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Collagen-Based Photoactive Agent for Tissue Bonding
Linköping University, Department of Clinical and Experimental Medicine, Division of Cell Biology. Linköping University, Faculty of Medicine and Health Sciences. University of Ottawa, Canada.
University of Ottawa, Canada.
University of Ottawa, Canada.
University of Ottawa, Canada.
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2017 (English)In: ACS Applied Materials and Interfaces, ISSN 1944-8244, E-ISSN 1944-8252, Vol. 9, no 11, 9265-9270 p.Article in journal (Refereed) Published
Abstract [en]

Using a combination of methacrylated, collagen and the photosensitizer rose Bengal, a new light-activated biomimetic material for tissue sutureless bonding was developed. This formulation was cross-linked using green light. In vivo tests in mice demonstrate the suitability of the material for sutureless wound closure.

Place, publisher, year, edition, pages
AMER CHEMICAL SOC , 2017. Vol. 9, no 11, 9265-9270 p.
Keyword [en]
tissue photobonding; rose Bengal; collagen; wound healing; cross-linking
National Category
Polymer Chemistry
Identifiers
URN: urn:nbn:se:liu:diva-136583DOI: 10.1021/acsami.7b01984ISI: 000397478100010PubMedID: 28282110OAI: oai:DiVA.org:liu-136583DiVA: diva2:1089997
Note

Funding Agencies|Natural Sciences and Engineering Research Council (NSERC) [RGPIN- 2015-0632, 342107]; AFA Forsakring, Sweden; UOHI start-up grant [1255]; Burroughs Wellcome Fund

Available from: 2017-04-21 Created: 2017-04-21 Last updated: 2017-04-21

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