liu.seSök publikationer i DiVA
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Glucose Homeostasis Variables in Pregnancy versus Maternal and Infant Body Composition
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.ORCID-id: 0000-0003-2482-7048
Karolinska Institute, Sweden.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten.
2015 (Engelska)Ingår i: Nutrients, ISSN 2072-6643, E-ISSN 2072-6643, Vol. 7, nr 7, s. 5615-5627Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Intrauterine factors influence infant size and body composition but the mechanisms involved are to a large extent unknown. We studied relationships between the body composition of pregnant women and variables related to their glucose homeostasis, i.e., glucose, HOMA-IR (homeostasis model assessment-insulin resistance), hemoglobin A(1c) and IGFBP-1 (insulin-like growth factor binding protein-1), and related these variables to the body composition of their infants. Body composition of 209 women in gestational week 32 and of their healthy, singleton and full-term one-week-old infants was measured using air displacement plethysmography. Glucose homeostasis variables were assessed in gestational week 32. HOMA-IR was positively related to fat mass index and fat mass (r(2) = 0.32, p less than 0.001) of the women. Maternal glucose and HOMA-IR values were positively (p 0.006) associated, while IGFBP-1was negatively (p = 0.001) associated, with infant fat mass. HOMA-IR was positively associated with fat mass of daughters (p less than 0.001), but not of sons (p = 0.65) (Sex-interaction: p = 0.042). In conclusion, glucose homeostasis variables of pregnant women are related to their own body composition and to that of their infants. The results suggest that a previously identified relationship between fat mass of mothers and daughters is mediated by maternal insulin resistance.

Ort, förlag, år, upplaga, sidor
MDPI , 2015. Vol. 7, nr 7, s. 5615-5627
Nyckelord [en]
body composition; infant; insulin resistance; pregnancy; sex difference
Nationell ämneskategori
Klinisk medicin
Identifikatorer
URN: urn:nbn:se:liu:diva-121143DOI: 10.3390/nu7075243ISI: 000359349800033PubMedID: 26184296OAI: oai:DiVA.org:liu-121143DiVA, id: diva2:852262
Anmärkning

Funding Agencies|Swedish Research Council [15402]; Swedish Research Council Formas [2008-1332, 2006-614]; Medical Faculty, Linkoping University; County Council of Ostergotland

Tillgänglig från: 2015-09-08 Skapad: 2015-09-08 Senast uppdaterad: 2019-06-28

Open Access i DiVA

fulltext(354 kB)136 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 354 kBChecksumma SHA-512
d34e28c2f3c8b7c74263864c7da0dcc8b8922fcd0004355cd385b026a1f6c484db5823dd70b80e01a1fb1cd5a05d62c2e4c3a99884e06b05bce81de0f7f352ab
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Henriksson, PontusForsum, Elisabet

Sök vidare i DiVA

Av författaren/redaktören
Henriksson, PontusForsum, Elisabet
Av organisationen
Avdelningen för kliniska vetenskaperMedicinska fakulteten
I samma tidskrift
Nutrients
Klinisk medicin

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 136 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 152 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf