liu.seSök publikationer i DiVA
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Risk factors for anastomotic leakage following ileosigmoid or ileorectal anastomosis
Karolinska Inst, Sweden; Ersta Hosp, Sweden.
Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Centrum för kirurgi, ortopedi och cancervård, Kirurgiska kliniken US.
Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden.
Visa övriga samt affilieringar
2018 (Engelska)Ingår i: Colorectal Disease, ISSN 1462-8910, E-ISSN 1463-1318, Vol. 20, nr 4, s. 304-311Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Aim

Reconstruction with an ileosigmoidal anastomosis (ISA) or ileorectal anastomosis (IRA) is a surgical option after a subtotal colectomy. Anastomotic leakage (AL) is a problematic complication and high rates have been reported, but there is limited understanding of the risk factors involved. The aim of this study was to assess the established and potential predictors of AL following ISA and IRA.

Method

This was a retrospective cohort study including all patients who had undergone ISA or IRA at three Swedish referral centres for colorectal surgery between January 2007 and March 2015. Data regarding clinical characteristics, treatment and outcome were collected from medical records. Univariate and multivariate logistic regression models were used to determine the association between patient and treatment related factors and the cumulative incidence of AL.

Results

In total, 227 patients were included. Overall, AL was detected amongst 30 patients (13.2%). Amongst patients undergoing colectomy with synchronous ISA or IRA (one‐stage procedure), AL occurred in 23 out of 120 (19.2%) compared with seven out of 107 (6.5%) after stoma reversal with ISA or IRA (two‐stage procedure) (= 0.004). In addition, the multivariate analyses revealed a statistically significantly lower odds ratio for AL following a two‐stage procedure (OR 0.10, 95% CI 0.03–0.41, = 0.001).

Conclusions

This study confirms high rates of AL following ISA and IRA. In particular, a synchronous procedure with colectomy and ISA/IRA carries a high risk of AL.

Ort, förlag, år, upplaga, sidor
Wiley-Blackwell Publishing Inc., 2018. Vol. 20, nr 4, s. 304-311
Nyckelord [en]
Ileorectal anastomosis; anastomotic leakage; risk factors
Nationell ämneskategori
Kirurgi
Identifikatorer
URN: urn:nbn:se:liu:diva-147576DOI: 10.1111/codi.13938ISI: 000428991400008PubMedID: 29059489Scopus ID: 2-s2.0-85044722739OAI: oai:DiVA.org:liu-147576DiVA, id: diva2:1201827
Anmärkning

Funding Agencies|Stockholm Community Council; Karolinska Institutet; Bengt Ihre Foundation; Bengt Ihre Research Fellowship

Tillgänglig från: 2018-04-26 Skapad: 2018-04-26 Senast uppdaterad: 2018-05-03Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMedScopus

Sök vidare i DiVA

Av författaren/redaktören
Jung, Bärbel
Av organisationen
Avdelningen för kliniska vetenskaperMedicinska fakultetenKirurgiska kliniken US
I samma tidskrift
Colorectal Disease
Kirurgi

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 126 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf