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One-minute through test to distinguish lower respiratory infection by analysis of sputum; exploring the mechanisms
Linköping University, Department of Clinical and Experimental Medicine, Divison of Neurobiology. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Neurosurgery.
Region Östergötland, Center for Diagnostics, Department of Clinical Microbiology.
The Institute for Protein Environmental Afnity Surveys (PEAS Institute), Linköping, Sweden.
Linköping University, Department of Clinical and Experimental Medicine, Divison of Neurobiology. Linköping University, Faculty of Medicine and Health Sciences.
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2018 (English)In: BMC Research Notes, ISSN 1756-0500, E-ISSN 1756-0500, Vol. 11, no 1Article in journal (Refereed) Published
Abstract [en]

Cough and fever are the initial symptoms of lower respiratory infection. Severe cases might be fatal. Therefore, particularly in the non-equipped centers, the lack of diagnostic methods to identify the severe cases has resulted in overconsumption of antibiotics. On the basis of the knowledge about non-specific immune response at the site of injury, we developed a colorimetric dip-test that shows abrupt, sensitive and quite specific color change upon contact with sputum in the cases of lower respiratory infection. We further explored the mechanism of the test.

Place, publisher, year, edition, pages
Springer Nature , 2018. Vol. 11, no 1
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-154615DOI: 10.1186/s13104-018-3771-1OAI: oai:DiVA.org:liu-154615DiVA, id: diva2:1290861
Available from: 2019-02-21 Created: 2019-02-21 Last updated: 2019-05-01

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Publisher's full texthttps://doi.org/10.1186/s13104-018-3771-1

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Ramezani, AmirEng, LarsTurkina, MariaLönn, JohannaTheodorsson, AnnetteNayeri, Fariba
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Divison of NeurobiologyFaculty of Medicine and Health SciencesDepartment of NeurosurgeryDepartment of Clinical MicrobiologyDivision of Neuro and Inflammation Science
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CiteExportLink to record
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