liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Olfactory Sensitivity for the Mammalian Blood Odor Component Trans-4,5-epoxy-(E)-2-decenal in CD-1 Mice.
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, Faculty of Science & Engineering.
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0001-5583-2697
2017 (English)In: Perception, ISSN 0301-0066, E-ISSN 1468-4233, Vol. 46, no 3-4, 333-342 p.Article in journal (Refereed) Published
Abstract [en]

Using a conditioning paradigm and an automated olfactometer, we investigated the olfactory sensitivity of CD-1 mice for the mammalian blood odor component trans-4,5-epoxy-(E)-2-decenal. We found that two of the animals significantly discriminated concentrations down to 3.0 ppt (parts per trillion) from the solvent, and three animals even successfully detected dilutions as low as 0.3 ppt. Intraspecific comparisons between the olfactory detection thresholds obtained here with those obtained in earlier studies with other odorants show that mice are extraordinarily sensitive to this blood odor component. Interspecific comparisons of olfactory detection thresholds show that human subjects are even more sensitive to trans-4,5-epoxy-(E)-2-decenal than the mice tested here. Both intra- and inter-specific comparisons suggest that neither neuroanatomical properties such as the size of the olfactory epithelium, the total number of olfactory receptor neurons, or the size of olfactory brain structures, nor genetic properties such as the number of functional olfactory receptor genes or the proportion of functional relative to the total number of olfactory receptor genes allow us to reliably predict a species' olfactory sensitivity. In contrast, the results support the notion that the behavioral relevance of an odorant rather than neuroanatomical or genetic properties may determine a species' olfactory sensitivity.

Place, publisher, year, edition, pages
Sage Publications, 2017. Vol. 46, no 3-4, 333-342 p.
Keyword [en]
5-epoxy-(E)-2-decenal, CD-1 mice, blood odor component, olfactory detection thresholds, trans-4
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:liu:diva-136029DOI: 10.1177/0301006616653136ISI: 000397168400008PubMedID: 27251166OAI: oai:DiVA.org:liu-136029DiVA: diva2:1084679
Available from: 2017-03-27 Created: 2017-03-27 Last updated: 2017-04-20

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Sarrafchi, AmirLaska, Matthias
By organisation
BiologyFaculty of Science & Engineering
In the same journal
Perception
Biological Sciences

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 10 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf