liu.seSearch for publications in DiVA
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Evaluation of right and left ventricular function using speckle tracking echocardiography in patients with arrhythmogenic right ventricular cardiomyopathy and their first degree relatives
Linköpings universitet, Institutionen för medicin och hälsa, Klinisk fysiologi. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Hjärt- och Medicincentrum, Fysiologiska kliniken US.
Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för kardiovaskulär medicin. Linköpings universitet, Hälsouniversitetet.
Kalmar County Hospital, Sweden .
Linköpings universitet, Institutionen för medicin och hälsa, Klinisk fysiologi. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Hjärt- och Medicincentrum, Fysiologiska kliniken US.
2012 (engelsk)Inngår i: Cardiovascular Ultrasound, ISSN 1476-7120, E-ISSN 1476-7120, Vol. 10, nr 37Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Introduction and aim: The identification of right ventricular abnormalities in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) in early stages is still difficult. The aim of this study was to investigate if longitudinal strain based on speckle tracking can detect subtle right (RV) or left ventricular (LV) dysfunction as an early sign of ARVC. Methods and results: Seventeen male patients, fulfilling Task force criteria for ARVC, 49 (32-70) years old, nineteen male first degree relatives 29 (19-73) y.o. and twenty-two healthy male volunteers 36 (24-66) y.o participated in the study. Twelve-lead and signal-averaged electrocardiograms were recorded. All subjects underwent echocardiography. LV and RV diameters, peak systolic velocity from tissue Doppler and longitudinal strain based on speckle tracking were measured from the basal and mid segments in both ventricles. RV longitudinal strain measurement was successful in first degree relatives and controls (95 resp. 86%) but less feasible in patients (59%). Results were not systematically different between first degree relatives and controls. Using discriminant analysis, we then developed an index based on echocardiographic parameters. All normal controls had an index less thanl while patients with abnormal ventricles had an index between 1-4. Some of the first degree relatives deviated from the normal pattern. Conclusion: Longitudinal strain of LV and RV segments was significantly lower in patients than in relatives and controls. An index was developed incorporating dimensional and functional echocardiographic parameters. In combination with genetic testing this index might help to detect early phenotype expression in mutation carriers.

sted, utgiver, år, opplag, sider
BioMed Central , 2012. Vol. 10, nr 37
Emneord [en]
Arrhythmogenic right ventricular cardiomyopathy; Right ventricle; Strain; Echocardiography; Right ventricular function
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-87233DOI: 10.1186/1476-7120-10-37ISI: 000311800000001OAI: oai:DiVA.org:liu-87233DiVA, id: diva2:587341
Tilgjengelig fra: 2013-01-14 Laget: 2013-01-14 Sist oppdatert: 2017-12-06bibliografisk kontrollert

Open Access i DiVA

fulltext(1927 kB)406 nedlastinger
Filinformasjon
Fil FULLTEXT01.pdfFilstørrelse 1927 kBChecksum SHA-512
9037b4c3eeb21a890fe61495c31e645bd80d8784ffd570450b517ba59e080ed26db7ce7cb4d8b7a2f1e5da1271075efcd1c97ccfc8b02585cc18f46e219551bf
Type fulltextMimetype application/pdf

Andre lenker

Forlagets fulltekst

Personposter BETA

Åström, Meriam AneqEngvall, JanNylander, Eva

Søk i DiVA

Av forfatter/redaktør
Åström, Meriam AneqEngvall, JanNylander, Eva
Av organisasjonen
I samme tidsskrift
Cardiovascular Ultrasound

Søk utenfor DiVA

GoogleGoogle Scholar
Totalt: 406 nedlastinger
Antall nedlastinger er summen av alle nedlastinger av alle fulltekster. Det kan for eksempel være tidligere versjoner som er ikke lenger tilgjengelige

doi
urn-nbn

Altmetric

doi
urn-nbn
Totalt: 246 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf