liu.seSearch for publications in DiVA
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Modelling drug-related morbidity in Sweden using an expert panel of physicians
Nordic School of Public Health NHV, Gothenburg, Sweden.
Nordic School of Public Health NHV, Gothenburg, Sweden.
Linköpings universitet, Institutionen för medicin och hälsa, Klinisk farmakologi. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Diagnostikcentrum, Klinisk farmakologi.
Medical Products Agency, Uppsala, Sweden.
Vise andre og tillknytning
2012 (engelsk)Inngår i: European Journal of Clinical Pharmacology, ISSN 0031-6970, E-ISSN 1432-1041, Vol. 68, nr 9, s. 1309-1319Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

PURPOSE: In modelling studies using pharmacists' opinions, drug-related morbidity (DRM) and preventable DRM have been more common than in observational studies, and the resulting costs are extensive. Modelling studies' estimates may vary depending on informants' profession. The purpose of this modelling study was to estimate the proportion of patients with DRM and preventable DRM and the cost of illness (COI) of DRM in Sweden based on physicians' expert opinions. METHOD: A conceptual model of DRM was modified from previous studies. Using a modified Delphi technique, a panel of physicians (n = 19) estimated the probabilities of DRM, preventable DRM, and clinical outcomes of DRM separately for outpatients and inpatients. DRM included new medical problems (adverse drug reactions, drug dependence, and intoxications by overdose) and therapeutic failure (insufficient effects of medicines, and morbidity due to untreated indication). A COI analysis included the direct costs of DRM. RESULTS: Physicians estimated that 51 ± 22% [mean ± standard deviation (SD)] of outpatients experience DRM and 12 ± 8% preventable DRM. Of inpatients, 54 ± 17% was estimated to experience DRM and 16 ± 7% preventable DRM. Of outpatients with DRM, 24 ± 11% was estimated to experience preventable DRM, whereas this proportion for inpatients was 31 ± 15%. The estimated COI was 376 euros per outpatient and 838 euros per inpatient. CONCLUSIONS: Swedish physicians estimated that every other outpatient and inpatient experiences DRM, which is often preventable and costly. As physicians' estimates on the proportion of patients with DRM were higher than in observational studies in restricted subpopulations, DRM may be more common in the general population than observational studies suggest.

sted, utgiver, år, opplag, sider
Springer, 2012. Vol. 68, nr 9, s. 1309-1319
Emneord [en]
Drug-related morbidity, Cost of illness, Preventability, Decision tress, Pharmacoepidemiology
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-76037DOI: 10.1007/s00228-012-1244-3ISI: 000307548400010PubMedID: 22392557OAI: oai:DiVA.org:liu-76037DiVA, id: diva2:512264
Merknad

funding agencies|National Corporation of Swedish Pharmacies (Apoteket AB)||

Tilgjengelig fra: 2012-03-27 Laget: 2012-03-23 Sist oppdatert: 2018-01-12

Open Access i DiVA

fulltext(437 kB)756 nedlastinger
Filinformasjon
Fil FULLTEXT01.pdfFilstørrelse 437 kBChecksum SHA-512
413145fae740784a1d479b5cdc65255969f0e5f4161fe2cb3d9af176b75109adda67b8a8362013eb96c5b9de8065f02856a9aa7b7947e32633ac38c4b36772a0
Type fulltextMimetype application/pdf

Andre lenker

Forlagets fulltekstPubMed

Personposter BETA

Hägg, Staffan

Søk i DiVA

Av forfatter/redaktør
Hägg, Staffan
Av organisasjonen
I samme tidsskrift
European Journal of Clinical Pharmacology

Søk utenfor DiVA

GoogleGoogle Scholar
Totalt: 756 nedlastinger
Antall nedlastinger er summen av alle nedlastinger av alle fulltekster. Det kan for eksempel være tidligere versjoner som er ikke lenger tilgjengelige

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 200 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf