Unexpected gender bias among organ donors in Sweden during 2009-2013. A nationwide observational study.
2015 (English)In: Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, E-ISSN 1399-6576, Vol. 59, no Suppl. 121, article id O13-09Article in journal, Meeting abstract (Other academic) Published
Abstract [en]
Introduction: The gap between the number of organ donors and patients on waiting lists for transplantation is wide globally. Understanding reasons for variation in organ donation between and within countries may lead to increased availability of organs for transplantation. The purpose of the present analysis was to examine age and gender of organ donors in Sweden.
Methods: All deaths in Swedish ICUs during 2009–2013 were examined using a prospectively determined protocol comprising 10 primary questions. Protocols were sent electronically to the Swed- ish Intensive Care Registry (SIR) for validation and then joined with the appropriate ICU admission in the SIR database. The rela- tionship between organ donation and gender was analysed using logistic regression adjusted for age and comorbidities (as defined in the SAPS3 model) and presented as odds ratios (OR).
Results: The female to male ratio (F/M) was 0.72 in ICU admissions and ICU deaths, while the organ donor F/M was 1.06. Almost all organ donors (98%) were found in 4 major diagnostic groups which all showed a disproportionate high female donor rate (Table). Mean age in female organ donors was 54.9 (SD 16.5) years. and in men 53.5 (18.3) years, P = 0.48. The crude female OR for becoming a donor was 1.47 (95% CI: 1.25–1.74, P < 0.001), and the adjusted OR was 1.55 (95% CI: 1.28–1.88, P < 0.001).
Table 1 Source: https://www.eventure-online.com/parthen-uploads/154/SSAI/img1_264985_Nxx2LShLTc.jpg.
Conclusion: During the critical pathway for organ donation after brain death the F/M ratio unexpectedly rose. Why and when men became underrepresented in this pathway needs further study.
Place, publisher, year, edition, pages
Wiley-Blackwell, 2015. Vol. 59, no Suppl. 121, article id O13-09
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-125567DOI: 10.1111/aas.12556OAI: oai:DiVA.org:liu-125567DiVA, id: diva2:907061
Conference
33rd Congress of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine, Matters of the heart, Reykavik, Iceland, 10-12 June 2015
2016-02-262016-02-262021-10-04Bibliographically approved