liu.seSök publikationer i DiVA
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
Division of Dentistry, University of Manchester , Manchester , UK; Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway; Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway..
Cleft Palate Center , Aarhus , Denmark.
Department of Orthodontics , Sahlgrenska Academy, University of Gothenburg , Sweden.
Region Östergötland, Sinnescentrum, Käkkliniken US.
Visa övriga samt affilieringar
2017 (Engelska)Ingår i: Journal of Plastic Surgery and Hand Surgery, ISSN 2000-656X, E-ISSN 2000-6764, Vol. 51, nr 1, s. 2-13Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

BACKGROUND AND AIMS: Longstanding uncertainty surrounds the selection of surgical protocols for the closure of unilateral cleft lip and palate, and randomised trials have only rarely been performed. This paper is an introduction to three randomised trials of primary surgery for children born with complete unilateral cleft lip and palate (UCLP). It presents the protocol developed for the trials in CONSORT format, and describes the management structure that was developed to achieve the long-term engagement and commitment required to complete the project.

METHOD: Ten established national or regional cleft centres participated. Lip and soft palate closure at 3-4 months, and hard palate closure at 12 months served as a common method in each trial. Trial 1 compared this with hard palate closure at 36 months. Trial 2 compared it with lip closure at 3-4 months and hard and soft palate closure at 12 months. Trial 3 compared it with lip and hard palate closure at 3-4 months and soft palate closure at 12 months. The primary outcomes were speech and dentofacial development, with a series of perioperative and longer-term secondary outcomes.

RESULTS: Recruitment of 448 infants took place over a 9-year period, with 99.8% subsequent retention at 5 years.

CONCLUSION: The series of reports that follow this introductory paper include comparisons at age 5 of surgical outcomes, speech outcomes, measures of dentofacial development and appearance, and parental satisfaction. The outcomes recorded and the numbers analysed for each outcome and time point are described in the series.

TRIAL REGISTRATION: ISRCTN29932826.

Ort, förlag, år, upplaga, sidor
Taylor & Francis, 2017. Vol. 51, nr 1, s. 2-13
Nyckelord [en]
Scandcleft Project, multicentre study, randomised controlled trials, surgery for unilateral complete cleft lip and palate
Nationell ämneskategori
Kirurgi
Identifikatorer
URN: urn:nbn:se:liu:diva-135511DOI: 10.1080/2000656X.2016.1263202ISI: 000395170100002PubMedID: 28218559OAI: oai:DiVA.org:liu-135511DiVA, id: diva2:1082360
Anmärkning

Funding agencies: University of Manchester; University Hospital Rikshospitalet; Statped sorost, Oslo; European Commission Biomed II Programme; European Commission Framework V Programme; Swedish Research Council for Health, Working Life and Welfare [2011-1443]

Tillgänglig från: 2017-03-16 Skapad: 2017-03-16 Senast uppdaterad: 2018-05-07

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Lundeborg, IngerMarcusson, Agneta

Sök vidare i DiVA

Av författaren/redaktören
Paulin, GunnarBerggren, AndersLundeborg, IngerMarcusson, AgnetaMjönes, Anna-Britta
Av organisationen
Käkkliniken USHand- och plastikkirurgiska kliniken USAvdelningen för Logopedi, Audiologi och OtorhinolaryngologiMedicinska fakultetenAvdelningen för Kirurgi, Ortopedi och OnkologiÖron- näsa- och halskliniken US
I samma tidskrift
Journal of Plastic Surgery and Hand Surgery
Kirurgi

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 242 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf