liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Optical guidance for stereotactic brain tumor biopsy procedures-preliminary clinical evaluation
Linköping University, Department of Biomedical Engineering, Biomedical Instrumentation. Linköping University, Faculty of Medicine and Health Sciences. (MINT)ORCID iD: 0000-0002-0555-8877
Linköping University, Department of Biomedical Engineering. Linköping University, Faculty of Science & Engineering. (MINT)
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuro and Inflammation Science. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Anaesthetics, Operations and Specialty Surgery Center, Department of Neurosurgery. (MINT)
Linköping University, Department of Clinical and Experimental Medicine, Division of Neuro and Inflammation Science. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Diagnostics, Department of Clinical Pathology and Clinical Genetics.
Show others and affiliations
2017 (English)Conference paper, (Refereed)
Abstract [en]

During stereotactic biopsy on suspected tumors in the brain, tissue samples are harvested to determine the malignancy. To provide guidance for finding the diagnostic tumor sites and to avoid vessel rupture, an application specific probe was developed. The setup incorporated spectroscopy for detection of 5-aminolevulinic acid induced protoporphyrin (PpIX) fluorescence and blood flow using laser Doppler flowmetry. The PpIX fluorescence was significantly different in the tumor compared to the gliotic marginal zone (p < 0.05). In conclusion, the systems made real-time tumor detection and vessel tracking possible. Moreover, the autofluorescence and blood perfusion could be studied in the tumor.

Place, publisher, year, edition, pages
SPIE - International Society for Optical Engineering, 2017.
Series
Clinical and Translational Neurophotonics
National Category
Other Medical Engineering
Identifiers
URN: urn:nbn:se:liu:diva-134373OAI: oai:DiVA.org:liu-134373DiVA: diva2:1072536
Conference
Photonics West 28 January - 2 February 2017
Funder
Linköpings universitetSwedish Childhood Cancer FoundationWenner-Gren FoundationsMedical Research Council of Southeast Sweden (FORSS)
Available from: 2017-02-08 Created: 2017-02-08 Last updated: 2017-02-20Bibliographically approved

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Haj-Hosseini, NedaRichter, JohanMilos, PeterHallbeck, MartinWårdell, Karin
By organisation
Biomedical InstrumentationFaculty of Medicine and Health SciencesDepartment of Biomedical EngineeringFaculty of Science & EngineeringDivision of Neuro and Inflammation ScienceDepartment of NeurosurgeryDepartment of Clinical Pathology and Clinical Genetics
Other Medical Engineering

Search outside of DiVA

GoogleGoogle Scholar

Total: 310 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf