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Hydén, Dag
Publications (10 of 61) Show all publications
Westerberg, J., Harder, H., Magnuson, B., Westerberg, L. & Hydén, D. (2011). Ten-year myringoplasty series: does the cause of perforation affect the success rate?. JOURNAL OF LARYNGOLOGY AND OTOLOGY, 125(2), 126-132
Open this publication in new window or tab >>Ten-year myringoplasty series: does the cause of perforation affect the success rate?
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2011 (English)In: JOURNAL OF LARYNGOLOGY AND OTOLOGY, ISSN 0022-2151, Vol. 125, no 2, p. 126-132Article in journal (Refereed) Published
Abstract [en]

Objective: To present the results of primary myringoplasty procedures together with the perforation cause, perforation size and site, surgeons experience, and surgical method, and to investigate how these factors relate to graft take rates. Study design: Retrospective chart review of 243 consecutive patients undergoing primary myringoplasty with temporalis fascia underlay over a 10-year period from 1994 to 2004. Results: The overall graft take rate was 95 per cent. The retroauricular approach resulted in a 97 per cent graft take rate, whereas a significantly lower rate (77 per cent) was seen for surgery conducted via the endaural approach, or via an ear speculum. There was no relationship between other factors and tympanic membrane healing. Conclusion: No association was found between perforation cause and graft take rate. The underlay technique is safe and reliable, and the retroauricular approach is preferable as it enables good surgical access and has better results.

Place, publisher, year, edition, pages
Cambridge University Press, 2011
Keywords
Tympanic Membrane Perforation, Myringoplasty, Otologic Surgical Procedures, Outcomes Assessment
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-67016 (URN)10.1017/S0022215110002069 (DOI)000287656300004 ()
Available from: 2011-03-25 Created: 2011-03-25 Last updated: 2012-03-23
Hydén, D. & Arlinger, S. (2009). On light-induced sneezing. EYE, 23(11), 2112-2114
Open this publication in new window or tab >>On light-induced sneezing
2009 (English)In: EYE, ISSN 0950-222X, Vol. 23, no 11, p. 2112-2114Article in journal (Refereed) Published
Abstract [en]

Purpose To investigate whether the tickling inside the nose before a light-induced sneeze in susceptible individuals is correlated to a recordable local activity or not. Methods Seven healthy volunteers, three with a history of light-induced sneezing, were stimulated with stroboscopic light or a strong halogen lamp. Recording was done with an evoked potential averaging technique via intranasal electrodes placed in such a way that they substantially reduced the strong electrical response from the retina. Results Despite an adequate light stimulus, no reproducible electrical activity could be recorded from any of the members in any experiment. Conclusion Light-induced sneezing is presumably a central phenomenon. The electrical activity travels through the optic pathways straight to the trigeminal nucleus and the tickling is a referred sensation. A genetic variation in the distance between the optic pathways (colliculus superior) and the mesencephalic part of the trigeminal nucleus may explain why light-induced sneezing is more common in certain families and races.

Keywords
light-induced sneezing (ACHOO-reflex), evoked potential averaging technique, central reflex, genetic variation
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-52378 (URN)10.1038/eye.2009.165 (DOI)
Available from: 2009-12-18 Created: 2009-12-18 Last updated: 2009-12-18
Hydén, D. & Arlinger, S. (2007). On the sneeze-reflex and its control. Rhinology, 45(3), 218-219
Open this publication in new window or tab >>On the sneeze-reflex and its control
2007 (English)In: Rhinology, ISSN 0300-0729, E-ISSN 1996-8604, Vol. 45, no 3, p. 218-219Article in journal (Refereed) Published
Abstract [en]

Experiments in cats have shown that sneezing can be induced using low intensity electrical current. This study focusses on answering the question whether the sneezing-reflex can also be induced in man through electrical stimulation, whether it is reproducible, and if the response can be abolished pharmacologically? Three healthy males were tested using intranasal stimulation in different parts of the nose using a current from an electric pulse generator. Using currents in the range 2-11 mA, it was possible to induce and reproduce sneezing in the anterior portion of the nose corresponding to the distribution area of the anterior ethmoidal nerve. In one tested subject, local anaesthetics applied to the mucous membranes of the nose abolished the sneezing. Sneeze reflex-reduction may be one way to reduce viral contamination between subjects. Further research could include pharmacological investigations to identify a sneeze-inhibiting substance with small risks for side effects that can be added to common cold nasal sprays.

Keywords
electrically-induced sneezing, pharmacological sneezing-control
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-39730 (URN)50933 (Local ID)50933 (Archive number)50933 (OAI)
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2017-12-13
Hydén, D., Åkerlind, B. & Peebo, M. (2006). Inner ear and facial nerve complications of acute otitis media with focus on bacteriology and virology. Acta Oto-Laryngologica, 126(5), 460-466
Open this publication in new window or tab >>Inner ear and facial nerve complications of acute otitis media with focus on bacteriology and virology
2006 (English)In: Acta Oto-Laryngologica, ISSN 0001-6489, E-ISSN 1651-2251, Vol. 126, no 5, p. 460-466Article in journal (Refereed) Published
Abstract [en]

Conclusion. Among 20 patients with inner ear complications and/or peripheral facial palsy secondary to acute otitis media (AOM) a proven or probable bacteriological cause was found in 13 (65%). In seven patients (35%), a proven or probable viral cause was found. Only two of the patients (10%), with a proven bacterial AOM and a clinical picture of a purulent labyrinthitis in both, together with a facial palsy in one, had a substantial degree of dysfunction. Although the number of patients in this study is relatively low our findings show that inner ear complications and facial palsy due to AOM can be of both bacterial and viral origin. Severe sequelae were found only where a bacterial origin was proven. Objectives. Inner ear complications and/or peripheral facial palsy secondary to AOM are rare. The general understanding is that they are due to bacterial infections. However, in some of these patients there are no clinical or laboratory signs of bacterial infections and they have negative bacterial cultures. During recent years different viruses have been isolated from the middle ear or serologically proven in AOM patients and are thought to play a pathogenetic role. We suggest that in some cases of AOM complications from the inner ear and the facial nerve can be caused by viruses. The purpose of our study was to analyze infectious agents present in patients with inner ear complications and/or facial palsy arising from AOM. Patients and methods. The medical records of 20 patients who had inner ear complications and/or facial palsy following AOM (unilateral in 18, bilateral in 2) between January 1989 and March 2003 were evaluated. Bacterial cultures were carried out for all patients. Sera from 12 of the patients were stored and tested for a battery of specific viral antibodies. In three patients, investigated between November 2002 and March 2003, viral cultures were also performed on samples from the middle ear and nasopharynx. Results. Nineteen patients had inner ear symptoms. Eight of them had a unilateral sensorineural hearing loss and vertigo, three had vertigo as an isolated symptom and one, with bilateral AOM, had bilateral sensorineural hearing loss. Seven patients had a combination of facial palsy and inner ear symptoms (unilateral sensorineural hearing loss in three, unilateral sensorineural hearing loss and vertigo in two, bilateral sensorineural hearing loss and vertigo in one, with bilateral AOM, and vertigo alone in one). One patient had an isolated facial palsy. Healing was complete in 11 of the 20 patients. In seven patients a minor defect remained at follow-up (a sensorineural hearing loss at higher frequencies in all). Only two patients had obvious defects (a pronounced hearing loss in combination with a moderate to severe facial palsy (House-Brackman grade 4) in one, distinct vestibular symptoms and a total caloric loss in combination with a high-frequency loss in the other. Eight patients had positive bacteriological cultures from middle ear contents: Streptococcus pneumoniae in two, beta-hemolytic Streptococcus group A in two, beta-hemolytic Streptococcus group A together with Staphylococcus aureus in one, Staph. aureus alone in one and coagulase-negative staphylococci (interpreted as pathogens) in two. In the 12 patients with negative cultures, there was a probable bacteriological cause due to the outcome in SR/CRP and leukocyte count in five. In four patients serological testing showed a concomitant viral infection that was interpreted to be the cause (varicella zoster virus in two, herpes simplex virus in one and adenovirus in one.) In three there was a probable viral cause despite negative viral antibody test due to normal outcome in SR/CRP, normal leukocyte count, serous fluid at myringotomy and a relatively short pre-complication antibiotic treatment period. © 2006 Taylor & Francis.

Keywords
Acute otitis medica, inner ear complications, facial palsy, bacteria, viruses
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-35661 (URN)10.1080/00016480500401043 (DOI)28066 (Local ID)28066 (Archive number)28066 (OAI)
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2017-12-13
Hydén, D. (2006). Kirurgisk behandling av livshotande infektioner vardagsarbete för öronläkarna på Key-Åbergs tid. Smittnytt : information från smittskyddet och mikrobiologen, 41
Open this publication in new window or tab >>Kirurgisk behandling av livshotande infektioner vardagsarbete för öronläkarna på Key-Åbergs tid
2006 (Swedish)In: Smittnytt : information från smittskyddet och mikrobiologen, Vol. 41Article in journal (Other (popular science, discussion, etc.)) Published
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-36310 (URN)30945 (Local ID)30945 (Archive number)30945 (OAI)
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2011-01-11
Rask-Andersen, H., Friberg, U., Bagger-Sjöbäck, D., Hessén-Söderman, A.-C., Bergenius, J., Idrizbegovic, E., . . . Stjernschantz, J. (2006). Randomized, Double-Blind, Placebo-Controlled, Dose-Titration Study with Latanoprost Salt in Meniere´s Disease. In: Association for research in otolaryngology,2006 (pp. 331-331).
Open this publication in new window or tab >>Randomized, Double-Blind, Placebo-Controlled, Dose-Titration Study with Latanoprost Salt in Meniere´s Disease
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2006 (English)In: Association for research in otolaryngology,2006, 2006, p. 331-331Conference paper, Published paper (Other academic)
Abstract [en]

   

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-36832 (URN)32710 (Local ID)32710 (Archive number)32710 (OAI)
Available from: 2009-10-10 Created: 2009-10-10
Hydén, D. & Gejrot, T. (2005). Hans Key-Åberg - Linköpings förste öronklinikchef, militärläkare och författare med intressant släkthistoria. Operatör i Lennart Nilssons första medicinska fotoreportage. Svensk medicinhistorisk tidskrift, 9, 115-120
Open this publication in new window or tab >>Hans Key-Åberg - Linköpings förste öronklinikchef, militärläkare och författare med intressant släkthistoria. Operatör i Lennart Nilssons första medicinska fotoreportage
2005 (Swedish)In: Svensk medicinhistorisk tidskrift, ISSN 1402-9871, Vol. 9, p. 115-120Article in journal (Other academic) Published
Abstract [sv]

   

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-35995 (URN)29270 (Local ID)29270 (Archive number)29270 (OAI)
Available from: 2009-10-10 Created: 2009-10-10 Last updated: 2011-01-12
Hydén, D. (2003). Bror Hjort bejakade livet trots stort hörselhandikapp efter tuberkulos i ungdomen. Läkartidningen, 100, 2304-2306
Open this publication in new window or tab >>Bror Hjort bejakade livet trots stort hörselhandikapp efter tuberkulos i ungdomen
2003 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 100, p. 2304-2306Article in journal (Other (popular science, discussion, etc.)) Published
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-28005 (URN)12765 (Local ID)12765 (Archive number)12765 (OAI)
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2017-12-13
Samuelsson, A.-K., Hydén, D., Roberg, M. & Skogh, T. (2003). Evaluation of anti-hsp70 antibody screening in sudden deafness. Ear and Hearing, 24(3), 233-235
Open this publication in new window or tab >>Evaluation of anti-hsp70 antibody screening in sudden deafness
2003 (English)In: Ear and Hearing, ISSN 0196-0202, E-ISSN 1538-4667, Vol. 24, no 3, p. 233-235Article in journal (Refereed) Published
Abstract [en]

Objective: To assess the diagnostic utility of anti-hsp70 antibody screening in sudden deafness. Design: Sera from 27 patients with sudden deafness and 100 healthy blood donors were analyzed by Western blotting (WB) for the presence of antibodies against 68 kD heat shock protein (anti-hsp70). Results: 19% of the patient sera and 14% of the control sera turned out positive, which was not significantly different. Conclusions: The anti-hsp70 WB test lacks clinical utility for diagnostic screening in patients with sudden deafness.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-26564 (URN)10.1097/01.AUD.0000069230.36940.AC (DOI)11126 (Local ID)11126 (Archive number)11126 (OAI)
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2017-12-13
Gejrot, T. & Hydén, D. (2002). Apropå otologins profiler. Svensk ÖNH tidskrift, 9, 17-17
Open this publication in new window or tab >>Apropå otologins profiler
2002 (Swedish)In: Svensk ÖNH tidskrift, ISSN 1400-0121, Vol. 9, p. 17-17Article in journal (Other (popular science, discussion, etc.)) Published
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-28004 (URN)12764 (Local ID)12764 (Archive number)12764 (OAI)
Available from: 2009-10-08 Created: 2009-10-08 Last updated: 2011-01-13
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