liu.seSök publikationer i DiVA
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Prolongation of the ejaculation latency in the male rat by thioridazine and chlorimipramine.
Göteborgs universitet.
Göteborgs universitet. (Psykologi)ORCID-id: 0000-0001-5025-9975
Göteborgs universitet.
1979 (Engelska)Ingår i: Psychopharmacology, ISSN 0033-3158, E-ISSN 1432-2072, Vol. 65, nr 2, s. 137-140Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Thioridazine (3 mg/kg) and chlorimipramine (1.5–6.0 mg/kg) prolonged the ejaculation latency and increased the number of mounts but did not change the number of intromissions preceding ejaculation. Blockade of peripheral and central noradrenaline receptors by phentolamine and phenoxybenzamine respectively resulted in a suppression of all aspects of the sexual behavior with increasing doses. dl-5-HTP (25–100 mg/kg) in combination with an inhibitor of peripheral 5-HTP decarboxylase (benserazide, 25 mg/kg) produced, like chlorimipramine and thioridazine, a prolongation of ejaculation latency and an increase in the number of mounts preceding ejaculation. Selective inhibition of 5-HT reuptake however, by zimelidine (0–20 mg/kg) or alaproclate (0–20 mg/kg) did not affect the mating behavior. At higher doses of these drugs some animals failed to initiate sexual activities. There was an increase in the postejaculatory interval but no change in the ejaculatory latency.It is concluded that the prolonged ejaculation latencies observed following treatment with thioridazine or chlorimipramine is not due to a blockade of central or peripheral adrenergic -receptors.

Ort, förlag, år, upplaga, sidor
1979. Vol. 65, nr 2, s. 137-140
Nyckelord [en]
Male sexual behavior, Rat, Monoamines, Thioridazine, Chlorimipramine
Nationell ämneskategori
Psykologi (exklusive tillämpad psykologi) Farmakologi och toxikologi
Identifikatorer
URN: urn:nbn:se:liu:diva-80872DOI: 10.1007/BF00433039OAI: oai:DiVA.org:liu-80872DiVA, id: diva2:548886
Tillgänglig från: 2012-09-02 Skapad: 2012-09-02 Senast uppdaterad: 2018-03-14

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltext

Personposter BETA

Heimann, Mikael

Sök vidare i DiVA

Av författaren/redaktören
Heimann, Mikael
I samma tidskrift
Psychopharmacology
Psykologi (exklusive tillämpad psykologi)Farmakologi och toxikologi

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetricpoäng

doi
urn-nbn
Totalt: 696 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf