liu.seSearch for publications in DiVA
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
The relationship between forearm skin speed-resolved perfusion and oxygen saturation, and finger arterial pulsation amplitudes, as indirect measures of endothelial function
Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för omvårdnad. Linköpings universitet, Medicinska fakulteten.ORCID-id: 0000-0002-9663-3720
CNR Inst Clin Physiol, Italy.
CNR Inst Clin Physiol, Italy.
Linköpings universitet, Institutionen för medicinsk teknik, Avdelningen för medicinsk teknik. Linköpings universitet, Tekniska fakulteten.ORCID-id: 0000-0001-6385-6760
Vise andre og tillknytning
2018 (engelsk)Inngår i: Microcirculation, ISSN 1073-9688, E-ISSN 1549-8719, Vol. 25, nr 2, artikkel-id e12422Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Objective: Endothelial function is important for regulating peripheral blood flow to meet varying metabolic demands and can be measured indirectly during vascular provocations. In this study, we compared the PAT finger response (EndoPAT) after a 5-minutes arterial occlusion to that from forearm skin comprehensive microcirculation analysis (EPOS). Methods: Measurements in 16 subjects with varying cardiovascular risk factors were carried out concurrently with both methods during arterial occlusion, while forearm skin was also evaluated during local heating. Results: Peak values for EPOS skin Perf(conv) and speed-resolved total perfusion after the release of the occlusion were significantly correlated to the EndoPAT RHI (rho =.68, P = .007 and rho =.60, P = .025, respectively), mainly due to high-speed blood flow. During local heating, EPOS skin oxygen saturation, SO2, was significantly correlated to RHI (rho = .62, P =.043). This indicates that SO2 may have diagnostic value regarding endothelial function. Conclusions: We have demonstrated for the first time a significant relationship between forearm skin microcirculatory perfusion and oxygen saturation and finger PAT. Both local heating and reactive hyperemia are useful skin provocations. Further studies are needed to understand the precise regulation mechanisms of blood flow and oxygenation during these tests.

sted, utgiver, år, opplag, sider
WILEY , 2018. Vol. 25, nr 2, artikkel-id e12422
Emneord [en]
diffuse reflectance spectroscopy; endothelium; laser Doppler Flowmetry; reactive hyperemia; tissue oxygenation
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-145476DOI: 10.1111/micc.12422ISI: 000424813900002PubMedID: 29044805OAI: oai:DiVA.org:liu-145476DiVA, id: diva2:1188353
Merknad

Funding Agencies|European Union Seventh Framework Programme (FP7) [611516]; Fulbright Visiting Scholar grant; Swedish Governmental Agency for Innovation Systems [VINNOVA] [2016-02211]

Tilgjengelig fra: 2018-03-07 Laget: 2018-03-07 Sist oppdatert: 2018-03-07

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstPubMed

Søk i DiVA

Av forfatter/redaktør
Bergstrand, SaraLarsson, MarcusStrömberg, Tomas
Av organisasjonen
I samme tidsskrift
Microcirculation

Søk utenfor DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 279 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf