liu.seSearch for publications in DiVA
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Modeling Suspension Cultures of Microbial and Mammalian Cells with an Adaptable Six-Compartment Model
University of Appl Science Bremen, Germany.
Linköping University, Department of Physics, Chemistry and Biology. Linköping University, Faculty of Science & Engineering. University of Appl Science Bremen, Germany.
Hamburg University of Technology, Germany.
Linköping University, Department of Physics, Chemistry and Biology, Biotechnology. Linköping University, Faculty of Science & Engineering.
Show others and affiliations
2017 (English)In: Chemical Engineering & Technology, ISSN 0930-7516, E-ISSN 1521-4125, Vol. 40, no 5, 956-966 p.Article in journal (Refereed) Published
Abstract [en]

Process models can be used for model-based control strategies, but model development is a time-consuming and laborious task. To reduce the modeling effort, a new structured compartment model was developed, which may easily be adapted to different cultivation processes. The proposed six-compartment model was used to describe the time courses of cultivations of bacteria, yeast, fungi, and mammalian cell lines, namely, Escherichia coli,Lactobacillus delbrueckii, Saccharomyces cerevisiae, Cyathus striatus, and a hybridoma mammalian cell line. The model can describe the time courses of important state variables and can be adapted to the cultivation processes by parameterization. This reduces the modeling effort for a new process significantly.

Place, publisher, year, edition, pages
WILEY-V C H VERLAG GMBH , 2017. Vol. 40, no 5, 956-966 p.
Keyword [en]
Compartment models; Fungi; Mammalian cells; Microorganisms; Suspension cultivation
National Category
Control Engineering
Identifiers
URN: urn:nbn:se:liu:diva-137594DOI: 10.1002/ceat.201600639ISI: 000399971100018OAI: oai:DiVA.org:liu-137594DiVA: diva2:1097376
Note

Funding Agencies|Bundesministerium fur Bildung und Forschung [FKZ: 031A124 A-C]; City University of Applied Sciences Bremen

Available from: 2017-05-22 Created: 2017-05-22 Last updated: 2017-05-22

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Gerlach, IngaMandenius, Carl-Fredrik
By organisation
Department of Physics, Chemistry and BiologyFaculty of Science & EngineeringBiotechnology
In the same journal
Chemical Engineering & Technology
Control Engineering

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 102 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf