liu.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Increased stiffness of the abdominal aorta in women with rheumatoid arthritis
Visa övriga samt affilieringar
2005 (Engelska)Ingår i: Rheumatology, ISSN 1462-0324, E-ISSN 1462-0332, Vol. 44, nr 7, 896-901 s.Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Objective. To study the distensibility and the diameter of the abdominal aorta and the common carotid artery (CCA) in patients with rheumatoid arthritis (RA), and investigate the relation between mechanical properties of these arteries and disease severity. Methods. One hundred and one patients with RA (33 consecutive cases with extra-articular manifestations, and 68 subjects with non-extra-articular disease, matched for age, sex and disease duration) were investigated. Echo-tracking ultrasonography was used to measure stiffness and mean diameter of the abdominal aorta and the CCA. The patients were compared with healthy individuals from the corresponding age group (n=74 for measurements of the aorta, n = 64 for the CCA). Predicted values for stiffness and mean diameter, based on age and sex, were calculated. Results. Stiffness of the abdominal aorta was increased in women with RA [mean percentage of predicted value (% predicted) 180, 95% confidence interval (95% CI) 150-211] but not in men (% predicted 99, 95% CI 75-122). CCA stiffness was less markedly increased, and mean diameters of the aorta and the CCA were not different from the expected. In the RA cohort, patients with extra-articular manifestations tended to have greater stiffness of the aorta (P = 0.11), and disability, as indicated by a higher Health Assessment Questionnaire score, was associated with increased aortic stiffness (P = 0.04). Conclusion. RA is associated with decreased distensibility of the abdominal aorta in females, and such changes seem to correlate with disease severity. We suggest that arterial stiffness is an important factor in cardiovascular co-morbidity in RA. © The Author 2005. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved.

Ort, förlag, år, upplaga, sidor
2005. Vol. 44, nr 7, 896-901 s.
Nyckelord [en]
rheumatoid arthritis, arterial distensibility, ultrasound, aorta, cardiovascular disease, extra-articular manifestations
Nationell ämneskategori
Medicin och hälsovetenskap
Identifikatorer
URN: urn:nbn:se:liu:diva-30086DOI: 10.1093/rheumatology/keh607Lokalt ID: 15554OAI: oai:DiVA.org:liu-30086DiVA: diva2:250907
Tillgänglig från: 2009-10-09 Skapad: 2009-10-09 Senast uppdaterad: 2017-12-13

Open Access i DiVA

Fulltext saknas

Övriga länkar

Förlagets fulltext

Personposter BETA

Länne, Toste

Sök vidare i DiVA

Av författaren/redaktören
Länne, Toste
Av organisationen
HälsouniversitetetKlinisk fysiologiThorax-kärlkliniken
I samma tidskrift
Rheumatology
Medicin och hälsovetenskap

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetricpoäng

doi
urn-nbn
Totalt: 59 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf