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Skin regeneration in three dimensions, current status, challenges and opportunities
Sharjah Institute for Medical Research and College of Medicine, University of Sharjah, Sharjah, UAE(a); Faculty of Medicine, Suez Canal University, Egypt.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Kirurgi, Ortopedi och Onkologi. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Sinnescentrum, Hand- och plastikkirurgiska kliniken US. Division of Experimental Cancer Medicine, Faculty of MDepartment of Laboratory Medicine, Karolinska Institutet, Sweden .
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Kirurgi, Ortopedi och Onkologi. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Sinnescentrum, Hand- och plastikkirurgiska kliniken US. Plastic Surgery Unit, Surgery Department, Suez Canal University, Egypt.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för Kirurgi, Ortopedi och Onkologi. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Sinnescentrum, Hand- och plastikkirurgiska kliniken US.
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2017 (engelsk)Inngår i: Differentiation, ISSN 0301-4681, E-ISSN 1432-0436, Vol. 96, s. 4s. 26-29Artikkel, forskningsoversikt (Fagfellevurdert) Published
Abstract [en]

Skin regeneration is a life-saving need for many patients, whom list is stretched from burn victims to motor-car accidents. Spraying cells, either keratinocytes or stem cells, were associated with variable results and, in many cases, unfavorable outcomes. As the spatial configuration of the skin is distinctive, many trials investigated the bio-printing or the construction of three dimensional skin models where different layers of the skin were preserved. Although some of these models showed the histological configuration of the skin, their acceptance by the wound was questionable as a consequence of delayed vascularization. In this mini-review, different models for three dimensional regeneration of the skin will be discussed with their main points of strength and challenges as well as their possible opportunities.

sted, utgiver, år, opplag, sider
Elsevier, 2017. Vol. 96, s. 4s. 26-29
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Identifikatorer
URN: urn:nbn:se:liu:diva-138673DOI: 10.1016/j.diff.2017.06.002ISI: 000415964800003PubMedID: 28628852OAI: oai:DiVA.org:liu-138673DiVA, id: diva2:1112885
Tilgjengelig fra: 2017-06-20 Laget: 2017-06-20 Sist oppdatert: 2018-03-28

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