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Gold nanomaterials for optical biosensing and bioimaging
Stanford Univ, CA 94305 USA.
Linköping University, Department of Science and Technology, Physics, Electronics and Mathematics. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0002-1829-8138
Linköping University, Department of Science and Technology, Physics, Electronics and Mathematics. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0002-9566-041X
Delhi Technol Univ, India; Delhi Technol Univ, India.
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2021 (English)In: Nanoscale Advances, E-ISSN 2516-0230, Vol. 3, no 10, p. 2679-2698Article, review/survey (Refereed) Published
Abstract [en]

Gold nanoparticles (AuNPs) are highly compelling nanomaterials for biomedical studies due to their unique optical properties. By leveraging the versatile optical properties of different gold nanostructures, the performance of biosensing and biomedical imaging can be dramatically improved in terms of their sensitivity, specificity, speed, contrast, resolution and penetration depth. Here we review recent advances of optical biosensing and bioimaging techniques based on three major optical properties of AuNPs: surface plasmon resonance, surface enhanced Raman scattering and luminescence. We summarize the fabrication methods and optical properties of different types of AuNPs, highlight the emerging applications of these AuNPs for novel optical biosensors and biomedical imaging innovations, and discuss the future trends of AuNP-based optical biosensors and bioimaging as well as the challenges of implementing these techniques in preclinical and clinical investigations.
Place, publisher, year, edition, pages
Royal Society of Chemistry, 2021. Vol. 3, no 10, p. 2679-2698
National Category
Atom and Molecular Physics and Optics
Identifiers
URN: urn:nbn:se:liu:diva-175604DOI: 10.1039/d0na00961jISI: 000639851700001OAI: oai:DiVA.org:liu-175604DiVA, id: diva2:1553822
Note

Funding Agencies|European UnionEuropean Commission [H2020-MSCA-ITN-2018-813680]; CSIR, IndiaCouncil of Scientific & Industrial Research (CSIR) - India; Department of Science and Technology, New Delhi, IndiaDepartment of Science & Technology (India) [DST/INSPIRE/04/2015/000932]; Science & Engineering Research Board (Government of India) [SB/DF/011/2019]; Damon Runyon Cancer Research Foundation (DFS) [06-13]; Susan G. Komen Breast Cancer FoundationSusan G. Komen Breast Cancer Foundation [SAB15-00003]; Mary Kay Foundation [017-14]; Center for Cancer Nanotechnology Excellence and Translation (CCNE-T) [NIH-NCI U54CA151459]; Pew Charitable Trusts; Alexander and Margaret Stewart Trust; Claire Giannini Fund; Donald E. and Delia B. Baxter Foundation; Skippy Frank Foundation

Available from: 2021-05-11 Created: 2021-05-11 Last updated: 2024-01-08

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Razmi, NasrinNur, OmerWillander, Magnus
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