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High levels of isocyanic acid in smoke generated during hot iron cauterization
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för neuro- och inflammationsvetenskap. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Hjärt- och Medicincentrum, Arbets- och miljömedicin.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för neuro- och inflammationsvetenskap. Linköpings universitet, Medicinska fakulteten.
2019 (engelsk)Inngår i: Archives of Environmental & Occupational Health, ISSN 1933-8244, E-ISSN 2154-4700Artikkel i tidsskrift (Fagfellevurdert) Epub ahead of print
Abstract [en]

Pyrolysis of nitrogen containing biofuels generates isocyanic acid (ICA) and we here studied if ICA also is present in cauterization smoke. Air sampling was performed when animal technicians that had developed airway symptoms worked with dehorning. Tissue heated in a laboratory model was used to mimic cauterization. ICA in air at the workplace exceeded 10 times the national exposure limit. In the laboratory, the ICA generated per mg tissue from heated hair, horn and nail was 13.9 +/- 7.8, 24.0 +/- 4.1 and 32.0 +/- 2.9 mu g, respectively. Three workers were medically examined and two were diagnosed with asthma and a third had severe airway problem that resembled asthma. The study shows that high levels of ICA are generated during cauterization of nitrogen-containing tissue. If this could trigger airway symptoms deserves to be investigated further.

sted, utgiver, år, opplag, sider
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD , 2019.
Emneord [en]
Asthma; dehorning; hydrogen cyanide; hot shoeing; isocyanates; particles; surgical smoke
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-158587DOI: 10.1080/19338244.2019.1593920ISI: 000470430700001PubMedID: 31070514OAI: oai:DiVA.org:liu-158587DiVA, id: diva2:1334794
Merknad

Funding Agencies|County Council of Ostergotland Sweden [LIO-677581, LIO-702611]

Tilgjengelig fra: 2019-07-03 Laget: 2019-07-03 Sist oppdatert: 2019-07-03

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