liu.seSök publikationer i DiVA
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Cognitive impairment and its consequences in everyday life
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för kliniska vetenskaper. Linköpings universitet, Hälsouniversitetet. Region Östergötland, Närsjukvården i centrala Östergötland, Geriatriska kliniken.ORCID-id: 0000-0003-4166-7269
2015 (Engelska)Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
Abstract [en]

The overall aim was to improve knowledge of the consequences of cognitive dysfunction in everyday life and of instruments to make these assessments. The thesis contains four studies each of different design using different populations.

In study I, the relationship between cognitive function, ability to perform activities of daily living and perceived health-related quality of life were investigated in a population of 85-year-old individuals in the community of Linköping (n = 373). The study was part of the Elderly in Linköping Screening Assessment 85 (ELSA 85). Even mild cognitive dysfunction correlated with impaired ability to perform activities of daily living and lower health-related quality of life.

In study II, the diagnostic accuracy and clinical utility of Cognistat, a cognitive screening instrument, were evaluated for identifying individuals with cognitive impairment in a primary care population. Cognistat has relatively good diagnostic accuracy with a sensitivity of 0.85, a specificity of 0.79 and a Clinical Utility Index (CUI) of 0.72. The corresponding values were 0.59, 0.91 and 0.53 for the Mini Mental State Examination (MMSE), and 0.26, 0.88 and 0.20 for the Clock Drawing Test (CDT).

In study III, the aim was to develop an instrument measuring self-perceived or caregiver reported ability to perform everyday life activities in persons with suspected cognitive impairment or dementia and to perform psychometric testing of this instrument, named the Cognitive Impairment in Daily Life (CID). The CID was found to have good content validity.

In study IV, experiences of cognitive impairment, its consequences in everyday life and the need for support in persons with mild cognitive impairment (MCI) or mild dementia and their relatives were explored. Interviews were performed with five people with MCI, eight people with mild dementia and their relatives (n = 13). The main finding was that persons with MCI and dementia experienced cognitive changes that could be burdensome and result in changed activity patterns.

In conclusion, the findings support earlier research and show that cognitive dysfunction even at mild stages has an impact on everyday life and reduces perceived quality of life. To improve interventions for persons with cognitive impairment, it is important to assess not only cognitive function but also its consequences in everyday life activities.

Ort, förlag, år, upplaga, sidor
Linköping: Linköping University Electronic Press, 2015. , s. 54
Serie
Linköping University Medical Dissertations, ISSN 0345-0082 ; 1452
Nyckelord [en]
Activities of daily living, assessment, dementia, mild cognitive impairment, occupational therapy, quality of life
Nationell ämneskategori
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi Geriatrik
Identifikatorer
URN: urn:nbn:se:liu:diva-115349DOI: 10.3384/diss.diva-115349ISBN: 978-91-7519-109-6 (tryckt)OAI: oai:DiVA.org:liu-115349DiVA, id: diva2:794905
Disputation
2015-04-10, Berzeliussalen, Campus US, Linköping, 09:00 (Svenska)
Opponent
Handledare
Tillgänglig från: 2015-03-13 Skapad: 2015-03-13 Senast uppdaterad: 2019-11-15Bibliografiskt granskad
Delarbeten
1. Cognition, daily living, and health-related quality of life in 85-year-olds in Sweden
Öppna denna publikation i ny flik eller fönster >>Cognition, daily living, and health-related quality of life in 85-year-olds in Sweden
2012 (Engelska)Ingår i: Aging, Neuropsychology and Cognition, ISSN 1382-5585, E-ISSN 1744-4128, Vol. 19, nr 3, s. 421-432Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

This study investigates how cognition influences activities of daily living and health-related quality of life in 85-year-olds in Sweden (n = 373). Data collection included a postal questionnaire comprising demographics and health-related quality of life measured by the EQ-5D. The ability to perform personal activities of daily living (PADL) was assessed during a home visit that included administering the Mini Mental State Examination (MMSE). Cognitive impairment was shown in 108 individuals (29%). The majority were independent with respect to PADL. A larger number of participants with cognitive impairment reported that they needed assistance in instrumental activities of daily living (IADL) compared to the group without cognitive impairment. Impaired cognition was significantly related to problems with IADL. Significant but low correlations were found between cognition and health-related quality of life – higher ratings on perceived quality of life correlated with higher results on the MMSE.

Ort, förlag, år, upplaga, sidor
Taylor & Francis, 2012
Nyckelord
Elderly; Cognitive impairment; Population study; Daily living; Quality
Nationell ämneskategori
Medicin och hälsovetenskap
Identifikatorer
urn:nbn:se:liu:diva-77575 (URN)10.1080/13825585.2011.629290 (DOI)000306171800005 ()
Tillgänglig från: 2012-05-23 Skapad: 2012-05-23 Senast uppdaterad: 2017-12-07
2. Clinical Utility of Cognistat in Multiprofessional Team Evalutations of Patients with Cognitive Impairment in Swedish Primary Care
Öppna denna publikation i ny flik eller fönster >>Clinical Utility of Cognistat in Multiprofessional Team Evalutations of Patients with Cognitive Impairment in Swedish Primary Care
2014 (Engelska)Ingår i: International Journal of Family Medicine, ISSN 2090-2042, E-ISSN 2090-2050, Vol. 2014, s. 649253-Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background. Diagnostic evaluations of dementia are often performed in primary health care (PHC). Cognitive evaluation requires validated instruments.

Objective. To investigate the diagnostic accuracy and clinical utility of Cognistat in a primary care population.

Methods. Participants were recruited from 4 PHC centres; 52 had cognitive symptoms and 29 were presumed cognitively healthy. Participants were tested using the Mini-Mental State Examination (MMSE), the Clock Drawing Test (CDT), and Cognistat. Clinical diagnoses, based on independent neuropsychological examination and a medical consensus discussion in secondary care, were used as criteria for diagnostic accuracy analyses.

Results. The sensitivity, specificity, positive predictive value, and negative predictive value were 0.85, 0.79, 0.85, and 0.79, respectively, for Cognistat; 0.59, 0.91, 0.90, and 0.61 for MMSE; 0.26, 0.88, 0.75, and 0.46 for CDT; 0.70, 0.79, 0.82, and 0.65 for MMSE and CDT combined. The area under the receiver operating characteristic curve was 0.82 for Cognistat, 0.75 for MMSE, 0.57 for CDT, and 0.74 for MMSE and CDT combined.

Conclusions. The diagnostic accuracy and clinical utility of Cognistat was better than the other tests alone or combined. Cognistat is well adapted for cognitive evaluations in PHC and can help the general practitioner to decide which patients should be referred to secondary care.

 

Ort, förlag, år, upplaga, sidor
Hindawi Publishing Corporation, 2014
Nationell ämneskategori
Klinisk medicin
Identifikatorer
urn:nbn:se:liu:diva-107048 (URN)10.1155/2014/649253 (DOI)
Tillgänglig från: 2014-06-04 Skapad: 2014-06-04 Senast uppdaterad: 2019-09-20Bibliografiskt granskad
3. Development of an instrument for measuring activities of daily living in persons with suspected cognitive impairment
Öppna denna publikation i ny flik eller fönster >>Development of an instrument for measuring activities of daily living in persons with suspected cognitive impairment
2016 (Engelska)Ingår i: Scandinavian Journal of Occupational Therapy, ISSN 1103-8128, E-ISSN 1651-2014, Vol. 23, nr 3, s. 230-239Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: According to the Swedish National Board of Health and Welfare, structured assessment of function and activity has high priority when investigating for dementia.

Aim/objectives: The aim was to develop and psychometrically test an instrument to measure self-reported and/or informant-reported ability to perform activities of daily living in persons with suspected cognitive impairment.

Material and methods: The Cognitive Impairment in Daily Life (CID) instrument has been developed in several phases. Content validity was achieved through five expert panels using a Content Validity Index (CVI). The content was tested further in a pilot study of 51 patients and 49 relatives from primary care or a specialist memory clinic.

Results: Content validity was good with a CVI index of 0.83. All patients considered that relevant activities were included. Most relatives considered that the activities included in the instrument were adequate and captured the patients’ difficulties in daily life. Some adjustments to the items and scale were suggested and these were done after each phase. In general, relatives indicated more difficulties than patients.

Conclusion: The CID instrument seems promising in terms of content validity. Further testing of reliability and construct validity is ongoing.

Nyckelord
Cognition, dementia investigation, instrument development
Nationell ämneskategori
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Identifikatorer
urn:nbn:se:liu:diva-115306 (URN)10.3109/11038128.2016.1139621 (DOI)000374634100006 ()
Tillgänglig från: 2015-03-13 Skapad: 2015-03-13 Senast uppdaterad: 2017-12-04Bibliografiskt granskad
4. Cognitive impairment and its consequences in everyday life: experiences of people with mild cognitive impairment or mild dementia and their relatives
Öppna denna publikation i ny flik eller fönster >>Cognitive impairment and its consequences in everyday life: experiences of people with mild cognitive impairment or mild dementia and their relatives
2015 (Engelska)Ingår i: International psychogeriatrics, ISSN 1041-6102, E-ISSN 1741-203X, Vol. 27, nr 6, s. 949-958Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Background: The aim of this study was to explore experiences of cognitive impairment, its consequences in everyday life and need for support in people with mild cognitive impairment (MCI) or mild dementia and their relatives.

Methods: A qualitative approach with an explorative design with interviews was chosen. The participants included five people with MCI and eight people with mild dementia and their relatives. All participants were recruited at a geriatric memory clinic in Sweden. The Grounded Theory method was used.

Results: The following categories emerged: noticing cognitive changes; changed activity patterns; coping strategies; uncertainty about own ability and environmental reactions; support in everyday life; support from the healthcare system; consequences in everyday life for relatives; and support for relatives. The main findings were that people with MCI and dementia experienced cognitive changes that could be burdensome and changed activity patterns. Most of them, however, considered themselves capable of coping on their own. The relatives noticed cognitive changes and activity disruptions to a greater extent and tried to be supportive in everyday life. Degree of awareness varied and lack of awareness could lead to many problems in everyday life.

Conclusions: Perceived cognitive impairment and its consequences in everyday life were individual and differed among people with MCI or dementia and their relatives. Thus, healthcare professionals must listen to both people with cognitive impairment and their relatives for optimal individual care planning. Support such as education groups and day care could be more tailored towards the early stages of dementia.

Ort, förlag, år, upplaga, sidor
Cambridge University Press, 2015
Nyckelord
Alzheimer’s disease; activities of daily living; qualitative research
Nationell ämneskategori
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Identifikatorer
urn:nbn:se:liu:diva-115307 (URN)10.1017/S1041610215000058 (DOI)000354093800009 ()25644289 (PubMedID)
Tillgänglig från: 2015-03-13 Skapad: 2015-03-13 Senast uppdaterad: 2017-12-04Bibliografiskt granskad

Open Access i DiVA

fulltext(804 kB)14362 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 804 kBChecksumma SHA-512
84a881778d116c4b2f247d536aaff8eb8ada380a69df4cca8cde5dacd16e46afd430382a4891e0d933e12b960a62c836f8ef851cf614087bae32e20f1d82fa4e
Typ fulltextMimetyp application/pdf
omslag(2931 kB)61 nedladdningar
Filinformation
Filnamn COVER01.pdfFilstorlek 2931 kBChecksumma SHA-512
d28ead39aa4381865e219e20a8ca6f7e8d54a7fb2ca151dae31093edbbba01cebcd3a55aa580dd65935f6c54ff3573b48dd0282fa23becae33aeeb7ee8c6c725
Typ coverMimetyp application/pdf
Beställ online >>

Övriga länkar

Förlagets fulltext

Personposter BETA

Johansson, Maria

Sök vidare i DiVA

Av författaren/redaktören
Johansson, Maria
Av organisationen
Avdelningen för kliniska vetenskaperHälsouniversitetetGeriatriska kliniken
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologiGeriatrik

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 14362 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
isbn
urn-nbn

Altmetricpoäng

doi
isbn
urn-nbn
Totalt: 7169 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf