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Clinical epidemiology of Guillain-Barré syndrome in adults in Sweden 1996-97: A prospective study
Division of Neurology, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden, Division of Neurology, Huddinge University Hospital, S-141 86 Huddinge, Sweden.
Division of Neurology, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden.
Division of Neurology, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden.
Department of Neurology, Karolinska Hospital, Stockholm, Sweden.
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2000 (Engelska)Ingår i: European Journal of Neurology, ISSN 1351-5101, E-ISSN 1468-1331, Vol. 7, nr 6, s. 685-692Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

We described clinical manifestations, outcomes, prognostic indicators and clinico-epidemiological subgroups for 53 adult patients with Guillain-Barré syndrome (GBS) in Sweden during the period 1996-97. These patients were identified from a population of 2.8 million inhabitants and prospectively followed up for one year by a network of neurologists. An additional 10 cases, of whom five were adults who had not been prospectively followed up, were not included in the analyses. At 6 months after onset 80% of the patients could walk without aid, while at 1 year 46% were fully recovered, 42% had mild residual signs or symptoms, 4% had moderate and 6% severe disabilities, and 2% had died. Intravenous human immunoglobulin or plasmapheresis were used in 72% of the patients. The sum of the Medical Research Council (MRC) score at nadir was found as the only significant predictor for residual signs at 1 year in a multivariate model. Three subgroups, with different clinico-epidemiological characteristics, were identified by using cluster analysis. In conclusion, GBS in Sweden is frequently preceded by a respiratory infection, is often treated with immunomodulatory therapies, and exhibits a high recovery rate and a low fatality rate.

Ort, förlag, år, upplaga, sidor
2000. Vol. 7, nr 6, s. 685-692
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Naturvetenskap
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URN: urn:nbn:se:liu:diva-47536DOI: 10.1046/j.1468-1331.2000.00128.xOAI: oai:DiVA.org:liu-47536DiVA, id: diva2:268432
Tillgänglig från: 2009-10-11 Skapad: 2009-10-11 Senast uppdaterad: 2017-12-13

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