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Changes over time in patient-reported outcomes in patients with heart failure
Linköping University, Department of Health, Medicine and Caring Sciences, Division of Nursing Sciences and Reproductive Health. Linköping University, Faculty of Medicine and Health Sciences.ORCID iD: 0000-0002-4197-4026
Linköping University, Department of Health, Medicine and Caring Sciences, Division of Nursing Sciences and Reproductive Health. Linköping University, Faculty of Medicine and Health Sciences.ORCID iD: 0000-0002-4437-0260
Linköping University, Department of Health, Medicine and Caring Sciences, Division of Nursing Sciences and Reproductive Health. Linköping University, Faculty of Medicine and Health Sciences.ORCID iD: 0000-0002-7493-0353
Rabin Med Ctr, Israel; Tel Aviv Univ, Israel.
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2024 (English)In: ESC Heart Failure, E-ISSN 2055-5822, Vol. 11, no 2, p. 811-818Article in journal (Refereed) Published
Abstract [en]

AimThis paper describes the trajectory during 1 year of four patient-reported outcomes (PROs), namely, sleep, depressive symptoms, health-related quality of life (HrQoL), and well-being, in patients with heart failure (HF), their relationship and the patient characteristics associated with changes in these PROs.Methods and resultsData analyses of PROs from 603 patients (mean age 67 years; 29% female, 60% NYHA II) enrolled in the HF-Wii study. On short term, between baseline and 3 months, 16% of the patients experienced continuing poor sleep, 11% had sustained depressive symptoms, 13% had consistent poor HrQoL, and 13% consistent poor well-being. Across the entire 1-year period only 21% of the patients had good PRO scores at all timepoints (baseline, 3, 6, and 12 months). All others had at least one low score in any of the PROs at some timepoint during the study. Over the 12 months, 17% had consistently poor sleep, 17% had sustained symptoms of depression, 15% consistently rated a poor HrQoL, and 13% poor well-being. Different patient characteristics per PRO were associated with a poor outcomes across the 12 months. Age, education, New York Heart Association, and length of disease were related to two PRO domains and submaximal exercise capacity (6 min test), co-morbidity, and poor physical activity to one.ConclusionIn total, 79% of the patients with HF encountered problems related to sleep, depressive symptoms, HrQoL, and well-being at least once during a 1-year period. This underscores the need for continuous monitoring and follow-up of patients with HF and the need for dynamic adjustments in treatment and care regularly throughout the HF trajectory.

Place, publisher, year, edition, pages
WILEY PERIODICALS, INC , 2024. Vol. 11, no 2, p. 811-818
Keywords [en]
Heart failure; Patient-reported outcomes; Quality of life; Symptoms
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General Practice
Identifiers
URN: urn:nbn:se:liu:diva-200251DOI: 10.1002/ehf2.14648ISI: 001133746900001PubMedID: 38158757OAI: oai:DiVA.org:liu-200251DiVA, id: diva2:1829447
Note

Funding Agencies|Swedish National Science Council [K2013-69X-22302-01-3, 2016-01390]; Swedish National Science Council/Swedish Research Council for Health, Working Life and Welfare, VR-FORTE [2014-4100]; Swedish Heart and Lung Association [E085/12]; Swedish Heart and Lung Foundation [20130340, 20160439]; Vardal Foundation [2014-0018]; Medical Research Council of Southeast Sweden (FORSS) [474681]

Available from: 2024-01-19 Created: 2024-01-19 Last updated: 2024-11-22Bibliographically approved

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Jaarsma, TinyPerkiö Kato, NaokoKlompstra, LeonieStrömberg, Anna

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Jaarsma, TinyPerkiö Kato, NaokoKlompstra, LeonieStrömberg, Anna
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Division of Nursing Sciences and Reproductive HealthFaculty of Medicine and Health SciencesDepartment of Cardiology in Linköping
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