liu.seSök publikationer i DiVA
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
A new device for assessing changes in skin viscoelasticity using indentation and optical measurement
University of London Imperial College of Science, Technology and Medicine.
Linköpings universitet, Institutionen för medicinsk teknik, Biomedicinsk instrumentteknik. Linköpings universitet, Tekniska högskolan.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Dermatologi och venerologi. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Medicincentrum, Hudkliniken i Östergötland.
University of Limerick.
2010 (Engelska)Ingår i: SKIN RESEARCH AND TECHNOLOGY, ISSN 0909-752X, Vol. 16, nr 2, s. 210-228Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background/aims Skin is a viscoelastic material, comprised of fluidic and fibrous components. Changes in viscoelasticity can arise due to a number of conditions including dehydration, swelling (associated with injury or disease), impaired heart function, rehydration therapy, ageing, scarring, sun exposure and genetic conditions affecting connective tissue. Quantification of changes in skin viscoelasticity due to these processes is of great clinical interest in the fields of therapy monitoring, wound healing and disease screening. However, devices currently available to measure aspects of the mechanical properties of skin have limitations in ease-of-use, accessibility, and depth of measurement. This paper describes a new technique to follow changes in the viscoelasticity of the skin, using a novel approach to an indentation manoeuvre. The device is portable, low-cost and easy to use while at the same time providing rich information on the mechanical response of the skin. Methods The method proposed optically tracks the skins recovery from an initial strain, made with a novel linear indentor, using diffuse side-lighting and a CCD video camera. Upon indentation, the skins elastin fibres are stretched and fluid is displaced from the compressed region. When the indentor is removed, the rate of recovery of the skin from this imprint is therefore principally dependent on its hydration and elasticity. Using the blue colour plane of the image and polarisation filtering, it is possible to examine the surface topography only, and track the decay of the imprint over time. Results The decrease in size of the imprint over time (decay curve) recorded by the device is shown to agree with the theoretical predictions of an appropriate viscoelastic model of skin mechanical behaviour. The contributors to the response measured using the indentation device are fully characterised and evaluated using separate measurement techniques including high-frequency ultrasound, polarisation spectroscopy and optical coherence tomography. Conclusion The device developed is capable of tracking the viscoelastic response of skin to minimal indentation. The high precision achieved using low-cost materials means that the device could be a viable alternative to current technologies.

Ort, förlag, år, upplaga, sidor
Blackwell Publishing Ltd , 2010. Vol. 16, nr 2, s. 210-228
Nyckelord [en]
skin indentation, viscoelasticity, side illumination, skin recovery
Nationell ämneskategori
Medicin och hälsovetenskap
Identifikatorer
URN: urn:nbn:se:liu:diva-55048DOI: 10.1111/j.1600-0846.2010.00433.xISI: 000276468100012OAI: oai:DiVA.org:liu-55048DiVA, id: diva2:315277
Tillgänglig från: 2010-04-28 Skapad: 2010-04-28 Senast uppdaterad: 2010-04-28

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltext

Personposter BETA

Nilsson, GertAnderson, Chris

Sök vidare i DiVA

Av författaren/redaktören
Nilsson, GertAnderson, Chris
Av organisationen
Biomedicinsk instrumentteknikTekniska högskolanDermatologi och venerologiHälsouniversitetetHudkliniken i Östergötland
Medicin och hälsovetenskap

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetricpoäng

doi
urn-nbn
Totalt: 728 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf