liu.seSök publikationer i DiVA
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Mechanical efficiency of the trout heart during volume and pressure-loading: Metabolic implications of the stiffness of the ventricular tissue
Department of Zoophysiology, University of Aarhus, DK-8000 Århus C, Denmark.
Department of Zoophysiology, University of Aarhus, DK-8000 Århus C, Denmark.
Linköpings universitet, Institutionen för fysik, kemi och biologi, Zoologi. Linköpings universitet, Tekniska högskolan.
2002 (Engelska)Ingår i: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology, ISSN 0174-1578, E-ISSN 1432-136X, Vol. 172, nr 6, s. 477-484Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

In the mammalian heart the metabolic costs of pressure loading exceed those of volume loading. As evidence suggests that the opposite may be true in fish, we evaluated the metabolic costs of volume and pressure loading in the isolated trout heart and compared the results with the mammalian heart based on the biomechanical properties of cardiac muscle. The highest power output (2.33 ± 0.32 mW g-1, n = 5) appeared at the highest preload pressure tested (0.3 kPa) and at an afterload of 5 kPa. At a higher afterload, power did not increase because stroke volume fell. The highest mechanical efficiency (20.7 ± 2.0%, n = 5) was obtained at a preload of 0.15 kPa and an afterload of 5 kPa. Further increases in preload or afterload did not increase mechanical efficiency, probably because of increases in ventricular wall stress which increased the oxygen consumed disproportionately more than the stroke work. Under pressure unloading (25% decrease in power output), mechanical efficiency was significantly higher in comparison with volume unloading. Given that stiffness of the ventricular tissue is larger in trout than in rat papillary muscles, it is suggested that the increased strain during volume loading is energetically disadvantageous for stiff muscles like those of trout, but it is advantageous when muscle stiffness is lower as it occurs in the rat papillary muscle.

Ort, förlag, år, upplaga, sidor
2002. Vol. 172, nr 6, s. 477-484
Nyckelord [en]
Cardiac energetics, Isolated trout heart, Myocardial stiffness, Pressure loading, Volume loading
Nationell ämneskategori
Teknik och teknologier
Identifikatorer
URN: urn:nbn:se:liu:diva-46807DOI: 10.1007/s00360-002-0270-3OAI: oai:DiVA.org:liu-46807DiVA, id: diva2:267703
Tillgänglig från: 2009-10-11 Skapad: 2009-10-11 Senast uppdaterad: 2017-12-13

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltext

Personposter BETA

Altimiras, Jordi

Sök vidare i DiVA

Av författaren/redaktören
Altimiras, Jordi
Av organisationen
ZoologiTekniska högskolan
I samma tidskrift
Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
Teknik och teknologier

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetricpoäng

doi
urn-nbn
Totalt: 137 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf