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Pigment epithelial changes in a strain of pigmented rabbits with low ERG b-wave amplitudes
Linköpings universitet, Hälsouniversitetet. Linköpings universitet, Institutionen för nervsystem och rörelseorgan, Oftalmologi. Östergötlands Läns Landsting, Rekonstruktionscentrum, Ögonkliniken US.
2004 (engelsk)Inngår i: Vision Research, ISSN 0042-6989, E-ISSN 1878-5646, Vol. 44, nr 1, s. 99-102Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Retinas from a strain of rabbits with low dark-adapted electroretinographic (ERG) b-wave amplitudes, and declining ERG responses with time, were examined by light and electron microscopy. Seven rabbits from the affected strain (13 months to 5 years old) and six control animals (6-26 months old) were included in the study. Small inclusions with an electron dense border, about 0.2-1.5 μm in diameter, were significantly (p<0.01) more numerous within the retinal pigment epithelial (RPE) cells in the affected rabbits than in the control animals. No morphological evidence of retinal degeneration was found. Further studies are needed to establish the functional defect in this strain of rabbits.

sted, utgiver, år, opplag, sider
2004. Vol. 44, nr 1, s. 99-102
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URN: urn:nbn:se:liu:diva-24729DOI: 10.1016/j.visres.2003.08.003Lokal ID: 6979OAI: oai:DiVA.org:liu-24729DiVA, id: diva2:245052
Tilgjengelig fra: 2009-10-07 Laget: 2009-10-07 Sist oppdatert: 2017-12-13

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