liu.seSearch for publications in DiVA
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Hepatocyte growth factor (HGF) in patients with pneumonia: a comparison between survivors and non-survivors
Department of Infectious Diseases, Count Hospital, Kalmar, Sweden.
Department of Clinical Chemistry, County Hospital, Kalmar.
Department of Clinical Chemistry, County Hospital, Kalmar.
Department of Clinical Physiology, County Hospital, Kalmar, Sweden.
Vise andre og tillknytning
1998 (engelsk)Inngår i: Scandinavian Journal of Infectious Diseases, ISSN 0036-5548, E-ISSN 1651-1980, Vol. 30, nr 4, s. 405-409Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Hepatocyte growth factor (HGF) is a multifunctional growth factor. After lung injury HGF is secreted in the lung and promotes reconstruction of the damaged organ. We measured, retrospectively, the serum HGF concentrations collected on admission in 55 patients with bacterial pneumonia, using an enzyme-linked immunosorbent assay (ELISA). The patients were divided into 3 groups: Group 1 was survivors with normal liver function (n=14), Group 2 was survivors with abnormal liver function (n=31) and Group 3 was non-survivors (n=10). Median concentrations of HGF were elevated in Groups 1 and 2; and no statistically significant difference between these 2 groups was found. Group 3 had a median HGF concentration within the reference range, significantly lower than both Group 1 and Group 2. In addition LDH was significantly higher in non-survivors as compared with survivors. The combination of LDH and HGF concentrations discriminated between survivors and non-survivors (sensitivity 0.90 and specificity 0.96). The results support the hypothesis that increased levels of HGF might be a natural part of the healing process of lung injury, irrespective of liver involvement, and that patients without increased HGF levels, especially those with concomitant liver function impairment, may have a poor prognosis.

sted, utgiver, år, opplag, sider
1998. Vol. 30, nr 4, s. 405-409
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-34233DOI: 10.1080/00365549850160729Lokal ID: 21052OAI: oai:DiVA.org:liu-34233DiVA, id: diva2:255081
Tilgjengelig fra: 2009-10-10 Laget: 2009-10-10 Sist oppdatert: 2017-12-13bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekst

Personposter BETA

Nayeri, Fariba

Søk i DiVA

Av forfatter/redaktør
Nayeri, Fariba
I samme tidsskrift
Scandinavian Journal of Infectious Diseases

Søk utenfor DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric

doi
urn-nbn
Totalt: 85 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf