liu.seSök publikationer i DiVA
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Stem cells and enhanced healing of chronic tympanic membrane perforation
Karolinska Institute/Karolinska University Hospital, Stockholm, Sweden.
Karolinska Institute/Karolinska University Hospital, Stockholm, Sweden.
University of Antwerp, Groenenburgerlaan, Belgium .
Karolinska Institute/Karolinska University Hospital, Stockholm, Sweden.
Visa övriga samt affilieringar
2008 (Engelska)Ingår i: Acta Oto-Laryngologica, ISSN 0001-6489, E-ISSN 1651-2251, Vol. 128, nr 4, s. 352-359Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

CONCLUSIONS:

Important information about the basic reparative process of tympanic membrane (TM) healing is shown, which can be incorporated for further clinical understanding. This provides a basis for the exploration of stem cell treatment for TM perforations and holds promise for future improvements.

OBJECTIVES:

This study aimed to analyse the healing of TM perforation by using stem cells and the stiffness of the membrane was tested in an acute and long-term study.

MATERIALS AND METHODS:

Sprague-Dawley rats were used in a model of TM perforation. The perforation was performed with a laser system. Stem cells were applied and the healing time and morphological analysis were performed with light and transmission electron microscope. Stiffness was examined by moiré interferometry.

RESULTS:

The stiffness of the perforated and healed TM was restored after just 2 weeks. In the chronic perforation model, mesenchymal stem cells enhanced the healing.

Ort, förlag, år, upplaga, sidor
Informa Healthcare, 2008. Vol. 128, nr 4, s. 352-359
Nyckelord [en]
tympanic membrane; laser myringotomy; healing; moire interferometry; stem cell
Nationell ämneskategori
Medicin och hälsovetenskap
Identifikatorer
URN: urn:nbn:se:liu:diva-101022DOI: 10.1080/00016480701762508ISI: 000254394600003PubMedID: 18368564OAI: oai:DiVA.org:liu-101022DiVA, id: diva2:665052
Tillgänglig från: 2013-11-18 Skapad: 2013-11-18 Senast uppdaterad: 2017-12-06

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Olivius, Petri

Sök vidare i DiVA

Av författaren/redaktören
Olivius, Petri
I samma tidskrift
Acta Oto-Laryngologica
Medicin och hälsovetenskap

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 39 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf