Does consumption of ethanol distort measurements of exhaled nitric oxide?
2005 (English)In: Respiratory Medicine, ISSN 0954-6111, E-ISSN 1532-3064, Vol. 99, no 2, p. 196-199Article in journal (Refereed) Published
Abstract [en]
Background: Measuring FENO is a novel and non-invasive way to monitor airway inflammation (e.g. asthma). This clinical study was designed to investigate whether drinking ethanol might distort FENO measurements. Methods: Twenty healthy subjects drank 0.40 g ethanol/kg body weight in 15 min. Measurement of FENO started ∼ 30 min before drinking and at various times afterwards for 4 h post-dosing. Ethanol concentrations were determined in venous blood by gas chromatography and in end-exhaled breath by infra-red spectrometry. Results: The within subject standard deviation for determination of FENO was 1.3 ppb, corresponding to a CV of 7.7%. The mean change in FENO from pre-drinking levels during the 4 h testing was statistically significant (P
Place, publisher, year, edition, pages
2005. Vol. 99, no 2, p. 196-199
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-31085DOI: 10.1016/j.rmed.2004.06.008Local ID: 16812OAI: oai:DiVA.org:liu-31085DiVA, id: diva2:251908
2009-10-092009-10-092017-12-13