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Cassel, Petra
Publications (2 of 2) Show all publications
Eriksson, P., Andersson, C., Cassel, P., Nyström, S. & Ernerudh, J. (2015). Letter: Increase in Th17-associated CCL20 and decrease in Th2-associated CCL22 plasma chemokines in active ANCA-associated vasculitis [Letter to the editor]. Scandinavian Journal of Rheumatology, 44(1), 80-83
Open this publication in new window or tab >>Letter: Increase in Th17-associated CCL20 and decrease in Th2-associated CCL22 plasma chemokines in active ANCA-associated vasculitis
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2015 (English)In: Scandinavian Journal of Rheumatology, ISSN 0300-9742, E-ISSN 1502-7732, Vol. 44, no 1, p. 80-83Article in journal, Letter (Other academic) Published
Abstract [en]

n/a

Place, publisher, year, edition, pages
Informa Healthcare, 2015
National Category
Clinical Medicine Immunology in the medical area Other Clinical Medicine
Identifiers
urn:nbn:se:liu:diva-114016 (URN)10.3109/03009742.2014.952332 (DOI)000347408000013 ()25352172 (PubMedID)
Available from: 2015-02-06 Created: 2015-02-05 Last updated: 2020-01-16
Vrethem, M., Kvarnström, M., Stenstam, J., Cassel, P., Gustafsson, M., Landtblom, A.-M. & Ernerudh, J. (2012). Cytokine mapping in cerebrospinal fluid and blood in multiple sclerosis patients without oligoclonal bands. Multiple Sclerosis, 18(5), 669-673
Open this publication in new window or tab >>Cytokine mapping in cerebrospinal fluid and blood in multiple sclerosis patients without oligoclonal bands
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2012 (English)In: Multiple Sclerosis, ISSN 1352-4585, E-ISSN 1477-0970, Vol. 18, no 5, p. 669-673Article in journal (Refereed) Published
Abstract [en]

Objective: Since there are clinical and genetic differences between MS patients with intrathecal oligoclonal bands (OCB+ ) in the cerebrospinal fluid (CSF) compared with those without (OCB-), the aim was to find out if OCB- patients showed a different pattern of cytokine immune activation compared with OCB+ patients. Methods: The study included 25 MS patients (10 OCB- and 15 OCB+ ) and 13 controls. A panel of cytokines was measured; IL-1β, IL-6, IL-8/CXCL8, IL-10, TNF and GM-CSF in serum, CSF and in supernatants from polyclonally stimulated blood mononuclear cells, where also levels of IL-12p40, IL-13, IL-15, IL-17 and IFN-γ were measured. The concentrations of soluble (s) VCAM-1 and sCD14 were measured in serum and CSF. Results: In general, there were no extensive differences in cytokine concentrations between the OCB- and OCB+ groups. Conclusion: OCB- MS patients do not seem to constitute a separate entity concerning inflammatory parameters measured as cytokine concentrations in CSF and blood.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:liu:diva-75970 (URN)10.1177/1352458511424903 (DOI)000303319000107 ()21965416 (PubMedID)
Note
funding agencies|Swedish Association of Neurologically Disabled||County Council of Ostergotland||University Hospital of Linkoping||Available from: 2012-03-30 Created: 2012-03-20 Last updated: 2020-01-16
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