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Gender differences in symptom presentation of ST-elevation myocardial infarction - An observational multicenter survey study
Linköpings universitet, Medicinska fakulteten. Region Östergötland, Hjärt- och Medicincentrum, Kardiologiska kliniken US. Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för kardiovaskulär medicin.
Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för omvårdnad. Linköpings universitet, Medicinska fakulteten. Norrbotten Cty Council, Sweden.
Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för omvårdnad. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Hjärt- och Medicincentrum, Kardiologiska kliniken US.ORCID-id: 0000-0002-7097-392X
Linköpings universitet, Institutionen för medicin och hälsa, Avdelningen för kardiovaskulär medicin. Linköpings universitet, Medicinska fakulteten. Region Östergötland, Hjärt- och Medicincentrum, Kardiologiska kliniken US.
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2018 (Engelska)Ingår i: International Journal of Cardiology, ISSN 0167-5273, E-ISSN 1874-1754, Vol. 264Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: Symptom presentation has been sparsely studied from a gender perspective restricting the inclusion to ST elevation myocardial infarction (STEMI) patients. Correct symptom recognition is vital in order to promptly seek care in STEMI where fast reperfusion therapy is of utmost importance. Female gender has been found associated with atypical presentation in studies on mixed MI populations but it is unclear whether this is valid also in STEMI. Objectives: We assessed whether there are gender differences in symptoms and interpretation of these in STEMI, and if this is attributable to sociodemographic and clinical factors. Methods: SymTime was a multicenter observational study including a validated questionnaire and data from medical records. Eligible STEMI patients (n = 532) were enrolled within 24 h after admittance at five Swedish hospitals. Results: Women were older, more often single and had lower educational level. Chest pain was less prevalent in women (74 vs 93%, p amp;lt; 0.001), whereas shoulder (33 vs 15%, p amp;lt; 0.001), throat/neck (34 vs 18%, p amp;lt; 0.001), back pain (29 versus 12%, p amp;lt; 0.001) and nausea (49 vs 29%, p amp;lt; 0.001) were more prevalent. Women less often interpreted their symptoms as of cardiac origin (60 vs 69%, p = 0.04). Female gender was the strongest independent predictor of non-chest pain presentation, odds ratio 5.29, 95% confidence interval 2.85-9.80. Conclusions: A striking gender difference in STEMI symptoms was found. As women significantly misinterpreted their symptoms more often, it is vital when informing about MI to the society or to high risk individuals, to highlight also other symptoms than just chest pain. (C) 2018 Elsevier B.V. All rights reserved.

Ort, förlag, år, upplaga, sidor
ELSEVIER IRELAND LTD , 2018. Vol. 264
Nyckelord [en]
ST-elevation myocardial infarction; Gender; Clinical presentation; Symptoms; Chest pain
Nationell ämneskategori
Allmänmedicin
Identifikatorer
URN: urn:nbn:se:liu:diva-148360DOI: 10.1016/j.ijcard.2018.03.084ISI: 000432918500002PubMedID: 29642997OAI: oai:DiVA.org:liu-148360DiVA, id: diva2:1219068
Anmärkning

Funding Agencies|Medical Research Council of South-east Sweden (FORSS); County Council of Ostergotland; County Council of Norrbotten

Tillgänglig från: 2018-06-15 Skapad: 2018-06-15 Senast uppdaterad: 2019-05-02

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Sederholm Lawesson, SofiaEricsson, Maria

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Sederholm Lawesson, SofiaIsaksson, Rose-MarieThylén, IngelaEricsson, MariaSwahn, Eva
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Medicinska fakultetenKardiologiska kliniken USAvdelningen för kardiovaskulär medicinAvdelningen för omvårdnad
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International Journal of Cardiology
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