Tactile sensory channels over-ruled by frequency decoding system that utilizes spike pattern regardless of receptor typeVisa övriga samt affilieringar
2019 (Engelska)Ingår i: eLIFE, E-ISSN 2050-084X, Vol. 8, artikel-id e46510Artikel i tidskrift (Refereegranskat) Published
Abstract [en]
The established view is that vibrotactile stimuli evoke two qualitatively distinctive cutaneous sensations, flutter (frequencies amp;lt; 60 Hz) and vibratory hum (frequencies amp;gt; 60 Hz), subserved by two distinct receptor types (Meissners and Pacinian corpuscle, respectively), which may engage different neural processing pathways or channels and fulfil quite different biological roles. In psychological and physiological literature, those two systems have been labelled as Pacinian and non-Pacinian channels. However, we present evidence that low-frequency spike trains in Pacinian afferents can readily induce a vibratory percept with the same low frequency attributes as sinusoidal stimuli of the same frequency, thus demonstrating a universal frequency decoding system. We achieved this using brief low-amplitude pulsatile mechanical stimuli to selectively activate Pacinian afferents. This indicates that spiking pattern, regardless of receptor type, determines vibrotactile frequency perception. This mechanism may underlie the constancy of vibrotactile frequency perception across different skin regions innervated by distinct afferent types.
Ort, förlag, år, upplaga, sidor
Cambridge, United Kingdom: ELIFE SCIENCES PUBLICATIONS LTD , 2019. Vol. 8, artikel-id e46510
Nationell ämneskategori
Biofysik
Identifikatorer
URN: urn:nbn:se:liu:diva-159709DOI: 10.7554/eLife.46510ISI: 000479088400001PubMedID: 31383258OAI: oai:DiVA.org:liu-159709DiVA, id: diva2:1343898
Anmärkning
Funding Agencies|National Health and Medical Research Council [APP1028284, DP170100064]
2019-08-192019-08-192021-12-29Bibliografiskt granskad