liu.seSearch for publications in DiVA
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Exploring plasmonic coupling as a stimuli responsive contrast mechanism in multiphoton microscopy
Univ Gothenburg, Sweden.
Univ Gothenburg, Sweden.
Univ Gothenburg, Sweden.
Univ Gothenburg, Sweden; Fluicell AB, Sweden.
Vise andre og tillknytning
2018 (engelsk)Inngår i: PLASMONICS IN BIOLOGY AND MEDICINE XV, SPIE-INT SOC OPTICAL ENGINEERING , 2018, Vol. 10509, artikkel-id 1050907Konferansepaper, Publicerat paper (Fagfellevurdert)
Abstract [en]

A novel approach for optical biosensing can be obtained based multiphoton induced luminescence (MIL) and its dependence on plasmonic coupling. It has been shown that the proximity of spherical AuNPs determines the generation of MIL in far-field multiphoton laser scanning microscopy (MPM). A stimuli responsive contrast mediator with high sensitivity can be created by controlling the aggregated state of AuNP. In this study we explore a system based on spherical AuNPs functionalized with beta-cyclodextrin and multiple beta-D-lactose units (lacto-CD-AuNP). The aim of the beta-D- lactose units is to target cancer cells, based on overexpression of galectin3 (Gal-3) receptors. The results demonstrate that clustering of particles, and thereby MIL signal, was only acquired from tumor cell lines, i.e., SK-MEL-28 and A431, while not from normal keratinocytes (HEKn). Thus further studies should be undertaken to translate the concept to a preclinical setting.

sted, utgiver, år, opplag, sider
SPIE-INT SOC OPTICAL ENGINEERING , 2018. Vol. 10509, artikkel-id 1050907
Serie
Progress in Biomedical Optics and Imaging, ISSN 1605-7422
Emneord [en]
Gold nanoparticles; multiphoton microscopy; biosensing; galactin-3; skin cancer; keratinocytes; multiphoton luminescence
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-153417DOI: 10.1117/12.2288677ISI: 000450861300005ISBN: 978-1-5106-1504-5 (digital)ISBN: 978-1-5106-1503-8 (tryckt)OAI: oai:DiVA.org:liu-153417DiVA, id: diva2:1271469
Konferanse
Conference on Plasmonics in Biology and Medicine XV
Merknad

Funding Agencies|Marie Curie Program [608407]; Swedish Research Council [621-2015-05002]

Tilgjengelig fra: 2018-12-17 Laget: 2018-12-17 Sist oppdatert: 2018-12-17

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekst

Søk i DiVA

Av forfatter/redaktør
Aili, Daniel
Av organisasjonen

Søk utenfor DiVA

GoogleGoogle Scholar

doi
isbn
urn-nbn

Altmetric

doi
isbn
urn-nbn
Totalt: 102 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf