liu.seSök publikationer i DiVA
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Supported lipid bilayer formation and lipid-membrane-mediated biorecognition reactions studied with a new nanoplasmonic sensor template
DiVision of Solid State Physics, Lund UniVersity, SE-22100 Lund, Sweden.ORCID-id: 0000-0002-3002-3639
DiVision of Solid State Physics, Lund UniVersity, SE-22100 Lund, Sweden.
DiVision of Solid State Physics, Lund UniVersity, SE-22100 Lund, Sweden.
DiVision of Solid State Physics, Lund UniVersity, SE-22100 Lund, Sweden.
2007 (Engelska)Ingår i: Nano letters (Print), ISSN 1530-6984, E-ISSN 1530-6992, Vol. 7, nr 11, s. 3462-3468Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

This paper presents the use of the localized surface plasmon resonance (LSPR) sensor concept to probe the formation of macroscopic and laterally mobile supported lipid bilayers (SLBs) on SiO(x)-encapsulated nanohole-containing Au and Ag films. A comparison between Au- and Ag-based sensor templates demonstrates a higher sensitivity for Au-based templates with respect to both bulk and interfacial refractive index (RI) changes in aqueous solution. The lateral mobility of SLBs formed on the SiO(x)-rencapsulated nanohole templates was analyzed using fluorescence recovery after photobleaching (FRAP), demonstrating essentially complete (greater than96%) recovery, but a reduction in diffusivity of about 35% compared with SLBs formed on flat SiO(x) substrates. Furthermore, upon SLB formation, the temporal variation in extinction peak position of the LSPR active templates display a characteristic shape, illustrating what, to the best of our knowledge, is the first example where the nanoplasmonic concept is shown capable of probing biomacromolecular structural changes without the introduction of labels. With a signal-to-noise ratio better than 5 X 10(2) upon protein binding to the cell-membrane mimics, the sensor concept is also proven competitive with state-of-the-art label-free sensors.

Ort, förlag, år, upplaga, sidor
American Chemical Society , 2007. Vol. 7, nr 11, s. 3462-3468
Nationell ämneskategori
Biofysik
Identifikatorer
URN: urn:nbn:se:liu:diva-118834DOI: 10.1021/nl072006tISI: 000251059800038PubMedID: 17902726OAI: oai:DiVA.org:liu-118834DiVA, id: diva2:817128
Tillgänglig från: 2015-06-04 Skapad: 2015-06-04 Senast uppdaterad: 2017-12-04

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMed

Person

Jonsson, Magnus P.

Sök vidare i DiVA

Av författaren/redaktören
Jonsson, Magnus P.
I samma tidskrift
Nano letters (Print)
Biofysik

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 363 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • oxford
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf