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Cross-linked superfine electrospun tragacanth-based biomaterial as scaffolds for tissue engineering
Nanotechnology Institute, Amirkabir University of Technology, Tehran, Iran.
Linköping University, Department of Physics, Chemistry and Biology, Sensor and Actuator Systems. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0003-3274-6029
Linköping University, Department of Clinical and Experimental Medicine, Division of Cell Biology. Linköping University, Faculty of Medicine and Health Sciences.
Nanotechnology Institute, Amirkabir University of Technology, Tehran, Iran.
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2016 (English)In: European Cells and Materials, ISSN 1473-2262, E-ISSN 1473-2262, Vol. 31, no Suppl. 1, p. 204-204Article in journal, Meeting abstract (Refereed) Published
Abstract [en]

Natural polymer-based nanofibrous structures promote cell adhesion and proliferation due to their high surface area/volume ratio, high porosity, and similarity to native extracellular matrix in terms of both chemical composition and physical structure. Gum tragacanth (Tg) is a natural polysaccharides obtained from plants. It is a biocompatible, biodegradable and anionic polysaccharides that has been used extensively as an emulsifier in food and pharmaceutical industries. Despite, its good rheological properties and compatibility, the potential biomedical applications of Tg have not been fully investigated. The objective of the present study was to explore the feasibility of combining Tg with gelatin to fabricate a scaffold that serves as a simple collagen-glycosaminoglycans analog for tissue engineering applications, e.g. as a scaffold for human skin epithelial cells.

Place, publisher, year, edition, pages
Davos, Switzerland: AO Research Institute Davos , 2016. Vol. 31, no Suppl. 1, p. 204-204
National Category
Nano Technology
Identifiers
URN: urn:nbn:se:liu:diva-151904OAI: oai:DiVA.org:liu-151904DiVA, id: diva2:1254496
Conference
eCM Meeting Abstracts 2016, Collection 1, Towards Future Regenerative Therapies TERMIS-EU 2016 Conference, June 28 - July 1, Uppsala, Sweden
Available from: 2018-10-09 Created: 2018-10-09 Last updated: 2018-10-19Bibliographically approved

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Cross-linked superfine electrospun tragacanth-based biomaterial as scaffolds for tissue engineering(225 kB)28 downloads
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Mak, Wing CheungCheung, Kwan YeeGriffith, May

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