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Computational pathology definitions, best practices, and recommendations for regulatory guidance: a white paper from the Digital Pathology Association
PathAI, MA USA.
Univ Pittsburgh, PA USA.
Amgen Inc, CA USA.
Drexel Univ, PA 19104 USA.
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2019 (English)In: Journal of Pathology, ISSN 0022-3417, E-ISSN 1096-9896Article, review/survey (Refereed) Epub ahead of print
Abstract [en]

In this white paper, experts from the Digital Pathology Association (DPA) define terminology and concepts in the emerging field of computational pathology, with a focus on its application to histology images analyzed together with their associated patient data to extract information. This review offers a historical perspective and describes the potential clinical benefits from research and applications in this field, as well as significant obstacles to adoption. Best practices for implementing computational pathology workflows are presented. These include infrastructure considerations, acquisition of training data, quality assessments, as well as regulatory, ethical, and cyber-security concerns. Recommendations are provided for regulators, vendors, and computational pathology practitioners in order to facilitate progress in the field. (c) 2019 The Authors. The Journal of Pathology published by John Wiley amp; Sons Ltd on behalf of Pathological Society of Great Britain and Ireland.

Place, publisher, year, edition, pages
WILEY , 2019.
Keywords [en]
artificial intelligence; computational pathology; convolutional neural networks; digital pathology; deep learning; image analysis; machine learning
National Category
Computer Vision and Robotics (Autonomous Systems)
Identifiers
URN: urn:nbn:se:liu:diva-160596DOI: 10.1002/path.5331ISI: 000484859800001PubMedID: 31355445OAI: oai:DiVA.org:liu-160596DiVA, id: diva2:1355907
Available from: 2019-09-30 Created: 2019-09-30 Last updated: 2019-10-10

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van der Laak, Jeroen
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Division of Radiological SciencesFaculty of Medicine and Health SciencesClinical pathologyCenter for Medical Image Science and Visualization (CMIV)
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Output format
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