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Tools for Coping with Diagnostic Uncertainty
Linköping University, Department of Clinical and Experimental Medicine, Division of Microbiology and Molecular Medicine. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center for Diagnostics, Department of Clinical Chemistry.
2017 (English)In: Clinics in Laboratory Medicine, ISSN 0272-2712, E-ISSN 1557-9832, Vol. 37, no 1, 15-+ p.Article in journal (Refereed) Published
Abstract [en]

Laboratory medicine decreases diagnostic uncertainty, but is influenced by factors causing uncertainties. Error and uncertainty methods are commonly seen as incompatible in laboratory medicine. New versions of the Guide to the Expression of Uncertainty in Measurement and International Vocabulary of Metrology will incorporate both uncertainty and error methods, which will assist collaboration between metrology and laboratories. Law of propagation of uncertainty and bayesian statistics are theoretically preferable to frequentist statistical methods in diagnostic medicine. However, frequentist statistics are better known and more widely practiced. Error and uncertainty methods should both be recognized as legitimate for calculating diagnostic uncertainty.

Place, publisher, year, edition, pages
W B SAUNDERS CO-ELSEVIER INC , 2017. Vol. 37, no 1, 15-+ p.
Keyword [en]
Law of propagation of uncertainty (LPU); Uncertainty methods; Error methods; Diagnostic uncertainty; Bayesian statistics; Frequentist statistics
National Category
Cancer and Oncology
Identifiers
URN: urn:nbn:se:liu:diva-136299DOI: 10.1016/j.cll.2016.09.002ISI: 000394829600003PubMedID: 28153362OAI: oai:DiVA.org:liu-136299DiVA: diva2:1087983
Available from: 2017-04-10 Created: 2017-04-10 Last updated: 2017-04-10

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Theodorsson, Elvar
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