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Author:
Holm, Åsa (Linköping University, Department of Mathematics) (Linköping University, The Institute of Technology)
Larsson, Torbjörn (Linköping University, Department of Mathematics, Optimization ) (Linköping University, The Institute of Technology)
Carlsson Tedgren, Åsa (Linköping University, Department of Medical and Health Sciences, Radiation Physics) (Linköping University, Faculty of Health Sciences) (Östergötlands Läns Landsting, Centre for Surgery, Orthopaedics and Cancer Treatment, Department of Radiation Physics UHL)
Title:
On the Correlation Between DVH Parameters and Linear Penalties in Optimization of HDR Prostate Brachytherapy Dose Plans
Department:
Linköping University, Faculty of Health Sciences
Linköping University, Department of Mathematics
Linköping University, Department of Medical and Health Sciences, Radiation Physics
Linköping University, Department of Mathematics, Optimization
Östergötlands Läns Landsting, Centre for Surgery, Orthopaedics and Cancer Treatment, Department of Radiation Physics UHL
Linköping University, The Institute of Technology
Publication type:
Manuscript (preprint) (Other academic)
Language:
English
URI:
urn:nbn:se:liu:diva-67789
Permanent link:
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-67789
Subject category:
Mathematics
SVEP category:
MATHEMATICS
Abstract(en) :

When optimizing dwell times for HDR brachytherapy it is common to use a model comprising an objective of linear penalties. However whether a planis considered good or not depends on other measures such as DVH-based parameters. We show through experiments that the correlation between the value of the objective function and the values of DVH-based parameters, such as D90, is weak in some cases. It seems that the objective function can only classify solutions into better or worse, however it can not distinguish the best with respect to DVH-based parameters.

Available from:
2011-04-26
Created:
2011-04-26
Last updated:
2011-04-26
Statistics:
35 hits
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