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Two dimensional vibrations of the guinea pig apex organ of Corti measured in vivo using phase sensitive Fourier domain optical coherence tomography
Oregon Health and Science University, OR 97239 USA.
Oregon Health and Science University, OR 97239 USA.
Oregon Health and Science University, OR 97239 USA.
Linköpings universitet, Institutionen för klinisk och experimentell medicin, Avdelningen för cellbiologi. Linköpings universitet, Medicinska fakulteten.
Vise andre og tillknytning
2015 (engelsk)Inngår i: PHOTONIC THERAPEUTICS AND DIAGNOSTICS XI, Society of Photo-optical Instrumentation Engineers (SPIE) , 2015, Vol. 9303, nr 93031L, s. 93031L-Konferansepaper, Publicerat paper (Fagfellevurdert)
Abstract [en]

In this study, we measure the in vivo apical-turn vibrations of the guinea pig organ of Corti in both axial and radial directions using phase-sensitive Fourier domain optical coherence tomography. The apical turn in guinea pig cochlea has best frequencies around 100 - 500 Hz which are relevant for human speech. Prior measurements of vibrations in the guinea pig apex involved opening the otic capsule, which has been questioned on the basis of the resulting changes to cochlear hydrodynamics. Here this limitation is overcome by measuring the vibrations through bone without opening the otic capsule. Furthermore, we have significantly reduced the surgery needed to access the guinea pig apex in the axial direction by introducing a miniature mirror inside the bulla. The method and preliminary data are discussed in this article.

sted, utgiver, år, opplag, sider
Society of Photo-optical Instrumentation Engineers (SPIE) , 2015. Vol. 9303, nr 93031L, s. 93031L-
Serie
Proceedings of SPIE, ISSN 0277-786X ; 9303
Emneord [en]
Optical coherence tomography; optical interferometry; phase-sensitive Fourier domain OCT; cochlear vibration; biomedical optical imaging; speech
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-119274DOI: 10.1117/12.2079673ISI: 000354366400026ISBN: 978-1-62841-393-9 (tryckt)OAI: oai:DiVA.org:liu-119274DiVA, id: diva2:820535
Konferanse
Conference on Photonic Therapeutics and Diagnostics XI
Tilgjengelig fra: 2015-06-12 Laget: 2015-06-12 Sist oppdatert: 2015-06-12

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Totalt: 196 treff
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