort study
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2014 (English)In: European Journal of Pediatrics, ISSN 0340-6199, E-ISSN 1432-1076, Vol. 173, no 10, p. 1297-1307Article in journal (Refereed) Published
Abstract [en]

The frequency of long-lasting, intensely itching subcutaneous nodules at the injection site for aluminium (Al)-adsorbed vaccines (vaccination granulomas) was investigated in a prospective cohort study comprising 4,758 children who received either a diphtheria-tetanus-pertussis-polio-Haemophilus influenzae type b vaccine (Infanrix®, Pentavac®) alone or concomitant with a pneumococcal conjugate (Prevenar). Both vaccines were adsorbed to an Al adjuvant. Altogether 38 children (0.83 %) with itching granulomas were identified, epicutaneously tested for Al sensitisation and followed yearly. Contact allergy to Al was verified in 85 %. The median duration of symptoms was 22 months in those hitherto recovered. The frequency of granulomas induced by Infanrix® was >0.66 % and by Prevenar >0.35 %. The risk for granulomas increased from 0.63 to 1.18 % when a second Al-adsorbed vaccine was added to the schedule. Conclusion: Long-lasting itching vaccination granulomas are poorly understood but more frequent than previously known after infant vaccination with commonly used diphtheria-tetanus-pertussis-polio-Haemophilus influenzae type b and pneumococcal conjugate vaccines. The risk increases with the number of vaccines given. Most children with itching granulomas become contact allergic to aluminium. Itching vaccination granulomas are benign but may be troublesome and should be recognised early in primary health care to avoid unnecessary investigations, anxiety and mistrust.

Place, publisher, year, edition, pages
Springer Berlin/Heidelberg, 2014
Keywords
Itching nodule, Granuloma, Contact allergy, Aluminium, Adsorbed vaccines, Child health care
National Category
Pediatrics
Identifiers
urn:nbn:se:liu:diva-107372 (URN)10.1007/s00431-014-2318-2 (DOI)000342227700004 ()24752308 (PubMedID)
Available from: 2014-06-11 Created: 2014-06-11 Last updated: 2017-12-05
Bergfors, E., Lundmark, K. & Nyström Kronander, U. (2013). A child with a long-standing, intensely itching subcutaneous nodule on a thigh: an uncommon (?) reaction to commonly used vaccines. BMJ Case Reports
Open this publication in new window or tab >>A child with a long-standing, intensely itching subcutaneous nodule on a thigh: an uncommon (?) reaction to commonly used vaccines
2013 (English)In: BMJ Case Reports, ISSN 1757-790XArticle in journal (Refereed) Published
Abstract [en]

A 2-year-old girl presented with an intensely itching subcutaneous nodule on the front of a thigh. The nodule persisted for 10 months until it was excised. Subsequent investigation for malignancy and systemic disease showed no pathological findings. The diagnosis, persistent itching vaccination granuloma, was revealed by hazard almost 2 years after the onset of symptoms. Persistent itching subcutaneous nodules at the injection site for aluminium containing vaccines (mostly diphtheria-tetanus-pertussis combination vaccines for primary immunisation of infants) may appear with a long delay after the vaccination (months), cause prolonged itching (years) and are often associated with contact allergy to aluminium. The condition is poorly recognised in Health Care which may lead to prolonged symptoms and unnecessary investigations.

Place, publisher, year, edition, pages
BMJ Publishing Group, 2013
Keywords
itching, subcutaneous, nodule, vaccine
National Category
Pediatrics Dermatology and Venereal Diseases General Practice
Identifiers
urn:nbn:se:liu:diva-91041 (URN)10.1136/bcr-2012-007779 (DOI)23354861 (PubMedID)
Available from: 2013-04-12 Created: 2013-04-12 Last updated: 2018-01-11
Nyström Kronander, U. & Nilsson, L. (2009). Äggallergi och vaccin mot nya influensan. Handlingsplan finns i Östergötland. Läkartidningen, 106(48), 3230
Open this publication in new window or tab >>Äggallergi och vaccin mot nya influensan. Handlingsplan finns i Östergötland
2009 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 106, no 48, p. 3230-Article in journal (Refereed) Published
Abstract [sv]

Det har diskuterats om barn och vuxna med äggallergi ska erhålla vaccin mot den nya influen­san. Det finns nämligen spårmängder av äggprotein i vaccinet.

Risken för allergisk reaktion är dock mycket liten, eftersom mängderna är i storleksordningen några nanogram.

Vi har i Östergötland påbörjat en handlingsplan för vaccination av barn och vuxna med äggallergi.

Place, publisher, year, edition, pages
Läkartidningen Förlag AB, 2009
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-86456 (URN)20101832 (PubMedID)
Note

Titel på engelska: Egg allergy and vaccine against the new influenze. A plan of action in Ostergotland

Available from: 2012-12-15 Created: 2012-12-15 Last updated: 2017-12-06
Nyström Kronander, U., Falkenberg, M. & Zetterström, O. (2004). Prevalence and incidence of asthma related to waist circumference and BMI in a Swedish community sample. Respiratory Medicine, 98(11), 1108-1116
Open this publication in new window or tab >>Prevalence and incidence of asthma related to waist circumference and BMI in a Swedish community sample
2004 (English)In: Respiratory Medicine, ISSN 0954-6111, E-ISSN 1532-3064, Vol. 98, no 11, p. 1108-1116Article in journal (Refereed) Published
Abstract [en]

Both asthma and obesity have become more common in affluent societies during the recent decades and several studies have shown a correlation between the presence of asthma and obesity. In order to further study this association we have investigated a population from a community in southern Sweden, where almost all inhabitants had their body indices measured as part of a study on diabetes at a primary care centre. An asthma unit working with a structured care programme for asthma was available. This organisation enabled us to study whether body mass index and waist circumference was associated with having or developing asthma. There was a significant association between both overweight, increased waist circumference and asthma, P

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-23558 (URN)10.1016/j.rmed.2004.03.022 (DOI)3036 (Local ID)3036 (Archive number)3036 (OAI)
Available from: 2009-10-07 Created: 2009-10-07 Last updated: 2017-12-13
Nyström Kronander, U. (2003). Astma och övervikt - hur ser sambandet egentligen ut?. Medikament, 4, 68-73
Open this publication in new window or tab >>Astma och övervikt - hur ser sambandet egentligen ut?
2003 (Swedish)In: Medikament, ISSN 1402-3881, Vol. 4, p. 68-73Article in journal (Other (popular science, discussion, etc.)) Published
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-26639 (URN)11204 (Local ID)11204 (Archive number)11204 (OAI)
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2011-01-13
Ställberg, B., Nyström Kronander, U., Olsson, P., Gottberg, L., Rönmark, E. & Lundbäck, B. (2003). Living with asthma in Sweden - The ALMA study. Respiratory Medicine, 97(7), 835-843
Open this publication in new window or tab >>Living with asthma in Sweden - The ALMA study
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2003 (English)In: Respiratory Medicine, ISSN 0954-6111, E-ISSN 1532-3064, Vol. 97, no 7, p. 835-843Article in journal (Refereed) Published
Abstract [en]

Background: Recently performed studies have found a number of limitations in the daily lives of asthmatics, and a large disparity between the perception of the sufferers and what health care professionals believe matters to asthmatics. Aim: What matters to Swedish asthma patients, what medicines do they use, and are they compliant with given prescriptions? A further aim was to compare perceptions about asthma and asthma management in asthmatics and among Swedish general practitioners (GP). Design: A structured telephone interview of a representative sample of Swedish asthmatics, and a mailed questionnaire survey among GPs from different parts of Sweden. Methods: Screening by telephone of a random sample of 10,350 subjects aged 18-45. Of those, 240 were subsequently selected for a detailed structured telephone interview about their asthma. A mailed structured questionnaire containing similar questions to those asked of the asthmatics was sent to 600 GPs, and 139 returned completed answers. Results: 16% of the asthmatics reported (asthma) symptoms occurring every day during the previous month. Nocturnal symptoms at least twice per week were reported by 19%. Both these were reported by considerably higher proportions of the asthmatics than the GPs had expected. A large majority classified their disease as mild or very mild, although great majority reported frequent symptoms. Activities or situations which caused symptoms of asthma often or "now and then" were physical exertion, 67%, bad weather, 59%, contact with animals/pets, 58%, and visits to cafés or restaurants, 36%, and several asthmatics avoided these activities due to their asthma. Conclusion: A great majority of asthmatics report a large number of symptoms and limitations in their daily living in proportions which were roughly expected by the GPs. © 2003 Elsevier Science Ltd. All rights reserved.

Place, publisher, year, edition, pages
Elsevier, 2003
Keywords
Asthma, Epidemiology, Living restrictions, Medicines, Symptoms
National Category
Respiratory Medicine and Allergy
Identifiers
urn:nbn:se:liu:diva-46577 (URN)10.1016/S0954-6111(03)00040-4 (DOI)000183882000012 ()
Available from: 2009-10-11 Created: 2009-10-11 Last updated: 2017-12-13Bibliographically approved
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