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Cornea Regeneration as an Alternative to Human Donor Transplantation
University of Montreal, Canada.
University of Ottawa Heart Institute, Canada.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för cellbiologi. Linköpings universitet, Medicinska fakulteten.ORCID-id: 0000-0003-1222-6720
2015 (engelsk)Inngår i: European Ophthalmic Review, ISSN 1756-1795, Vol. 9, nr 2, s. 111-114Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

There is a need for an alternative to human donor corneas as the availability of good-quality tissues remains limited, with this situation potentially worsening as the population in many countries is progressively ageing. There have been numerous attempts to develop corneal equivalent as alternatives to donated human corneas as well as prostheses. In this short review, we focus on the efforts in bioengineering implants that promote regeneration by Canadian researchers, including our current team of authors. The examples of technologies developed that we describe include biomaterials that allow for partial regeneration of corneal tissue, self-assembled cornea constructs and cell-free corneal implants that promoted regeneration when evaluated in clinical trials in Europe.

sted, utgiver, år, opplag, sider
touchOPHTHALMOLOGY.com , 2015. Vol. 9, nr 2, s. 111-114
Emneord [en]
Cornea, biomaterials, prostheses, regeneration, self-assembly, implants, clinical studies
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-126611DOI: 10.17925/EOR.2015.09.02.111OAI: oai:DiVA.org:liu-126611DiVA, id: diva2:915882
Tilgjengelig fra: 2016-03-31 Laget: 2016-03-31 Sist oppdatert: 2016-04-20bibliografisk kontrollert

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