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Serum levels of scc, cea, ca-125 and tpa in the management of cervical-carcinoma.
Department of Obstetrics and Gynecology, Karolinska Hospital, Stockholm, Sweden.
Department of Obstetrics and Gynecology, Karolinska Hospital, Stockholm, Sweden.
Department of Obstetrics and Gynecology, Karolinska Hospital, Stockholm, Sweden.
Unit for applied biochemistry, clinical research center, Huddinge hospital, Stockholm, Sweden.
1995 (English)In: Oncology Reports, ISSN 1021-335X, E-ISSN 1791-2431, Vol. 2, no 4Article in journal (Refereed) Published
Abstract [en]

Serum levels of squamous cell carcinoma antigen (SCC), carcinoembryonic antigen (CEA), CA 125 and tissue polypeptide antigen (TPA) were serially determined in 116 patients with cervical carcinoma. Serum levels of SCC or TPA levels were elevated in the 12 patients with residual tumour after primary therapy. In patients who were clinically in complete remission, SCC and TPA levels were elevated in 7/69 and 5/70 patients, respectively. Three of the 7 with positive SCC and 4 of the 5 patients with positive TPA levels had a recurrence during follow-up. Elevated levels of SCC or CA 125 or TPA preceded the clinical detection of recurrence in 13 of 18 patients (median time was 7 months for SCC and 6 months for CA 125 and TPA).

Place, publisher, year, edition, pages
1995. Vol. 2, no 4
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:liu:diva-133687PubMedID: 21597788OAI: oai:DiVA.org:liu-133687DiVA: diva2:1062618
Available from: 2017-01-07 Created: 2017-01-07 Last updated: 2017-01-22

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