liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Abnormal brain processing of gentle touch in anorexia nervosa
Univ Gothenburg, Sweden.
Univ Gothenburg, Sweden.
Univ Gothenburg, Sweden; Sahlgrens Univ Hosp, Sweden.
Univ Gothenburg, Sweden.
Show others and affiliations
2018 (English)In: Psychiatry Research: Neuroimaging, ISSN 0925-4927, E-ISSN 1872-7506, Vol. 281, p. 53-60Article in journal (Refereed) Published
Abstract [en]

Body image disturbance is a core symptom in anorexia nervosa (AN). Recent research suggests that abnormalities in touch perception may contribute to the disease mechanisms in AN. Here, we used functional magnetic resonance imaging (fMRI) to study possible abnormalities in cortical processing of affective touch in AN. Gentle skin strokes were applied to the right forearm during fMRI scanning in women diagnosed with AN (n = 25) and in matched healthy controls (HC; n = 25). Blocks of skin stroking were alternated with blocks of static skin indentation. Participants provided ratings of the pleasantness of skin stroking stimulation. AN participants perceived skin stroking as significantly less pleasant than HC. We observed no group differences for the contrast between skin stroking and skin indentation in primary tactile regions. We did find, however, significantly less activity in the AN group in areas including left caudate nucleus. Also, we found less activity in the AN group in bilateral lateral occipital cortex for the main effect of skin stroking. Our results suggest that abnormal functioning of the dorsal striatum could affect evaluation of pleasant tactile stimuli, and that abnormal functioning of the lateral occipital cortex might be related to disturbed body image perception.

Place, publisher, year, edition, pages
ELSEVIER IRELAND LTD , 2018. Vol. 281, p. 53-60
Keywords [en]
Anorexia nervosa; Touch; fMRI; Dorsal striatum; Lateral occipital cortex
National Category
Neurology
Identifiers
URN: urn:nbn:se:liu:diva-152592DOI: 10.1016/j.pscychresns.2018.08.007ISI: 000448020100008PubMedID: 30248526OAI: oai:DiVA.org:liu-152592DiVA, id: diva2:1262139
Note

Funding Agencies|European Union Seventh Framework Program (FP7/2007-2013) [PIOF-GA-2012-302896]; Soderstrom Konig Foundation; Linnea and Joself Carlssons Foundation; Fredrik och Ingrid Thuring Foundation; O. E. och Edla Johanssons Foundation; Stiftelsen Wilhelm och Martina Lundgrens vetenskapsfond; ALF Vastra Gotaland

Available from: 2018-11-09 Created: 2018-11-09 Last updated: 2019-05-01

Open Access in DiVA

fulltext(807 kB)72 downloads
File information
File name FULLTEXT01.pdfFile size 807 kBChecksum SHA-512
25795dea698c35f8c42ef4eee806b97ae2c78129b628f842d74cef46159d2544a2f7c9727fa91d4dba664ea2cf759b20c7671076a8d13609183f83c12649612d
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Olausson, Håkan

Search in DiVA

By author/editor
Björnsdotter Åberg, MalinOlausson, Håkan
By organisation
Center for Social and Affective NeuroscienceFaculty of Medicine and Health SciencesDepartment of Clinical Neurophysiology
In the same journal
Psychiatry Research: Neuroimaging
Neurology

Search outside of DiVA

GoogleGoogle Scholar
Total: 72 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 139 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf