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Short-term side effects and attitudes towards second donation: A comparison of related and unrelated haematopoietic stem cell donors
Uppsala Univ Hosp, Sweden; Uppsala Univ, Sweden.
Uppsala Univ Hosp, Sweden.
Karolinska Univ Hosp, Sweden; Karolinska Univ Hosp, Sweden.
Copenhagen Univ Hosp, Denmark.
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2018 (English)In: Journal of clinical apheresis, ISSN 0733-2459, E-ISSN 1098-1101, Vol. 33, no 3, p. 226-235Article in journal (Refereed) Published
Abstract [en]

The Nordic Register of Haematopoietic Stem Cell Donors (NRHSD) has registered related and unrelated donors from 10 transplant centres in Sweden, Norway, Finland and Denmark since 1998. We present a prospective, observational study of 1,957 donors, focusing mainly on the differences between related and unrelated donors. Related donors are reported to have more comorbidities, but similar side effects compared with unrelated donors. Side effects after BM or PBSC donation are generally of short duration and in this study no deaths, myocardial infarctions, splenic ruptures, or thromboembolic events are reported. Interestingly, related donors express more hesitancy towards donating again when asked 1 month after donation.

Place, publisher, year, edition, pages
WILEY , 2018. Vol. 33, no 3, p. 226-235
Keywords [en]
bone marrow donation; granulocyte colony stimulating factor; healthy donors; peripheral blood stem cell donation
National Category
Anesthesiology and Intensive Care
Identifiers
URN: urn:nbn:se:liu:diva-150502DOI: 10.1002/jca.21576ISI: 000441439100003PubMedID: 28833474OAI: oai:DiVA.org:liu-150502DiVA, id: diva2:1241658
Note

Funding Agencies|Nordic Cancer Union; Swedish Cancer Society; Uppsala-Orebro Regional Research Council

Available from: 2018-08-24 Created: 2018-08-24 Last updated: 2018-08-24

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Sandstedt, Anna
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Department of Social and Welfare StudiesFaculty of Health SciencesDepartment of Haematology
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Citation style
  • apa
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  • modern-language-association-8th-edition
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  • Other style
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Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
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  • asciidoc
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